Continuous flow ozonolysis using atmospheric plasma

Ozonolysis is widely used in organic synthesis to obtain aldehydes and ketones from alkenes, a process of great interest, for example, for the pharmaceutical industry. This reaction is more environmentally accepted than other alternative oxidations and it has good atom efficiency. Ozonolysis, howeve...

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Main Authors: Carlos Castello Beltran, Benjamin R. Buckley, Felipe Iza
Format: Default Conference proceeding
Published: 2012
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Online Access:https://hdl.handle.net/2134/17568
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spelling rr-article-95559022012-01-01T00:00:00Z Continuous flow ozonolysis using atmospheric plasma Carlos Castello Beltran (7165145) Benjamin R. Buckley (1299393) Felipe Iza (1258965) Mechanical engineering not elsewhere classified untagged Mechanical Engineering not elsewhere classified Ozonolysis is widely used in organic synthesis to obtain aldehydes and ketones from alkenes, a process of great interest, for example, for the pharmaceutical industry. This reaction is more environmentally accepted than other alternative oxidations and it has good atom efficiency. Ozonolysis, however, has an important drawback; the ozonides generated as intermediates in the process are unstable and pose a risk of explosion. To minimize this risk, continuous flow processing can be used, as this eliminates the accumulation of large amounts of hazardous intermediates, thereby offering an alternative to batch processing that greatly enhances the control and safety of the ozonolysis process.1,2 Here we report on the results obtained with an air plasma-driven continuous-flow ozonolysis system. (... continues) 2012-01-01T00:00:00Z Text Conference contribution 2134/17568 https://figshare.com/articles/conference_contribution/Continuous_flow_ozonolysis_using_atmospheric_plasma/9555902 CC BY-NC-ND 4.0
institution Loughborough University
collection Figshare
topic Mechanical engineering not elsewhere classified
untagged
Mechanical Engineering not elsewhere classified
spellingShingle Mechanical engineering not elsewhere classified
untagged
Mechanical Engineering not elsewhere classified
Carlos Castello Beltran
Benjamin R. Buckley
Felipe Iza
Continuous flow ozonolysis using atmospheric plasma
description Ozonolysis is widely used in organic synthesis to obtain aldehydes and ketones from alkenes, a process of great interest, for example, for the pharmaceutical industry. This reaction is more environmentally accepted than other alternative oxidations and it has good atom efficiency. Ozonolysis, however, has an important drawback; the ozonides generated as intermediates in the process are unstable and pose a risk of explosion. To minimize this risk, continuous flow processing can be used, as this eliminates the accumulation of large amounts of hazardous intermediates, thereby offering an alternative to batch processing that greatly enhances the control and safety of the ozonolysis process.1,2 Here we report on the results obtained with an air plasma-driven continuous-flow ozonolysis system. (... continues)
format Default
Conference proceeding
author Carlos Castello Beltran
Benjamin R. Buckley
Felipe Iza
author_facet Carlos Castello Beltran
Benjamin R. Buckley
Felipe Iza
author_sort Carlos Castello Beltran (7165145)
title Continuous flow ozonolysis using atmospheric plasma
title_short Continuous flow ozonolysis using atmospheric plasma
title_full Continuous flow ozonolysis using atmospheric plasma
title_fullStr Continuous flow ozonolysis using atmospheric plasma
title_full_unstemmed Continuous flow ozonolysis using atmospheric plasma
title_sort continuous flow ozonolysis using atmospheric plasma
publishDate 2012
url https://hdl.handle.net/2134/17568
_version_ 1797918576582066176