Urinary albumin excretion rate： a risk factor for retinal hard exudates in macular region in type 2 diabetic patients

Background The various risk factors for retinal hard exudates are still poorly understood in type 2 diabetic patients.The aim of this study was to determine the association between urinary albumin excretion rate （UAER） and hard exudates in macular region in north Chinese patients.Methods A total of...

Full description

Saved in:
Bibliographic Details
Published in:Chinese medical journal 2014, Vol.127 (12), p.2293-2298
Main Authors: Wang, Shaocheng, Lin, Siyong, Cao, Xi, Zheng, Yuezhong, Wang, Jinyang, Lu, Na, Yang, Jinkui
Format: Article
Language:English
Subjects:
2型糖尿病
Aged
Albuminuria - physiopathology
Diabetes Mellitus, Type 2 - physiopathology
Diabetes Mellitus, Type 2 - urine
Female
Humans
Logistic回归分析
Macular Edema - physiopathology
Macular Edema - urine
Male
Middle Aged
Retrospective Studies
Risk Factors
危险因素
排泄率
渗出
白蛋白
硬性
视网膜
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by
cites cdi_FETCH-LOGICAL-c378t-5d9de50e1f01bc6f5a7cc113937a3354ea18ab984ff138e259c58efde5b7633f3
container_end_page 2298
container_issue 12
container_start_page 2293
container_title Chinese medical journal
container_volume 127
creator Wang, Shaocheng
Lin, Siyong
Cao, Xi
Zheng, Yuezhong
Wang, Jinyang
Lu, Na
Yang, Jinkui
description Background The various risk factors for retinal hard exudates are still poorly understood in type 2 diabetic patients.The aim of this study was to determine the association between urinary albumin excretion rate （UAER） and hard exudates in macular region in north Chinese patients.Methods A total of 272 patients （272 eyes） were enrolled for this study,including 154 subjects from group 1 （mild hard exudates）,91 subjects from group 2 （moderate hard exudates） and 27 subjects from group 3 （severe hard exudates） confirmed using colour fundus photography,optical coherence tomography （OCT） as well as slit-lamp biomicroscopy with 78 diopter （D） lens.Each participant underwent a comprehensive assessment that included biochemical,clinical characteristics test and detailed ophthalmic evaluation.One-way analysis of variance （ANOVA） test and chi-square test were performed to analyze the fasting blood glucose （FBG）,glycated hemoglobin （HbA1c）,total cholesterol （TC）,low density lipoprotein （LDL）,high density lipoprotein （HDL）,triglycerides （TG）,full blood counts,urinary albumin excretion rate （UAER）,blood creatinine （CREA）,duration of diabetes,body mass index （BMI）,systolic blood pressures （SBP） and diastolic blood pressures （DBP） between groups.Ordinal logistic regression analysis was further performed in order to eliminating the possible confounding factors.Results Three groups were matched in terms of age and gender.Risk factors which showed significant difference between groups include FBG （P ＜0.001）,HbA1c （P ＜0.001）,LDL （P ＜0.001）,UAER （P ＜0.001）,duration of diabetes （P=0.001）,TC （P=0.005）,SBP （P=0.026）,CREA （P=0.004） and haemoglobin （Hb） （P=0.012）.There was no significant difference between groups for the TG,HDL,DBP,platelet,total white blood cells and BMI.Using ordinal Logistic regression analyses,of all the variables,HbA1c,LDL and UAER which were independent risk factor for hard exudates showed a significantly odds ratio of 1.25,3.07,and 1.39,respectively.There were also significant differences in UAER level between patients with mild,moderate,severe hard exudates groups （P ＜0.001）.Conclusions UAER was an independent risk factor associated with retinal hard exudates in macular region in type 2 diabetic patients.This study highlights the need for close monitoring and fundus examination for hard exudates in patients with elevated UAER to prevent irreversible visual loss.
