Serum-free process development: improving the yield and consistency of human mesenchymal stem cell production

Background: The cost effective production of hMSCs for off-the-shelf and patient specific therapies will require an increasing focus on improving product yield and driving manufacturing consistency. Methods: Bone-marrow derived hMSCs from two donors were expanded for 36 days in monolayer with medium...

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Bibliographic Details
Main Authors: Thomas Heathman, Alexandra Stolzing, Claire Fabian, Qasim A. Rafiq, Alvin W. Nienow, Karen Coopman, Bo Kara, Christopher J. Hewitt
Format: Default Article
Published: 2015
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Online Access:https://hdl.handle.net/2134/18932
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