The Intracellular Number of Magnetic Nanoparticles Modulates the Apoptotic Death Pathway after Magnetic Hyperthermia Treatment

Magnetic hyperthermia is a cancer treatment based on the exposure of magnetic nanoparticles to an alternating magnetic field in order to generate local heat. In this work, 3D cell culture models were prepared to observe the effect that a different number of internalized particles had on the mechanis...

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Bibliographic Details

Published in:	ACS applied materials & interfaces 2020-09, Vol.12 (39), p.43474-43487
Main Authors:	Beola, Lilianne, Asín, Laura, Roma-Rodrigues, Catarina, Fernández-Afonso, Yilian, Fratila, Raluca M, Serantes, David, Ruta, Sergiu, Chantrell, Roy W, Fernandes, Alexandra R, Baptista, Pedro V, de la Fuente, Jesús M, Grazú, Valeria, Gutiérrez, Lucía
Format:	Article
Language:	English
Subjects:	Animals Apoptosis - drug effects Biological and Medical Applications of Materials and Interfaces Cells, Cultured Hyperthermia, Induced Kinetics Macrophages - drug effects Magnetic Fields Magnetite Nanoparticles - chemistry Mice Monte Carlo Method Particle Size RAW 264.7 Cells Surface Properties
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