Loading…
Cerebellum and psychiatric disorders
The objective of this update article is to report structural and functional neuroimaging studies exploring the potential role of cerebellum in the pathophysiology of psychiatric disorders. A non-systematic literature review was conducted by means of Medline using the following terms as a parameter:...
Saved in:
| Published in: | Revista brasileira de psiquiatria 2008-09, Vol.30 (3), p.281-289 |
|---|---|
| Main Authors: | , , , |
| Format: | Article |
| Language: | eng ; por |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c519t-5f5856bdd28339f6070c8c562fb31f9bfc77bf3d94263e258dbeb3e7c92ed7a03 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c519t-5f5856bdd28339f6070c8c562fb31f9bfc77bf3d94263e258dbeb3e7c92ed7a03 |
| container_end_page | 289 |
| container_issue | 3 |
| container_start_page | 281 |
| container_title | Revista brasileira de psiquiatria |
| container_volume | 30 |
| creator | Baldaçara, Leonardo Borgio, João Guilherme Fiorani Lacerda, Acioly Luiz Tavares de Jackowski, Andrea Parolin |
| description | The objective of this update article is to report structural and functional neuroimaging studies exploring the potential role of cerebellum in the pathophysiology of psychiatric disorders.
A non-systematic literature review was conducted by means of Medline using the following terms as a parameter: "cerebellum", "cerebellar vermis", "schizophrenia", "bipolar disorder", "depression", "anxiety disorders", "dementia" and "attention deficit hyperactivity disorder". The electronic search was done up to April 2008.
Structural and functional cerebellar abnormalities have been reported in many psychiatric disorders, namely schizophrenia, bipolar disorder, major depressive disorder, anxiety disorders, dementia and attention deficit hyperactivity disorder. Structural magnetic resonance imaging studies have reported smaller total cerebellar and vermal volumes in schizophrenia, mood disorders and attention deficit hyperactivity disorder. Functional magnetic resonance imaging studies using cognitive paradigms have shown alterations in cerebellar activity in schizophrenia, anxiety disorders and attention deficit hyperactivity disorder. In dementia, the cerebellum is affected in later stages of the disease.
Contrasting with early theories, cerebellum appears to play a major role in different brain functions other than balance and motor control, including emotional regulation and cognition. Future studies are clearly needed to further elucidate the role of cerebellum in both normal and pathological behavior, mood regulation, and cognitive functioning. |
| doi_str_mv | 10.1590/s1516-44462008000300016 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_sciel</sourceid><recordid>TN_cdi_scielo_journals_S1516_44462008000300016</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><scielo_id>S1516_44462008000300016</scielo_id><sourcerecordid>69627882</sourcerecordid><originalsourceid>FETCH-LOGICAL-c519t-5f5856bdd28339f6070c8c562fb31f9bfc77bf3d94263e258dbeb3e7c92ed7a03</originalsourceid><addsrcrecordid>eNp9UMtKAzEUDaLYWv0F7ULcTb1JJq-lFF9QcKGCuzBJbnDKTKcmnUX_3imtuBBcXM5dnAfnEHJFYUaFgdtMBZVFWZaSAWgA4MNReUTGVIMpSsE-jof_hzQiZzkvAZjiWp2SEdWa85LDmFzPMaHDpunbabUK03Xe-s-62qTaT0OduxQw5XNyEqsm48UBJ-T94f5t_lQsXh6f53eLwgtqNoWIQgvpQmCDu4kSFHjthWTRcRqNi14pF3kwJZMcmdDBoeOovGEYVAV8QmZ73-xrbDq77Pq0GgLt666J_VN3ENzsBevUffWYN7atsx_aVCvs-mylkUxpzQai2hN96nJOGO061W2VtpaC3S36T8TlIaJ3LYZf3WFC_g1Q0G3J</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>69627882</pqid></control><display><type>article</type><title>Cerebellum and psychiatric disorders</title><source>SciELO Brazil</source><creator>Baldaçara, Leonardo ; Borgio, João Guilherme Fiorani ; Lacerda, Acioly Luiz Tavares de ; Jackowski, Andrea Parolin</creator><creatorcontrib>Baldaçara, Leonardo ; Borgio, João Guilherme Fiorani ; Lacerda, Acioly Luiz Tavares de ; Jackowski, Andrea Parolin</creatorcontrib><description>The objective of this update article is to report structural and functional neuroimaging studies exploring the potential role of cerebellum in the pathophysiology of psychiatric disorders.