doi_str_mv 10.3760/cma.j.issn.0366-6999.20140327
format article
fullrecord <record><control><sourceid>wanfang_jour_proqu</sourceid><recordid>TN_cdi_wanfang_journals_zhcmj201412018</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><cqvip_id>661620356</cqvip_id><wanfj_id>zhcmj201412018</wanfj_id><sourcerecordid>zhcmj201412018</sourcerecordid><originalsourceid>FETCH-LOGICAL-c378t-5d9de50e1f01bc6f5a7cc113937a3354ea18ab984ff138e259c58efde5b7633f3</originalsourceid><addsrcrecordid>eNo9kc9O3DAQh60KVBbaV6gsJKpeEvwndpIDB4TaUgmJC5ytiWPvOk2cxU5E6aP0WXinvgKOdpeDbcn6fjOj-RC6oCTnpSSXeoC8y12MPidcykzWdZ0zQgvCWfkBrZgoWCZkQY_Q6h04QacxdoQwIUr5EZ2wouaUFWKFnh-D8xBeMPTNPDiPzR8dzORGjwNM5v_rPww4uPgbW9DTGLBNZwE89HgDoU2BuU1kxCk8gJ57WID1UiH9TC9bgxluHTQppPEWJmf8FD-hYwt9NJ_37xl6_PH94eY2u7v_-evm-i7TvKymTLR1awQx1BLaaGkFlFpTymteAueiMEAraOqqsJbyyjBRa1EZmzJNKTm3_Ax93dV9Bm_Br1U3ziHNHtXfjR66ZXE0XVUCv-3AbRifZhMnNbioTd-DN-McFRVpmZXglCT0aofqMMYYjFXb4Ia0REWJWiSpJEl1apGkFgdqcaAOklL-y77V3AymfU8frCTgfN9gM_r1k0tjHxgpqWSEC8nfAOnknrQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1536685310</pqid></control><display><type>article</type><title>Urinary albumin excretion rate： a risk factor for retinal hard exudates in macular region in type 2 diabetic patients</title><source>HEAL-Link subscriptions: Lippincott Williams &amp; Wilkins</source><creator>Wang, Shaocheng ; Lin, Siyong ; Cao, Xi ; Zheng, Yuezhong ; Wang, Jinyang ; Lu, Na ; Yang, Jinkui</creator><creatorcontrib>Wang, Shaocheng ; Lin, Siyong ; Cao, Xi ; Zheng, Yuezhong ; Wang, Jinyang ; Lu, Na ; Yang, Jinkui</creatorcontrib><description>Background The various risk factors for retinal hard exudates are still poorly understood in type 2 diabetic patients.The aim of this study was to determine the association between urinary albumin excretion rate （UAER） and hard exudates in macular region in north Chinese patients.Methods A total of 272 patients （272 eyes） were enrolled for this study,including 154 subjects from group 1 （mild hard exudates）,91 subjects from group 2 （moderate hard exudates） and 27 subjects from group 3 （severe hard exudates） confirmed using colour fundus photography,optical coherence tomography （OCT） as well as slit-lamp biomicroscopy with 78 diopter （D） lens.Each participant underwent a comprehensive assessment that included biochemical,clinical characteristics test and detailed ophthalmic evaluation.One-way analysis of variance （ANOVA） test and chi-square test were performed to analyze the fasting blood glucose （FBG）,glycated hemoglobin （HbA1c）,total cholesterol （TC）,low density lipoprotein （LDL）,high density lipoprotein （HDL）,triglycerides （TG）,full blood counts,urinary albumin excretion rate （UAER）,blood creatinine （CREA）,duration of diabetes,body mass index （BMI）,systolic blood pressures （SBP） and diastolic blood pressures （DBP） between groups.Ordinal logistic regression analysis was further performed in order to eliminating the possible confounding factors.Results Three groups were matched in terms of age and gender.Risk factors which showed significant difference between groups include FBG （P ＜0.001）,HbA1c （P ＜0.001）,LDL （P ＜0.001）,UAER （P ＜0.001）,duration of diabetes （P=0.001）,TC （P=0.005）,SBP （P=0.026）,CREA （P=0.004） and haemoglobin （Hb） （P=0.012）.There was no significant difference between groups for the TG,HDL,DBP,platelet,total white blood cells and BMI.Using ordinal Logistic regression analyses,of all the variables,HbA1c,LDL and UAER which were independent risk factor for hard exudates showed a significantly odds ratio of 1.25,3.07,and 1.39,respectively.There were also significant differences in UAER level between patients with mild,moderate,severe hard exudates groups （P ＜0.001）.Conclusions UAER was an independent risk factor associated with retinal hard exudates in macular region in type 2 diabetic patients.This study highlights the need for close monitoring and fundus examination for hard exudates in patients with elevated UAER to prevent irreversible visual loss.