Enzymatic fluorination of biotin and tetrazine conjugates for pretargeting approaches to positron emission tomography imaging
The use of radiolabelled antibodies and antibody-derived recombinant constructs has shown promise for both imaging and therapeutic use. In this context, the biotin–avidin/streptavidin pairing, along with the inverse-electron-demand Diels–Alder (iEDDA) reaction, have found application in pretargeting...
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Main Authors: | , , , , |
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Format: | Default Article |
Published: |
2018
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Online Access: | https://hdl.handle.net/2134/36580 |
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