A non-systematic literature review was conducted by means of Medline using the following terms as a parameter: "cerebellum", "cerebellar vermis", "schizophrenia", "bipolar disorder", "depression", "anxiety disorders", "dementia" and "attention deficit hyperactivity disorder". The electronic search was done up to April 2008.
Structural and functional cerebellar abnormalities have been reported in many psychiatric disorders, namely schizophrenia, bipolar disorder, major depressive disorder, anxiety disorders, dementia and attention deficit hyperactivity disorder. Structural magnetic resonance imaging studies have reported smaller total cerebellar and vermal volumes in schizophrenia, mood disorders and attention deficit hyperactivity disorder. Functional magnetic resonance imaging studies using cognitive paradigms have shown alterations in cerebellar activity in schizophrenia, anxiety disorders and attention deficit hyperactivity disorder. In dementia, the cerebellum is affected in later stages of the disease.
Contrasting with early theories, cerebellum appears to play a major role in different brain functions other than balance and motor control, including emotional regulation and cognition. Future studies are clearly needed to further elucidate the role of cerebellum in both normal and pathological behavior, mood regulation, and cognitive functioning.</description><identifier>ISSN: 1516-4446</identifier><identifier>ISSN: 1809-452X</identifier><identifier>EISSN: 1809-452X</identifier><identifier>EISSN: 1516-4446</identifier><identifier>DOI: 10.1590/s1516-44462008000300016</identifier><identifier>PMID: 18833430</identifier><language>eng ; por</language><publisher>Brazil: Associação Brasileira de Psiquiatria</publisher><subject>Anxiety Disorders - pathology ; Anxiety Disorders - physiopathology ; Attention Deficit Disorder with Hyperactivity - pathology ; Attention Deficit Disorder with Hyperactivity - physiopathology ; Cerebellum - pathology ; Cerebellum - physiopathology ; Dementia - pathology ; Dementia - physiopathology ; Humans ; Magnetic Resonance Imaging ; Mental Disorders - pathology ; Mental Disorders - physiopathology ; Mood Disorders - pathology ; Mood Disorders - physiopathology ; PSYCHIATRY ; Schizophrenia - pathology ; Schizophrenia - physiopathology</subject><ispartof>Revista brasileira de psiquiatria, 2008-09, Vol.30 (3), p.281-289</ispartof><rights>This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c519t-5f5856bdd28339f6070c8c562fb31f9bfc77bf3d94263e258dbeb3e7c92ed7a03</citedby><cites>FETCH-LOGICAL-c519t-5f5856bdd28339f6070c8c562fb31f9bfc77bf3d94263e258dbeb3e7c92ed7a03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,315,786,790,891,24178,27957,27958</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18833430$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Baldaçara, Leonardo</creatorcontrib><creatorcontrib>Borgio, João Guilherme Fiorani</creatorcontrib><creatorcontrib>Lacerda, Acioly Luiz Tavares de</creatorcontrib><creatorcontrib>Jackowski, Andrea Parolin</creatorcontrib><title>Cerebellum and psychiatric disorders</title><title>Revista brasileira de psiquiatria</title><addtitle>Braz J Psychiatry</addtitle><description>The objective of this update article is to report structural and functional neuroimaging studies exploring the potential role of cerebellum in the pathophysiology of psychiatric disorders.
A non-systematic literature review was conducted by means of Medline using the following terms as a parameter: "cerebellum", "cerebellar vermis", "schizophrenia", "bipolar disorder", "depression", "anxiety disorders", "dementia" and "attention deficit hyperactivity disorder". The electronic search was done up to April 2008.
Structural and functional cerebellar abnormalities have been reported in many psychiatric disorders, namely schizophrenia, bipolar disorder, major depressive disorder, anxiety disorders, dementia and attention deficit hyperactivity disorder. Structural magnetic resonance imaging studies have reported smaller total cerebellar and vermal volumes in schizophrenia, mood disorders and attention deficit hyperactivity disorder. Functional magnetic resonance imaging studies using cognitive paradigms have shown alterations in cerebellar activity in schizophrenia, anxiety disorders and attention deficit hyperactivity disorder. In dementia, the cerebellum is affected in later stages of the disease.