</description><identifier>ISSN: 0366-6999</identifier><identifier>EISSN: 2542-5641</identifier><identifier>DOI: 10.3760/cma.j.issn.0366-6999.20140327</identifier><identifier>PMID: 24931245</identifier><language>eng</language><publisher>China: Department of Endocrinology,Beijing Tongren Hospital,Capital Medical University,Beijng Key Laboratory of Diabetes Research and Care,Beijing 100730,China%Clinical College of Ophthalmology,Tianjin Medical University,Tianjin Eye Hospital,Tianjin 300070,China</publisher><subject>2型糖尿病 ; Aged ; Albuminuria - physiopathology ; Diabetes Mellitus, Type 2 - physiopathology ; Diabetes Mellitus, Type 2 - urine ; Female ; Humans ; Logistic回归分析 ; Macular Edema - physiopathology ; Macular Edema - urine ; Male ; Middle Aged ; Retrospective Studies ; Risk Factors ; 危险因素 ; 排泄率 ; 渗出 ; 白蛋白 ; 硬性 ; 视网膜</subject><ispartof>Chinese medical journal, 2014, Vol.127 (12), p.2293-2298</ispartof><rights>Copyright © Wanfang Data Co. Ltd. All Rights Reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c378t-5d9de50e1f01bc6f5a7cc113937a3354ea18ab984ff138e259c58efde5b7633f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/85656X/85656X.jpg</thumbnail><link.rule.ids>315,786,790,4043,27956,27957,27958</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24931245$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wang, Shaocheng</creatorcontrib><creatorcontrib>Lin, Siyong</creatorcontrib><creatorcontrib>Cao, Xi</creatorcontrib><creatorcontrib>Zheng, Yuezhong</creatorcontrib><creatorcontrib>Wang, Jinyang</creatorcontrib><creatorcontrib>Lu, Na</creatorcontrib><creatorcontrib>Yang, Jinkui</creatorcontrib><title>Urinary albumin excretion rate： a risk factor for retinal hard exudates in macular region in type 2 diabetic patients</title><title>Chinese medical journal</title><addtitle>Chinese Medical Journal</addtitle><description>Background The various risk factors for retinal hard exudates are still poorly understood in type 2 diabetic patients.The aim of this study was to determine the association between urinary albumin excretion rate （UAER） and hard exudates in macular region in north Chinese patients.Methods A total of 272 patients （272 eyes） were enrolled for this study,including 154 subjects from group 1 （mild hard exudates）,91 subjects from group 2 （moderate hard exudates） and 27 subjects from group 3 （severe hard exudates） confirmed using colour fundus photography,optical coherence tomography （OCT） as well as slit-lamp biomicroscopy with 78 diopter （D） lens.Each participant underwent a comprehensive assessment that included biochemical,clinical characteristics test and detailed ophthalmic evaluation.One-way analysis of variance （ANOVA） test and chi-square test were performed to analyze the fasting blood glucose （FBG）,glycated hemoglobin （HbA1c）,total cholesterol （TC）,low density lipoprotein （LDL）,high density lipoprotein （HDL）,triglycerides （TG）,full blood counts,urinary albumin excretion rate （UAER）,blood creatinine （CREA）,duration of diabetes,body mass index （BMI）,systolic blood pressures （SBP） and diastolic blood pressures （DBP） between groups.Ordinal logistic regression analysis was further performed in order to eliminating the possible confounding factors.Results Three groups were matched in terms of age and gender.Risk factors which showed significant difference between groups include FBG （P ＜0.001）,HbA1c （P ＜0.001）,LDL （P ＜0.001）,UAER （P ＜0.001）,duration of diabetes （P=0.001）,TC （P=0.005）,SBP （P=0.026）,CREA （P=0.004） and haemoglobin （Hb） （P=0.012）.There was no significant difference between groups for the TG,HDL,DBP,platelet,total white blood cells and BMI.Using ordinal Logistic regression analyses,of all the variables,HbA1c,LDL and UAER which were independent risk factor for hard exudates showed a significantly odds ratio of 1.25,3.07,and 1.39,respectively.There were also significant differences in UAER level between patients with mild,moderate,severe hard exudates groups （P ＜0.001）.Conclusions UAER was an independent risk factor associated with retinal hard exudates in macular region in type 2 diabetic patients.This study highlights the need for close monitoring and fundus examination for hard exudates in patients with elevated UAER to prevent irreversible visual loss.