Selective ablation of primary and paracrine senescent cells by targeting iron dyshomeostasis

Senescent cells can spread the senescent phenotype to other cells by secreting senescence-associated secretory phenotype factors. The resulting paracrine senescent cells make a significant contribution to the burden of senescent cell accumulation with age. Previous efforts made to characterize parac...

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Bibliographic Details
Main Authors: Tesfahun Dessale Admasu, Kristie Kim, Michael Rae, Roberto Avelar, Ryan L Gonciarz, Abdelhadi Rebbaa, João Pedro de Magalhães, Adam R Renslo, Alexandra Stolzing, Amit Sharma
Format: Default Article
Published: 2023
Subjects:
Biochemistry and cell biology
Medical physiology
senescence
paracrine senescence
ferroptosis
prodrug
iron
ferrous
Online Access:https://hdl.handle.net/2134/22109996.v1
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https://hdl.handle.net/2134/22109996.v1

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