Human induced pluripotent stem cells generate light responsive retinal organoids with variable and nutrient dependent efficiency

The availability of in vitro models of the human retina in which to perform pharmacological and toxicological studies is an urgent and unmet need. An essential step for developing in vitro models of human retina is the ability to generate laminated, physiologically functional and light-responsive re...

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Main Authors: Dean Hallam, Gerrit Hilgen, Birthe Dorgau, Lili Zhu, Min Yu, Sanja Bojic, Philip Hewitt, Michael Schmitt, Marianne Uteng, Stefan Kustermann, David Steel, Mike Nicholds, Rob Thomas, Achim Treumann, Andrew Porter, Evelyne Sernagor, Lyle Armstrong, Majlinda Lako
Format: Default Article
Published: 2018
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Online Access:https://hdl.handle.net/2134/34320
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