aPKC l/λ a potential target for the therapy of Hh-dependent and Smo-inhibitor-resistant advanced BCC

Basal cell carcinoma （BCC）, a skin cancer, is the most common malignancy in white people [1, 2]. Although mor-tality is low as BCC rarely metastasizes, people suffering from BCC are at high risk of developing other malignancies [3]. Given its low metastatic potential, treatment of BCC focuses on loc...

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Bibliographic Details
Published in:生物化学与生物物理学报：英文版 2013 (7), p.610-611
Main Author: Xiangdong Lv Lin Fu Yun Zhao
Format: Article
Language:English
Subjects:
BCC
Smo
恶性肿瘤
抑制剂
治疗
皮肤癌
菌相
螺杆
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Summary:Basal cell carcinoma （BCC）, a skin cancer, is the most common malignancy in white people [1, 2]. Although mor-tality is low as BCC rarely metastasizes, people suffering from BCC are at high risk of developing other malignancies [3]. Given its low metastatic potential, treatment of BCC focuses on local control, including surgical and non-surgical measures [3, 4]. In the best hands, the 5-year cure rates of ex-cision, curettage and cautery, and cryosurgery are 95% or higher [3].
ISSN:1672-9145
1745-7270