Vitamin D, oral health, and disease characteristics in juvenile idiopathic arthritis: a multicenter cross-sectional study

Background Vitamin D deficiency has been associated with autoimmune diseases and oral health. Knowledge about the association between vitamin D status and oral conditions in JIA is limited. We aimed to investigate vitamin D status in a cohort of Norwegian children and adolescents with JIA and possib...

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Main Authors: Cetrelli, Lena Elisabet, Bletsa, Athanasia, Lundestad, Anette, Gil, Elisabeth Grut, Fischer, Johannes Maria, Halbig, Josefine Mareile, Frid, Paula Hanna Therese, Angenete, Oskar W, Lien, Ingrid Lillevoll, Rosén, Annika, Tylleskär, Karin, Luukko, Keijo, Nordal, Ellen Berit, Åstrøm, Anne-Kristine N, Skeie, Marit Slåttelid, Feuerherm, Astrid Jullumstrø, Sen, Abhijit, Rygg, Marite
Format: Article
Language:English
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Summary:Background Vitamin D deficiency has been associated with autoimmune diseases and oral health. Knowledge about the association between vitamin D status and oral conditions in JIA is limited. We aimed to investigate vitamin D status in a cohort of Norwegian children and adolescents with JIA and possible associations between serum vitamin D levels, clinical indicators of oral health, and JIA disease characteristics. Methods This multi-center, cross-sectional study, included individuals with JIA aged 4–16 years from three geographically spread regions in Norway. Demographic data, age at disease onset, disease duration, JIA category, disease status, medication, and vitamin D intake were registered. One blood sample per individual was analyzed for 25(OH) vitamin D, and the level of insufficiency was defined as