</description><subject>2型糖尿病</subject><subject>Aged</subject><subject>Albuminuria - physiopathology</subject><subject>Diabetes Mellitus, Type 2 - physiopathology</subject><subject>Diabetes Mellitus, Type 2 - urine</subject><subject>Female</subject><subject>Humans</subject><subject>Logistic回归分析</subject><subject>Macular Edema - physiopathology</subject><subject>Macular Edema - urine</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>危险因素</subject><subject>排泄率</subject><subject>渗出</subject><subject>白蛋白</subject><subject>硬性</subject><subject>视网膜</subject><issn>0366-6999</issn><issn>2542-5641</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><recordid>eNo9kc9O3DAQh60KVBbaV6gsJKpeEvwndpIDB4TaUgmJC5ytiWPvOk2cxU5E6aP0WXinvgKOdpeDbcn6fjOj-RC6oCTnpSSXeoC8y12MPidcykzWdZ0zQgvCWfkBrZgoWCZkQY_Q6h04QacxdoQwIUr5EZ2wouaUFWKFnh-D8xBeMPTNPDiPzR8dzORGjwNM5v_rPww4uPgbW9DTGLBNZwE89HgDoU2BuU1kxCk8gJ57WID1UiH9TC9bgxluHTQppPEWJmf8FD-hYwt9NJ_37xl6_PH94eY2u7v_-evm-i7TvKymTLR1awQx1BLaaGkFlFpTymteAueiMEAraOqqsJbyyjBRa1EZmzJNKTm3_Ax93dV9Bm_Br1U3ziHNHtXfjR66ZXE0XVUCv-3AbRifZhMnNbioTd-DN-McFRVpmZXglCT0aofqMMYYjFXb4Ia0REWJWiSpJEl1apGkFgdqcaAOklL-y77V3AymfU8frCTgfN9gM_r1k0tjHxgpqWSEC8nfAOnknrQ</recordid><startdate>2014</startdate><enddate>2014</enddate><creator>Wang, Shaocheng</creator><creator>Lin, Siyong</creator><creator>Cao, Xi</creator><creator>Zheng, Yuezhong</creator><creator>Wang, Jinyang</creator><creator>Lu, Na</creator><creator>Yang, Jinkui</creator><general>Department of Endocrinology,Beijing Tongren Hospital,Capital Medical University,Beijng Key Laboratory of Diabetes Research and Care,Beijing 100730,China%Clinical College of Ophthalmology,Tianjin Medical University,Tianjin Eye Hospital,Tianjin 300070,China</general><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>W91</scope><scope>~WA</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>2B.</scope><scope>4A8</scope><scope>92I</scope><scope>93N</scope><scope>PSX</scope><scope>TCJ</scope></search><sort><creationdate>2014</creationdate><title>Urinary albumin excretion rate： a risk factor for retinal hard exudates in macular region in type 2 diabetic patients</title><author>Wang, Shaocheng ; Lin, Siyong ; Cao, Xi ; Zheng, Yuezhong ; Wang, Jinyang ; Lu, Na ; Yang, Jinkui</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c378t-5d9de50e1f01bc6f5a7cc113937a3354ea18ab984ff138e259c58efde5b7633f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>2型糖尿病</topic><topic>Aged</topic><topic>Albuminuria - physiopathology</topic><topic>Diabetes Mellitus, Type 2 - physiopathology</topic><topic>Diabetes Mellitus, Type 2 - urine</topic><topic>Female</topic><topic>Humans</topic><topic>Logistic回归分析</topic><topic>Macular Edema - physiopathology</topic><topic>Macular Edema - urine</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>危险因素</topic><topic>排泄率</topic><topic>渗出</topic><topic>白蛋白</topic><topic>硬性</topic><topic>视网膜</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wang, Shaocheng</creatorcontrib><creatorcontrib>Lin, Siyong</creatorcontrib><creatorcontrib>Cao, Xi</creatorcontrib><creatorcontrib>Zheng, Yuezhong</creatorcontrib><creatorcontrib>Wang, Jinyang</creatorcontrib><creatorcontrib>Lu, Na</creatorcontrib><creatorcontrib>Yang, Jinkui</creatorcontrib><collection>维普_期刊</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>维普中文期刊数据库</collection><collection>中文科技期刊数据库-医药卫生</collection><collection>中文科技期刊数据库- 镜像站点</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Wanfang Data Journals - Hong Kong</collection><collection>WANFANG Data Centre</collection><collection>Wanfang Data