Ectopic thyroid follicles in the submucosa of the duodenum

Ectopic microscopic thyroid follicles were encountered fortuitously in the submucosa of the duodenum in a 63-year-old man undergoing pancreaticoduodenectomy for pancreatic carcinoma. The follicles, filled with a colloid-like substance, were intermingled with Brunner's glands of the duodenum. Th...

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Bibliographic Details
Published in:Virchows Archiv A Pathological Anatomy and Histopathology 1991-01, Vol.418 (6), p.547-550
Main Authors: TAKAHASHI, T, ISHIKURA, H, KATO, H, TANABE, T, YOSHIKI, T
Format: Article
Language:English
Subjects:
Biological and medical sciences
Calcitonin - metabolism
Choristoma - metabolism
Choristoma - pathology
Duodenal Neoplasms - metabolism
Duodenal Neoplasms - pathology
Endocrinopathies
Humans
Immunohistochemistry
Intestinal Mucosa - metabolism
Intestinal Mucosa - pathology
Male
Medical sciences
Middle Aged
Thyroglobulin - metabolism
Thyroid Gland
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Summary:Ectopic microscopic thyroid follicles were encountered fortuitously in the submucosa of the duodenum in a 63-year-old man undergoing pancreaticoduodenectomy for pancreatic carcinoma. The follicles, filled with a colloid-like substance, were intermingled with Brunner's glands of the duodenum. There were no signs or symptoms of a thyroid tumour. The epithelial cells and colloid-like substance were both immunoreactive for thyroglobulin but no cells stained for calcitonin. The possibility of a metastatic origin for the follicles from an occult thyroid carcinoma was excluded by the clinical and histopathological findings. These ectopic thyroid follicles cannot be explained by developmental inclusions or metastasis and may be metaplastic in nature.
ISSN:0174-7398
1432-2307
DOI:10.1007/bf01606506