Evaluating preservative efficacy in pharmaceutical and cosmetic products

In 1965 the Royal Swedish Medical Board reported high levels of microbial contamination in nan-sterile drug products not normally required to be sterile (Kallings and Enerfeldt, 1965], Since then a number of surveys have confirmed these findings in both pharmaceutical and cosmetic products e.g. Schi...

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Main Author: K.E. Moore
Format: Default Thesis
Published: 2022
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Online Access:https://dx.doi.org/10.26174/thesis.lboro.20036525.v1
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spelling rr-article-200365252022-06-09T08:21:33Z Evaluating preservative efficacy in pharmaceutical and cosmetic products K.E. Moore (8377264) Other chemical sciences not elsewhere classified Evaluation Preservative efficacy Pharmaceutical Cosmetics Chemical Sciences not elsewhere classified <p>In 1965 the Royal Swedish Medical Board reported high levels of microbial contamination in nan-sterile drug products not normally required to be sterile (Kallings and Enerfeldt, 1965], Since then a number of surveys have confirmed these findings in both pharmaceutical and cosmetic products e.g. Schiller et.al. ( 1968], Anon (1971 a],Bowman, White and Lyles ( 1971), Westwood (1971), Kruger (1973).</p> <p>Microbial contamination of such products is undesirable because it can cause spoilage of the preparation and pose a health hazard to the user ( Bruch, 1972). Various regulatory bodies have imposed or advised limits on the types and/or numbers of organisms that are undesirable (Engel, 1967) Bruch 1971, 1972; Anon 1972, 1975b). Methods to monitor contamination have been published (Allwood, 1971; Kruger, 1973; British Pharmacopoeia, 1973; Anon, 1975b, 1976, United States Pharmacopoeia, XIX revision, 1975) and guides to good manufacturing practices produced (Anon, 1975a, 1975b).</p> 2022-06-09T08:21:33Z Text Thesis 10.26174/thesis.lboro.20036525.v1 https://figshare.com/articles/thesis/Evaluating_preservative_efficacy_in_pharmaceutical_and_cosmetic_products/20036525 CC BY-NC-ND 4.0
institution Loughborough University
collection Figshare
topic Other chemical sciences not elsewhere classified
Evaluation
Preservative efficacy
Pharmaceutical
Cosmetics
Chemical Sciences not elsewhere classified
spellingShingle Other chemical sciences not elsewhere classified
Evaluation
Preservative efficacy
Pharmaceutical
Cosmetics
Chemical Sciences not elsewhere classified
K.E. Moore
Evaluating preservative efficacy in pharmaceutical and cosmetic products
description In 1965 the Royal Swedish Medical Board reported high levels of microbial contamination in nan-sterile drug products not normally required to be sterile (Kallings and Enerfeldt, 1965], Since then a number of surveys have confirmed these findings in both pharmaceutical and cosmetic products e.g. Schiller et.al. ( 1968], Anon (1971 a],Bowman, White and Lyles ( 1971), Westwood (1971), Kruger (1973). Microbial contamination of such products is undesirable because it can cause spoilage of the preparation and pose a health hazard to the user ( Bruch, 1972). Various regulatory bodies have imposed or advised limits on the types and/or numbers of organisms that are undesirable (Engel, 1967) Bruch 1971, 1972; Anon 1972, 1975b). Methods to monitor contamination have been published (Allwood, 1971; Kruger, 1973; British Pharmacopoeia, 1973; Anon, 1975b, 1976, United States Pharmacopoeia, XIX revision, 1975) and guides to good manufacturing practices produced (Anon, 1975a, 1975b).
format Default
Thesis
author K.E. Moore
author_facet K.E. Moore
author_sort K.E. Moore (8377264)
title Evaluating preservative efficacy in pharmaceutical and cosmetic products
title_short Evaluating preservative efficacy in pharmaceutical and cosmetic products
title_full Evaluating preservative efficacy in pharmaceutical and cosmetic products
title_fullStr Evaluating preservative efficacy in pharmaceutical and cosmetic products
title_full_unstemmed Evaluating preservative efficacy in pharmaceutical and cosmetic products
title_sort evaluating preservative efficacy in pharmaceutical and cosmetic products
publishDate 2022
url https://dx.doi.org/10.26174/thesis.lboro.20036525.v1
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