Lymphangiogenesis: Implications for Diagnosis, Treatment, and Prognosis in Patients With Melanoma

Lymphangiogenesis: Implications for Diagnosis, Treatment, and Prognosis in Patients With Melanoma

Abstract Disease course in melanoma often cannot be accurately predicted by means of the prognostic factors usually considered in patients with melanoma; therefore, new factors are clearly needed. Increasingly robust scientific evidence shows that tumor lymph vessels play a key role in melanoma that...

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Bibliographic Details
Published in:Actas dermo-sifiliográficas (English ed.) 2015-01, Vol.106 (1), p.7-16
Main Authors: Pastushenko, I, Conejero, C, Carapeto, F.J
Format: Article
Language:eng
Subjects:
Dermatology
Ganglio centinela
Humans
Internal Medicine
Linfangiogénesis
Lymphangiogenesis
Lymphatic Metastasis
Melanoma
Melanoma - diagnosis
Melanoma - pathology
Melanoma - secondary
Melanoma - therapy
Prognosis
Pronóstico
Sentinel Lymph Node
Skin Neoplasms - diagnosis
Skin Neoplasms - pathology
Skin Neoplasms - therapy
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Summary:Abstract Disease course in melanoma often cannot be accurately predicted by means of the prognostic factors usually considered in patients with melanoma; therefore, new factors are clearly needed. Increasingly robust scientific evidence shows that tumor lymph vessels play a key role in melanoma that metastasizes by lymphatic and hematogenous pathways. We review current knowledge and examine the implications of lymphangiogenesis in the diagnosis, treatment, and prognosis of patients with melanoma.
ISSN:1578-2190
1578-2190