Cold atmospheric-pressure plasma treatment for promotion of cell adhesion onto PDMS substrates

This research aims to develop a cell coating on polydimethylsiloxane (PDMS) to study the response of corneal epithelial cells to mechanical stress. PDMS is a highly hydrophobic silicone elastomer, which despite its excellent mechanical properties is an unattractive surface for cell adhesion. In orde...

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Bibliographic Details
Main Authors: P. Puntambekar, Alexander H. Shaw, Yang Liu, Felipe Iza
Format: Default Conference proceeding
Published: 2015
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Online Access:https://hdl.handle.net/2134/18418
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Summary:This research aims to develop a cell coating on polydimethylsiloxane (PDMS) to study the response of corneal epithelial cells to mechanical stress. PDMS is a highly hydrophobic silicone elastomer, which despite its excellent mechanical properties is an unattractive surface for cell adhesion. In order to promote cell adhesion onto PDMS, a cold atmospheric-pressure plasma treatment has been used to modify the surface properties of the PDMS without affecting its bulk mechanical characteristics.