Contrasting with early theories, cerebellum appears to play a major role in different brain functions other than balance and motor control, including emotional regulation and cognition. Future studies are clearly needed to further elucidate the role of cerebellum in both normal and pathological behavior, mood regulation, and cognitive functioning.</description><subject>Anxiety Disorders - pathology</subject><subject>Anxiety Disorders - physiopathology</subject><subject>Attention Deficit Disorder with Hyperactivity - pathology</subject><subject>Attention Deficit Disorder with Hyperactivity - physiopathology</subject><subject>Cerebellum - pathology</subject><subject>Cerebellum - physiopathology</subject><subject>Dementia - pathology</subject><subject>Dementia - physiopathology</subject><subject>Humans</subject><subject>Magnetic Resonance Imaging</subject><subject>Mental Disorders - pathology</subject><subject>Mental Disorders - physiopathology</subject><subject>Mood Disorders - pathology</subject><subject>Mood Disorders - physiopathology</subject><subject>PSYCHIATRY</subject><subject>Schizophrenia - pathology</subject><subject>Schizophrenia - physiopathology</subject><issn>1516-4446</issn><issn>1809-452X</issn><issn>1809-452X</issn><issn>1516-4446</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><recordid>eNp9UMtKAzEUDaLYWv0F7ULcTb1JJq-lFF9QcKGCuzBJbnDKTKcmnUX_3imtuBBcXM5dnAfnEHJFYUaFgdtMBZVFWZaSAWgA4MNReUTGVIMpSsE-jof_hzQiZzkvAZjiWp2SEdWa85LDmFzPMaHDpunbabUK03Xe-s-62qTaT0OduxQw5XNyEqsm48UBJ-T94f5t_lQsXh6f53eLwgtqNoWIQgvpQmCDu4kSFHjthWTRcRqNi14pF3kwJZMcmdDBoeOovGEYVAV8QmZ73-xrbDq77Pq0GgLt666J_VN3ENzsBevUffWYN7atsx_aVCvs-mylkUxpzQai2hN96nJOGO061W2VtpaC3S36T8TlIaJ3LYZf3WFC_g1Q0G3J</recordid><startdate>200809</startdate><enddate>200809</enddate><creator>Baldaçara, Leonardo</creator><creator>Borgio, João Guilherme Fiorani</creator><creator>Lacerda, Acioly Luiz Tavares de</creator><creator>Jackowski, Andrea Parolin</creator><general>Associação Brasileira de Psiquiatria</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>GPN</scope></search><sort><creationdate>200809</creationdate><title>Cerebellum and psychiatric disorders</title><author>Baldaçara, Leonardo ; Borgio, João Guilherme Fiorani ; Lacerda, Acioly Luiz Tavares de ; Jackowski, Andrea Parolin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c519t-5f5856bdd28339f6070c8c562fb31f9bfc77bf3d94263e258dbeb3e7c92ed7a03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng ; por</language><creationdate>2008</creationdate><topic>Anxiety Disorders - pathology</topic><topic>Anxiety Disorders - physiopathology</topic><topic>Attention Deficit Disorder with Hyperactivity - pathology</topic><topic>Attention Deficit Disorder with Hyperactivity - physiopathology</topic><topic>Cerebellum - pathology</topic><topic>Cerebellum - physiopathology</topic><topic>Dementia - pathology</topic><topic>Dementia - physiopathology</topic><topic>Humans</topic><topic>Magnetic Resonance Imaging</topic><topic>Mental Disorders - pathology</topic><topic>Mental Disorders - physiopathology</topic><topic>Mood Disorders - pathology</topic><topic>Mood Disorders - physiopathology</topic><topic>PSYCHIATRY</topic><topic>Schizophrenia - pathology</topic><topic>Schizophrenia - physiopathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Baldaçara, Leonardo</creatorcontrib><creatorcontrib>Borgio, João Guilherme Fiorani</creatorcontrib><creatorcontrib>Lacerda, Acioly Luiz Tavares de</creatorcontrib><creatorcontrib>Jackowski, Andrea Parolin</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>SciELO</collection><jtitle>Revista brasileira de psiquiatria</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Baldaçara, Leonardo</au><au>Borgio, João Guilherme Fiorani</au><au>Lacerda, Acioly Luiz Tavares de</au><au>Jackowski, Andrea Parolin</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cerebellum and psychiatric disorders</atitle><jtitle>Revista brasileira de psiquiatria</jtitle><addtitle>Braz J Psychiatry</addtitle><date>2008-09</date><risdate>2008</risdate><volume>30</volume><issue>3</issue><spage>281</spage><epage>289</epage><pages>281-289</pages><issn>1516-4446</issn><issn>1809-452X</issn><eissn>1809-452X</eissn><eissn>1516-4446</eissn><notes>SourceType-Scholarly Journals-1</notes><notes>ObjectType-Feature-4</notes><notes>ObjectType-Undefined-1</notes><notes>content type line 23</notes><notes>ObjectType-Review-2</notes><notes>ObjectType-Article-3</notes><abstract>The objective of this update article is to report structural and functional neuroimaging studies exploring the potential role of cerebellum in the pathophysiology of psychiatric disorders.
