Systematic microcarrier screening and agitated culture conditions improves human mesenchymal stem cell yield in bioreactors
Production of human mesenchymal stem cells for allogeneic cell therapies requires scalable, cost-effective manufacturing processes. Microcarriers enable the culture of anchorage-dependent cells in stirred-tank bioreactors. However, no robust, transferable methodology for microcarrier selection exist...
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Main Authors: | Qasim A. Rafiq, Karen Coopman, Alvin W. Nienow, Christopher J. Hewitt |
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Format: | Default Article |
Published: |
2016
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Online Access: | https://hdl.handle.net/2134/19978 |
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