The mitochondrial genome in aging and disease and the future of mitochondrial therapeutics

Mitochondria are intracellular organelles that utilize nutrients to generate energy in the form of ATP by oxidative phosphorylation. Mitochondrial DNA (mtDNA) in humans is a 16,569 base pair double-stranded circular DNA that encodes for 13 vital proteins of the electron transport chain. Our understa...

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Bibliographic Details
Main Authors: Sanjana Saravanan, Caitlin J Lewis, Bhavna Dixit, Matthew S O’Connor, Alexandra Stolzing, Amutha Boominathan
Format: Default Article
Published: 2022
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Online Access:https://hdl.handle.net/2134/19234950.v1
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