Journals</collection><collection>万方数据期刊 - 香港版</collection><collection>China Online Journals (COJ)</collection><collection>China Online Journals (COJ)</collection><jtitle>Chinese medical journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wang, Shaocheng</au><au>Lin, Siyong</au><au>Cao, Xi</au><au>Zheng, Yuezhong</au><au>Wang, Jinyang</au><au>Lu, Na</au><au>Yang, Jinkui</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Urinary albumin excretion rate： a risk factor for retinal hard exudates in macular region in type 2 diabetic patients</atitle><jtitle>Chinese medical journal</jtitle><addtitle>Chinese Medical Journal</addtitle><date>2014</date><risdate>2014</risdate><volume>127</volume><issue>12</issue><spage>2293</spage><epage>2298</epage><pages>2293-2298</pages><issn>0366-6999</issn><eissn>2542-5641</eissn><notes>exudates; macular edema; albuminuia; risk factors; diabetes mellitus</notes><notes>11-2154/R</notes><notes>Background The various risk factors for retinal hard exudates are still poorly understood in type 2 diabetic patients.The aim of this study was to determine the association between urinary albumin excretion rate （UAER） and hard exudates in macular region in north Chinese patients.Methods A total of 272 patients （272 eyes） were enrolled for this study,including 154 subjects from group 1 （mild hard exudates）,91 subjects from group 2 （moderate hard exudates） and 27 subjects from group 3 （severe hard exudates） confirmed using colour fundus photography,optical coherence tomography （OCT） as well as slit-lamp biomicroscopy with 78 diopter （D） lens.Each participant underwent a comprehensive assessment that included biochemical,clinical characteristics test and detailed ophthalmic evaluation.One-way analysis of variance （ANOVA） test and chi-square test were performed to analyze the fasting blood glucose （FBG）,glycated hemoglobin （HbA1c）,total cholesterol （TC）,low density lipoprotein （LDL）,high density lipoprotein （HDL）,triglycerides （TG）,full blood counts,urinary albumin excretion rate （UAER）,blood creatinine （CREA）,duration of diabetes,body mass index （BMI）,systolic blood pressures （SBP） and diastolic blood pressures （DBP） between groups.Ordinal logistic regression analysis was further performed in order to eliminating the possible confounding factors.Results Three groups were matched in terms of age and gender.Risk factors which showed significant difference between groups include FBG （P ＜0.001）,HbA1c （P ＜0.001）,LDL （P ＜0.001）,UAER （P ＜0.001）,duration of diabetes （P=0.001）,TC （P=0.005）,SBP （P=0.026）,CREA （P=0.004） and haemoglobin （Hb） （P=0.012）.There was no significant difference between groups for the TG,HDL,DBP,platelet,total white blood cells and BMI.Using ordinal Logistic regression analyses,of all the variables,HbA1c,LDL and UAER which were independent risk factor for hard exudates showed a significantly odds ratio of 1.25,3.07,and 1.39,respectively.There were also significant differences in UAER level between patients with mild,moderate,severe hard exudates groups （P ＜0.001）.Conclusions UAER was an independent risk factor associated with retinal hard exudates in macular region in type 2 diabetic patients.This study highlights the need for close monitoring and fundus examination for hard exudates in patients with elevated UAER to prevent irreversible visual loss.</notes><notes>ObjectType-Article-1</notes><notes>SourceType-Scholarly Journals-1</notes><notes>ObjectType-Feature-2</notes><notes>content type line 23</notes><abstract>Background The various risk factors for retinal hard exudates are still poorly understood in type 2 diabetic patients.The aim of this study was to determine the association between urinary albumin excretion rate （UAER） and hard exudates in macular region in north Chinese patients.Methods A total of 272 patients （272 eyes） were enrolled for this study,including 154 subjects from group 1 （mild hard exudates）,91 subjects from group 2 （moderate