Near‐Infrared‐Triggered On‐Demand Controlled Release of Adeno‐Associated Virus from Alginate Hydrogel Microbeads with Heat Transducer for Gene Therapy (Small 7/2023)

Alginate Hydrogel Microbeads In article number 2204139, Hiroaki Onoe and co‐workers present near‐infrared (NIR) triggered on‐demand adeno‐associated virus (AAV) release from alginate microbeads with heat transducer for gene therapy. The heat transducer encapsulated in microbeads generate heat under...

Full description

Saved in:
Bibliographic Details
Published in:Small (Weinheim an der Bergstrasse, Germany) Germany), 2023-02, Vol.19 (7), p.n/a
Main Authors: Takatsuka, Shuhei, Kubota, Takeshi, Kurashina, Yuta, Onoe, Hiroaki
Format: Article
Language:English
Subjects:
adeno‐associated viruses (AAVs)
alginate
gene therapies
hydrogel beads
near‐infrared
on‐demand DDS
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Alginate Hydrogel Microbeads In article number 2204139, Hiroaki Onoe and co‐workers present near‐infrared (NIR) triggered on‐demand adeno‐associated virus (AAV) release from alginate microbeads with heat transducer for gene therapy. The heat transducer encapsulated in microbeads generate heat under NIR‐irradiation. Subsequently, AAV release from the microbeads could be controlled on‐demand by the generated heat. In addition, the released AAV is gene‐transferred into cultured cell maintaining its activity.
ISSN:1613-6810
1613-6829
DOI:10.1002/smll.202370039