Cavity-Type DNA Origami-Based Plasmonic Nanostructures for Raman Enhancement

DNA origami has been established as addressable templates for site-specific anchoring of gold nanoparticles (AuNPs). Given that AuNPs are assembled by charged DNA oligonucleotides, it is important to reduce the charge repulsion between AuNPs–DNA and the template to realize high yields. Herein, we de...

Full description

Saved in:
Bibliographic Details
Published in:ACS applied materials & interfaces 2017-07, Vol.9 (26), p.21942-21948
Main Authors: Zhao, Mengzhen, Wang, Xu, Ren, Shaokang, Xing, Yikang, Wang, Jun, Teng, Nan, Zhao, Dongxia, Liu, Wei, Zhu, Dan, Su, Shao, Shi, Jiye, Song, Shiping, Wang, Lihua, Chao, Jie, Wang, Lianhui
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:DNA origami has been established as addressable templates for site-specific anchoring of gold nanoparticles (AuNPs). Given that AuNPs are assembled by charged DNA oligonucleotides, it is important to reduce the charge repulsion between AuNPs–DNA and the template to realize high yields. Herein, we developed a cavity-type DNA origami as templates to organize 30 nm AuNPs, which formed dimer and tetramer plasmonic nanostructures. Transmission electron microscopy images showed that high yields of dimer and tetramer plasmonic nanostructures were obtained by using the cavity-type DNA origami as the template. More importantly, we observed significant Raman signal enhancement from molecules covalently attached to the plasmonic nanostructures, which provides a new way to high-sensitivity Raman sensing.
ISSN:1944-8244
1944-8252
DOI:10.1021/acsami.7b05959