Immune Activation of RAW264.7 Macrophages by Low Molecular Weight Fucoidan Extracted from New Zealand Undaria pinnatifida

Fucoidan, a sulfated polysaccharide extracted from brown seaweeds, has been shown to possess various bioactivities. In particular, low molecular weight fucoidan (LMWF) has been shown to have better bioactivities. In this study, a LMWF (

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Bibliographic Details
Published in:Journal of agricultural and food chemistry 2018-10, Vol.66 (41), p.10721-10728
Main Authors: Bi, Decheng, Yu, Boming, Han, Qingguo, Lu, Jun, White, William Lindsey, Lai, Qiuxian, Cai, Nan, Luo, Wenqi, Gu, Liang, Li, Sheng, Xu, Hong, Hu, Zhangli, Nie, Shaoping, Xu, Xu
Format: Article
Language:English
Subjects:
Animals
Cell Survival - drug effects
Cytokines - metabolism
Humans
Macrophages - cytology
Macrophages - immunology
Mice
Mitogen-Activated Protein Kinase Kinases - metabolism
Molecular Weight
New Zealand
NF-kappa B - metabolism
Nitric Oxide - metabolism
Nitric Oxide Synthase Type II - metabolism
Polysaccharides - chemistry
Polysaccharides - isolation & purification
Polysaccharides - metabolism
RAW 264.7 Cells
Signal Transduction - drug effects
Undaria - chemistry
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Summary:Fucoidan, a sulfated polysaccharide extracted from brown seaweeds, has been shown to possess various bioactivities. In particular, low molecular weight fucoidan (LMWF) has been shown to have better bioactivities. In this study, a LMWF (
ISSN:0021-8561
1520-5118
DOI:10.1021/acs.jafc.8b03698