New approach to synthesis of 4-arylcoumarin derivatives

[Display omitted] A simple and highly efficient new approach for the synthesis of 4-aryl-2-oxo-2H-chromene-3-carbonitriles based on the oxidation and hydrolysis of 2-amino-4-aryl-4H-chromene-3-carbonitriles is described.

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Bibliographic Details
Published in:Tetrahedron letters 2015-10, Vol.56 (44), p.6145-6148
Main Authors: Bardasov, Ivan N., Alekseeva, Anastasiya U., Ershov, Oleg V., Surazhskaya, Marina D., Churakov, Andrei V., Grishanov, Dmitry A.
Format: Article
Language:English
Subjects:
Coumarin
Cyano compounds
Heterocyclic compounds
Knoevenagel condensation
Michael addition
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Description
Summary:[Display omitted] A simple and highly efficient new approach for the synthesis of 4-aryl-2-oxo-2H-chromene-3-carbonitriles based on the oxidation and hydrolysis of 2-amino-4-aryl-4H-chromene-3-carbonitriles is described.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2015.09.111