Differential diagnosis between pancreatic involvement in IgG4-related disease and pancreatic cancer

IgG4-related disease is a systemic disorder characterised by diffuse or tumoural inflammatory lesions. It can mimic pancreatic cancer, leading to increased rates of morbidity and mortality in patients as well as errors in diagnosis and treatment. The aim of this review is to take a differential diag...

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Bibliographic Details
Published in:	Gastroenterología y Hepatología (English Edition) 2021-02, Vol.44 (2), p.144-155
Main Authors:	Baenas, Diego Federico, Miretti, Virginia Soledad, Caeiro, Francisco, Paira, Sergio
Format:	Article
Language:	eng
Subjects:	Autoimmune pancreatitis Cáncer pancreático Enfermedad relacionada con IgG4 IgG4-related disease Pancreatic cancer Pancreatitis autoinmune
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Summary:	IgG4-related disease is a systemic disorder characterised by diffuse or tumoural inflammatory lesions. It can mimic pancreatic cancer, leading to increased rates of morbidity and mortality in patients as well as errors in diagnosis and treatment. The aim of this review is to take a differential diagnostic approach to these two entities using epidemiology, clinical and laboratory findings, imaging and histopathology. La enfermedad relacionada con IgG4 es un trastorno sistémico caracterizado por lesiones inflamatorias difusas o tumorales. Puede simular cáncer pancreático, condicionando un aumento en la morbimortalidad de los pacientes y errores diagnósticos y terapéuticos. El objetivo de esta revisión es realizar una aproximación diagnóstica diferencial de estas dos entidades, desde el punto de vista epidemiológico, clínico, analítico, imagenológico e histopatológico.
ISSN:	2444-3824