Age-related striatal BOLD changes without changes in behavioral loss aversion

Loss aversion (LA), the idea that negative valuations have a higher psychological impact than positive ones, is considered an important variable in consumer research. The literature on aging and behavior suggests older individuals may show more LA, although it is not clear if this is an effect of ag...

Full description

Saved in:

Bibliographic Details
Main Authors:	Vijay Viswanathan, Sang Lee, Jodi M. Gilman, Byoung Woo Kim, Nick Lee, Laura Chamberlain, Sherri L. Livengood, Kalyan Raman, Myung Joo Lee, Jake Kuster, Daniel B. Stern, Bobby Calder, Frank J. Mulhern, Anne J. Blood, Hans C. Breiter
Format:	Default Article
Published:	2015
Subjects:	Other commerce, management, tourism and services not elsewhere classified Loss aversion Aging Nucleus accumbens Reward FMRI Neurocompensation Business and Management not elsewhere classified
Online Access:	https://hdl.handle.net/2134/18630
Tags:	Add Tag No Tags, Be the first to tag this record!

id	rr-article-9505028
record_format	Figshare
spelling	rr-article-95050282015-01-01T00:00:00Z Age-related striatal BOLD changes without changes in behavioral loss aversion Vijay Viswanathan (314324) Sang Lee (236493) Jodi M. Gilman (7200041) Byoung Woo Kim (7200044) Nick Lee (1254072) Laura Chamberlain (7198724) Sherri L. Livengood (7200047) Kalyan Raman (7200050) Myung Joo Lee (7200053) Jake Kuster (7200056) Daniel B. Stern (7200059) Bobby Calder (7200062) Frank J. Mulhern (7200065) Anne J. Blood (7200068) Hans C. Breiter (7200071) Other commerce, management, tourism and services not elsewhere classified Loss aversion Aging Nucleus accumbens Reward FMRI Neurocompensation Business and Management not elsewhere classified Loss aversion (LA), the idea that negative valuations have a higher psychological impact than positive ones, is considered an important variable in consumer research. The literature on aging and behavior suggests older individuals may show more LA, although it is not clear if this is an effect of aging in general (as in the continuum from age 20 and 50 years), or of the state of older age (e.g., past age 65 years). We also have not yet identified the potential biological effects of aging on the neural processing of LA. In the current study we used a cohort of subjects with a 30 year range of ages, and performed whole brain functional MRI (fMRI) to examine the ventral striatum/nucleus accumbens (VS/NAc) response during a passive viewing of affective faces with model-based fMRI analysis incorporating behavioral data from a validated approach/avoidance task with the same stimuli. Our a priorifocus on the VS/NAc was based on (1) the VS/NAc being a central region for reward/aversion processing; (2) its activation to both positive and negative stimuli; (3) its reported involvement with tracking LA. LA from approach/avoidance to affective faces showed excellent fidelity to published measures of LA. Imaging results were then compared to the behavioral measure of LA using the same affective faces. Although there was no relationship between age and LA, we observed increasing neural differential sensitivity (NDS) of the VS/NAc to avoidance responses (negative valuations) relative to approach responses (positive valuations) with increasing age. These findings suggest that a central region for reward/aversion processing changes with age, and may require more activation to produce the same LA behavior as in younger individuals, consistent with the idea of neural efficiency observed with high IQ individuals showing less brain activation to complete the same task. 2015-01-01T00:00:00Z Text Journal contribution 2134/18630 https://figshare.com/articles/journal_contribution/Age-related_striatal_BOLD_changes_without_changes_in_behavioral_loss_aversion/9505028 CC BY-NC-ND 4.0
institution	Loughborough University
collection	Figshare
topic	Other commerce, management, tourism and services not elsewhere classified Loss aversion Aging Nucleus accumbens Reward FMRI Neurocompensation Business and Management not elsewhere classified
spellingShingle	Other commerce, management, tourism and services not elsewhere classified Loss aversion Aging Nucleus accumbens Reward FMRI Neurocompensation Business and Management not elsewhere classified Vijay Viswanathan Sang Lee Jodi M. Gilman Byoung Woo Kim Nick Lee Laura Chamberlain Sherri L. Livengood Kalyan Raman Myung Joo Lee Jake Kuster Daniel B. Stern Bobby Calder Frank J. Mulhern Anne J. Blood Hans C. Breiter Age-related striatal BOLD changes without changes in behavioral loss aversion
description	Loss aversion (LA), the idea that negative valuations have a higher psychological impact than positive ones, is considered an important variable in consumer research. The literature on aging and behavior suggests older individuals may show more LA, although it is not clear if this is an effect of aging in general (as in the continuum from age 20 and 50 years), or of the state of older age (e.g., past age 65 years). We also have not yet identified the potential biological effects of aging on the neural processing of LA. In the current study we used a cohort of subjects with a 30 year range of ages, and performed whole brain functional MRI (fMRI) to examine the ventral striatum/nucleus accumbens (VS/NAc) response during a passive viewing of affective faces with model-based fMRI analysis incorporating behavioral data from a validated approach/avoidance task with the same stimuli. Our a priorifocus on the VS/NAc was based on (1) the VS/NAc being a central region for reward/aversion processing; (2) its activation to both positive and negative stimuli; (3) its reported involvement with tracking LA. LA from approach/avoidance to affective faces showed excellent fidelity to published measures of LA. Imaging results were then compared to the behavioral measure of LA using the same affective faces. Although there was no relationship between age and LA, we observed increasing neural differential sensitivity (NDS) of the VS/NAc to avoidance responses (negative valuations) relative to approach responses (positive valuations) with increasing age. These findings suggest that a central region for reward/aversion processing changes with age, and may require more activation to produce the same LA behavior as in younger individuals, consistent with the idea of neural efficiency observed with high IQ individuals showing less brain activation to complete the same task.
format	Default Article
author	Vijay Viswanathan Sang Lee Jodi M. Gilman Byoung Woo Kim Nick Lee Laura Chamberlain Sherri L. Livengood Kalyan Raman Myung Joo Lee Jake Kuster Daniel B. Stern Bobby Calder Frank J. Mulhern Anne J. Blood Hans C. Breiter
author_facet	Vijay Viswanathan Sang Lee Jodi M. Gilman Byoung Woo Kim Nick Lee Laura Chamberlain Sherri L. Livengood Kalyan Raman Myung Joo Lee Jake Kuster Daniel B. Stern Bobby Calder Frank J. Mulhern Anne J. Blood Hans C. Breiter
author_sort	Vijay Viswanathan (314324)
title	Age-related striatal BOLD changes without changes in behavioral loss aversion
title_short	Age-related striatal BOLD changes without changes in behavioral loss aversion
title_full	Age-related striatal BOLD changes without changes in behavioral loss aversion
title_fullStr	Age-related striatal BOLD changes without changes in behavioral loss aversion
title_full_unstemmed	Age-related striatal BOLD changes without changes in behavioral loss aversion
title_sort	age-related striatal bold changes without changes in behavioral loss aversion
publishDate	2015
url	https://hdl.handle.net/2134/18630
_version_	1796649767328022528

Age-related striatal BOLD changes without changes in behavioral loss aversion

Similar Items