hard exudates） and 27 subjects from group 3 （severe hard exudates） confirmed using colour fundus photography,optical coherence tomography （OCT） as well as slit-lamp biomicroscopy with 78 diopter （D） lens.Each participant underwent a comprehensive assessment that included biochemical,clinical characteristics test and detailed ophthalmic evaluation.One-way analysis of variance （ANOVA） test and chi-square test were performed to analyze the fasting blood glucose （FBG）,glycated hemoglobin （HbA1c）,total cholesterol （TC）,low density lipoprotein （LDL）,high density lipoprotein （HDL）,triglycerides （TG）,full blood counts,urinary albumin excretion rate （UAER）,blood creatinine （CREA）,duration of diabetes,body mass index （BMI）,systolic blood pressures （SBP） and diastolic blood pressures （DBP） between groups.Ordinal logistic regression analysis was further performed in order to eliminating the possible confounding factors.Results Three groups were matched in terms of age and gender.Risk factors which showed significant difference between groups include FBG （P ＜0.001）,HbA1c （P ＜0.001）,LDL （P ＜0.001）,UAER （P ＜0.001）,duration of diabetes （P=0.001）,TC （P=0.005）,SBP （P=0.026）,CREA （P=0.004） and haemoglobin （Hb） （P=0.012）.There was no significant difference between groups for the TG,HDL,DBP,platelet,total white blood cells and BMI.Using ordinal Logistic regression analyses,of all the variables,HbA1c,LDL and UAER which were independent risk factor for hard exudates showed a significantly odds ratio of 1.25,3.07,and 1.39,respectively.There were also significant differences in UAER level between patients with mild,moderate,severe hard exudates groups （P ＜0.001）.Conclusions UAER was an independent risk factor associated with retinal hard exudates in macular region in type 2 diabetic patients.This study highlights the need for close monitoring and fundus examination for hard exudates in patients with elevated UAER to prevent irreversible visual loss.</abstract><cop>China</cop><pub>Department of Endocrinology,Beijing Tongren Hospital,Capital Medical University,Beijng Key Laboratory of Diabetes Research and Care,Beijing 100730,China%Clinical College of Ophthalmology,Tianjin Medical University,Tianjin Eye Hospital,Tianjin 300070,China</pub><pmid>24931245</pmid><doi>10.3760/cma.j.issn.0366-6999.20140327</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0366-6999
ispartof Chinese medical journal, 2014, Vol.127 (12), p.2293-2298
issn 0366-6999
2542-5641
language eng
recordid cdi_wanfang_journals_zhcmj201412018
source HEAL-Link subscriptions: Lippincott Williams & Wilkins
subjects 2型糖尿病
Aged
Albuminuria - physiopathology
Diabetes Mellitus, Type 2 - physiopathology
Diabetes Mellitus, Type 2 - urine
Female
Humans
Logistic回归分析
Macular Edema - physiopathology
Macular Edema - urine
Male
Middle Aged
Retrospective Studies
Risk Factors
危险因素
排泄率
渗出
白蛋白
硬性
视网膜
title Urinary albumin excretion rate： a risk factor for retinal hard exudates in macular region in type 2 diabetic patients
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-09-22T16%3A29%3A16IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-wanfang_jour_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Urinary%20albumin%20excretion%20rate%EF%BC%9A%20a%20risk%20factor%20for%20retinal%20hard%20exudates%20in%20macular%20region%20in%20type%202%20diabetic%20patients&rft.jtitle=Chinese%20medical%20journal&rft.au=Wang,%20Shaocheng&rft.date=2014&rft.volume=127&rft.issue=12&rft.spage=2293&rft.epage=2298&rft.pages=2293-2298&rft.issn=0366-6999&rft.eissn=2542-5641&rft_id=info:doi/10.3760/cma.j.issn.0366-6999.20140327&rft_dat=%3Cwanfang_jour_proqu%3Ezhcmj201412018%3C/wanfang_jour_proqu%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c378t-5d9de50e1f01bc6f5a7cc113937a3354ea18ab984ff138e259c58efde5b7633f3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1536685310&rft_id=info:pmid/24931245&rft_cqvip_id=661620356&rft_wanfj_id=zhcmj201412018&rfr_iscdi=true