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Discovery of a 5 H -Benzo[4,5]cyclohepta[1,2- b ]pyridin-5-one (MK-2461) Inhibitor of c-Met Kinase for the Treatment of Cancer

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Bibliographic Details
Published in:Journal of medicinal chemistry 2011-06, Vol.54 (12), p.4092-4108
Main Authors: Katz, Jason D., Jewell, James P., Guerin, David J., Lim, Jongwon, Dinsmore, Christopher J., Deshmukh, Sujal V., Pan, Bo-Sheng, Marshall, C. Gary, Lu, Wei, Altman, Michael D., Dahlberg, William K., Davis, Lenora, Falcone, Danielle, Gabarda, Ana E., Hang, Gaozhen, Hatch, Harold, Holmes, Rachael, Kunii, Kaiko, Lumb, Kevin J., Lutterbach, Bart, Mathvink, Robert, Nazef, Naim, Patel, Sangita B., Qu, Xianlu, Reilly, John F., Rickert, Keith W., Rosenstein, Craig, Soisson, Stephen M., Spencer, Kerrie B., Szewczak, Alexander A., Walker, Deborah, Wang, Wenxian, Young, Jonathan, Zeng, Qinwen
Format: Article
Language:English
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ISSN:0022-2623
1520-4804
DOI:10.1021/jm200112k