Automated determination of the right ventricular ejection fraction by digital processing of 81mKr scintigrams

A method is presented for the automated determination of the right ventricular ejection fraction (RVEF) by digital image processing of scintigrams obtained by intravenous infusion of Krypton 81m (81mKr) dissolved in a glucose solution. End-diastolic and end-systolic sum pictures were computed by the...

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Bibliographic Details
Published in:European Journal of Nuclear Medicine 1986, Vol.12 (5-6), p.231-235
Main Authors: ELFNER, R, VAKNINE, R, KNAPP, W. H, TILLMANNS, H, LORENZ, W. J
Format: Article
Language:English
Subjects:
Algorithms
Biological and medical sciences
Cardiomyopathy, Dilated - physiopathology
Cardiovascular system
Heart - diagnostic imaging
Humans
Image Processing, Computer-Assisted
Investigative techniques, diagnostic techniques (general aspects)
Krypton
Lung Diseases, Obstructive - physiopathology
Medical sciences
Radioisotopes
Radionuclide Imaging
Radionuclide investigations
Stroke Volume
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Summary:A method is presented for the automated determination of the right ventricular ejection fraction (RVEF) by digital image processing of scintigrams obtained by intravenous infusion of Krypton 81m (81mKr) dissolved in a glucose solution. End-diastolic and end-systolic sum pictures were computed by the addition of approximately 30-40 frames selected from the time-activity curve of a preliminary, manually drawn, right ventricular region of interest. After processing these two images with an adaptive Wiener filter, the right ventricular contour was determined by a recently developed algorithm using morphological and functional criteria. The RVEF was calculated for a series of 51 patients from the counts in the detected right ventricular regions in the end-diastolic and end-systolic sum images. In 16 patients without evidence of cardiopulmonary disease, the mean RVEF was 50 +/- 6.1%. RVEF was significantly reduced in 18 patients with obstructive pulmonary disease (42 +/- 6.5%) and in 17 patients with congestive cardiomyopathy (36 +/- 7.1%). The correlation coefficient between two determinations of the RVEF was r = 0.94. Through digital image processing, the determination of the RVEF by radioventriculography with 81m Kr showed high reliability and reproducibility.
ISSN:0340-6997
1619-7089
DOI:10.1007/BF00251975