A non-systematic literature review was conducted by means of Medline using the following terms as a parameter: "cerebellum", "cerebellar vermis", "schizophrenia", "bipolar disorder", "depression", "anxiety disorders", "dementia" and "attention deficit hyperactivity disorder". The electronic search was done up to April 2008.
Structural and functional cerebellar abnormalities have been reported in many psychiatric disorders, namely schizophrenia, bipolar disorder, major depressive disorder, anxiety disorders, dementia and attention deficit hyperactivity disorder. Structural magnetic resonance imaging studies have reported smaller total cerebellar and vermal volumes in schizophrenia, mood disorders and attention deficit hyperactivity disorder. Functional magnetic resonance imaging studies using cognitive paradigms have shown alterations in cerebellar activity in schizophrenia, anxiety disorders and attention deficit hyperactivity disorder. In dementia, the cerebellum is affected in later stages of the disease.
Contrasting with early theories, cerebellum appears to play a major role in different brain functions other than balance and motor control, including emotional regulation and cognition. Future studies are clearly needed to further elucidate the role of cerebellum in both normal and pathological behavior, mood regulation, and cognitive functioning.</abstract><cop>Brazil</cop><pub>Associação Brasileira de Psiquiatria</pub><pmid>18833430</pmid><doi>10.1590/s1516-44462008000300016</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1516-4446 |
| ispartof | Revista brasileira de psiquiatria, 2008-09, Vol.30 (3), p.281-289 |
| issn | 1516-4446 1809-452X 1809-452X 1516-4446 |
| language | eng ; por |
| recordid | cdi_scielo_journals_S1516_44462008000300016 |
| source | SciELO Brazil |
| subjects | Anxiety Disorders - pathology Anxiety Disorders - physiopathology Attention Deficit Disorder with Hyperactivity - pathology Attention Deficit Disorder with Hyperactivity - physiopathology Cerebellum - pathology Cerebellum - physiopathology Dementia - pathology Dementia - physiopathology Humans Magnetic Resonance Imaging Mental Disorders - pathology Mental Disorders - physiopathology Mood Disorders - pathology Mood Disorders - physiopathology PSYCHIATRY Schizophrenia - pathology Schizophrenia - physiopathology |
| title | Cerebellum and psychiatric disorders |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-09-22T19%3A20%3A37IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_sciel&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Cerebellum%20and%20psychiatric%20disorders&rft.jtitle=Revista%20brasileira%20de%20psiquiatria&rft.au=Balda%C3%A7ara,%20Leonardo&rft.date=2008-09&rft.volume=30&rft.issue=3&rft.spage=281&rft.epage=289&rft.pages=281-289&rft.issn=1516-4446&rft.eissn=1809-452X&rft_id=info:doi/10.1590/s1516-44462008000300016&rft_dat=%3Cproquest_sciel%3E69627882%3C/proquest_sciel%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c519t-5f5856bdd28339f6070c8c562fb31f9bfc77bf3d94263e258dbeb3e7c92ed7a03%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=69627882&rft_id=info:pmid/18833430&rft_scielo_id=S1516_44462008000300016&rfr_iscdi=true |