Incidence of type 1 (insulin-dependent) diabetes mellitus in subjects 0-14 years of age in the Comunidad of Madrid, Spain

A retrospective, population-based registry was established in the Comunidad of Madrid, Spain (total population: 4,780,572; under age 15: 1,105,243) to investigate the epidemiology of Type 1 (insulin-dependent) diabetes mellitus. Included were all cases diagnosed with diabetes between 1985 and 1988,...

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Bibliographic Details
Published in:Diabetologia 1990-07, Vol.33 (7), p.422-424
Main Authors: Serrano Ríos, M, Moy, C S, Martín Serrano, R, Minuesa Asensio, A, de Tomás Labat, M E, Zarandieta Romero, G, Herrera, J
Format: Article
Language:English
Subjects:
Adolescent
Age Factors
Child
Child, Preschool
Diabetes Mellitus, Type 1 - epidemiology
Female
Hospital Records
Humans
Incidence
Infant
Male
Registries
Retrospective Studies
Sex Factors
Spain
Urban Population
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Summary:A retrospective, population-based registry was established in the Comunidad of Madrid, Spain (total population: 4,780,572; under age 15: 1,105,243) to investigate the epidemiology of Type 1 (insulin-dependent) diabetes mellitus. Included were all cases diagnosed with diabetes between 1985 and 1988, with age onset less than 15 years, and using insulin at discharge from hospital. Using the capture-recapture method employing hospital records as the primary source and membership files of the Spanish Diabetic Association as the secondary source, the ascertainment was 90%. The overall annual incidence was estimated to be 11.3/100,000 (Poison 95% confidence interval: 10.3-12.4). There was no temporal increase in incidence, nor was there a significant sex difference in incidence rates, either overall or by year. The seasonal onset pattern showed the highest incidence in winter (December-February) and lowest in summer (June-August) (r = 7.36, p less than 0.05). The age-adjusted (world standard) incidence of 10.9/100,000 was inconsistent with the hypothesis of a north-south gradient in diabetes risk.
ISSN:0012-186X
1432-0428
DOI:10.1007/BF00404093