Electrospun polycaprolactone nano-fibers supports growth of human mesenchymal stem cells

Electrospun polycaprolactone nano-fibers supports growth of human mesenchymal stem cells

Electrospun polycaprolactone (PCL) layers with sub-micron fibres arranged in random, semi-aligned and aligned manners were prepared and their anisotropic mechanical property were further characterised at various stretching angle. Proof of principle study was carried out to assess biocompatibility of...

Full description

Saved in:
Bibliographic Details
Main Authors: Andrea Fotticchia, Yang Liu, Emrah Demirci, Cristina Lenardi
Format: Default Conference proceeding
Published: 2013
Subjects:
Mechanical engineering not elsewhere classified
untagged
Mechanical Engineering not elsewhere classified
Online Access:https://hdl.handle.net/2134/14023
Tags: Add Tag
No Tags, Be the first to tag this record!
id rr-article-9559646
record_format Figshare
spelling rr-article-95596462013-01-01T00:00:00Z Electrospun polycaprolactone nano-fibers supports growth of human mesenchymal stem cells Andrea Fotticchia (7204088) Yang Liu (1257603) Emrah Demirci (1256556) Cristina Lenardi (204065) Mechanical engineering not elsewhere classified untagged Mechanical Engineering not elsewhere classified Electrospun polycaprolactone (PCL) layers with sub-micron fibres arranged in random, semi-aligned and aligned manners were prepared and their anisotropic mechanical property were further characterised at various stretching angle. Proof of principle study was carried out to assess biocompatibility of electrospun layers with human mesenchymal stem cells (hMSCs). Cell adhesion, viability and orientation outcomes showed that aligned PCL nano-fibers can be applied as a template to guide the alignment of hMSCs and could be a promising scaffold for tissue engineering of anisotropic annulus fibrosus in spinal inter-vertebral disc. 2013-01-01T00:00:00Z Text Conference contribution 2134/14023 https://figshare.com/articles/conference_contribution/Electrospun_polycaprolactone_nano-fibers_supports_growth_of_human_mesenchymal_stem_cells/9559646 CC BY-NC-ND 4.0
institution Loughborough University
collection Figshare
topic Mechanical engineering not elsewhere classified
untagged
Mechanical Engineering not elsewhere classified
spellingShingle Mechanical engineering not elsewhere classified
untagged
Mechanical Engineering not elsewhere classified
Andrea Fotticchia
Yang Liu
Emrah Demirci
Cristina Lenardi
Electrospun polycaprolactone nano-fibers supports growth of human mesenchymal stem cells
description Electrospun polycaprolactone (PCL) layers with sub-micron fibres arranged in random, semi-aligned and aligned manners were prepared and their anisotropic mechanical property were further characterised at various stretching angle. Proof of principle study was carried out to assess biocompatibility of electrospun layers with human mesenchymal stem cells (hMSCs). Cell adhesion, viability and orientation outcomes showed that aligned PCL nano-fibers can be applied as a template to guide the alignment of hMSCs and could be a promising scaffold for tissue engineering of anisotropic annulus fibrosus in spinal inter-vertebral disc.
format Default
Conference proceeding
author Andrea Fotticchia
Yang Liu
Emrah Demirci
Cristina Lenardi
author_facet Andrea Fotticchia
Yang Liu
Emrah Demirci
Cristina Lenardi
author_sort Andrea Fotticchia (7204088)
title Electrospun polycaprolactone nano-fibers supports growth of human mesenchymal stem cells
title_short Electrospun polycaprolactone nano-fibers supports growth of human mesenchymal stem cells
title_full Electrospun polycaprolactone nano-fibers supports growth of human mesenchymal stem cells
title_fullStr Electrospun polycaprolactone nano-fibers supports growth of human mesenchymal stem cells
title_full_unstemmed Electrospun polycaprolactone nano-fibers supports growth of human mesenchymal stem cells
title_sort electrospun polycaprolactone nano-fibers supports growth of human mesenchymal stem cells
publishDate 2013
url https://hdl.handle.net/2134/14023
_version_ 1797376476300967936

Similar Items