An AUG codon upstream of rev and env open reading frames ensures optimal translation of the simian immunodeficiency virus Env protein

Abstract The mRNAs encoding the Rev and Env proteins of simian immunodeficiency virus (SIV) are unique because upstream translation start codons are present that may modulate the expression of these viral proteins. We previously reported the regulatory effect of a small upstream open reading frame (...

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Bibliographic Details

Published in:	Virology (New York, N.Y.) N.Y.), 2013-02, Vol.436 (1), p.191-200
Main Authors:	van der Velden, Gisela J, Vink, Monique A, Klaver, Bep, Das, Atze T, Berkhout, Ben
Format:	Article
Language:	eng
Subjects:	Cell Line Codon, Initiator Gene Expression Regulation, Viral Gene Products, env - genetics Gene Products, rev - genetics Genes, env Genes, rev HEK293 Cells Humans Infectious Disease mRNA translation Mutation Open Reading Frames Polycistronic mRNA Protein Biosynthesis Regulation of gene expression RNA, Messenger - genetics RNA, Messenger - metabolism Simian immunodeficiency virus Simian Immunodeficiency Virus - genetics Simian Immunodeficiency Virus - metabolism SIV Upstream AUG codons
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