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A convenient synthesis of pyrazolo[3,4-d]pyrimidine-4,6-dione and pyrazolo[4,3-d]pyrimidine-5,7-dione derivatives

Pyrazolo‐[3,4‐d]pyrimidine‐4,6‐diones 5 and pyrazolo[4,3‐d]pyrimidine‐5,7‐diones 7 were synthesized by Curtius rearrangement of pyrazolic mono‐esters 2 and 3 followed by hetero‐cyclization via the ureas derivatives 4 and 6 under alkaline conditions.

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Bibliographic Details
Published in:Journal of heterocyclic chemistry 2000-09, Vol.37 (5), p.1247-1252
Main Authors: El Haddad, M., Soukri, M., Lazar, S., Bennamara, A., Guillaumet, G., Akssira, M.
Format: Article
Language:English
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Summary:Pyrazolo‐[3,4‐d]pyrimidine‐4,6‐diones 5 and pyrazolo[4,3‐d]pyrimidine‐5,7‐diones 7 were synthesized by Curtius rearrangement of pyrazolic mono‐esters 2 and 3 followed by hetero‐cyclization via the ureas derivatives 4 and 6 under alkaline conditions.
ISSN:0022-152X
1943-5193
DOI:10.1002/jhet.5570370536