Loading…
Diagnostic accuracy of menstrual blood for human papillomavirus detection in cervical cancer screening: a systematic review
Globally, cervical cancer is the fourth most common cancer among females and a major public health problem in low- and middle-income countries (LMICs). There are several screening tests available for cervical cancer screening; however, due to a lack of organised screening facilities as well as facto...
Saved in:
Published in: | Ecancermedicalscience 2022-07, Vol.16, p.1427-1427 |
---|---|
Main Authors: | , , , , , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that cite this one |
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
cited_by | cdi_FETCH-LOGICAL-c404t-57b47529ff8a9797fa2d1b81eab9f19f0eb407dc01ba79b03041daf5cf3878fa3 |
---|---|
cites | |
container_end_page | 1427 |
container_issue | |
container_start_page | 1427 |
container_title | Ecancermedicalscience |
container_volume | 16 |
creator | Chakravarti, Priyal Maheshwari, Amita Tahlan, Shweta Kadam, Prithviraj Bagal, Sonali Gore, Suvarna Panse, Nandkumar Deodhar, Kedar Chaturvedi, Pankaj Dikshit, Rajesh Budukh, Atul |
description | Globally, cervical cancer is the fourth most common cancer among females and a major public health problem in low- and middle-income countries (LMICs). There are several screening tests available for cervical cancer screening; however, due to a lack of organised screening facilities as well as factors such as low participation rates in screening programmes, many women die due to cervical cancer. To reach out to a large number of women, an easy, non-invasive and time-saving screening method is required. Evidence supports that cervical cancer screening with human papillomavirus deoxyribonucleic acid (HPV DNA) testing is the most effective technique for lowering the incidence and mortality associated with cervical cancer when compared to other screening methods. Furthermore, a small number of studies have reported that menstrual blood can be used as an alternative sample for HPV detection for cervical cancer screening. We have done a systematic review of the studies that have reported the diagnostic accuracy of menstrual blood to detect HPV. We found five studies in our literature search. The studies showed the diagnostic accuracy of menstrual blood in terms of sensitivity ranging from 82.8% to 97.7% and specificity ranging from 50.0% to 98.0% in cervical intraepithelial neoplasia or HPV infection detection. This review supports the use of menstrual blood as a screening tool for cervical cancer especially in LMICs where women are reluctant to participate in cervical cancer screening due to issues such as embarrassment and discomfort to test procedures as well as busy schedules. However, further studies are required to compare the diagnostic accuracy of menstrual blood in detecting HPV compared to other self-sampled HPV detection methods. This is one of the methods that can be explored further for use as a cervical cancer screening test. |
doi_str_mv | 10.3332/ecancer.2022.1427 |
format | article |
fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9458266</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2719671745</sourcerecordid><originalsourceid>FETCH-LOGICAL-c404t-57b47529ff8a9797fa2d1b81eab9f19f0eb407dc01ba79b03041daf5cf3878fa3</originalsourceid><addsrcrecordid>eNpdkc1q3DAUhUVpaX7aB-hO0E03M5FkybK6CIQ0P4VAN-1aXMtXEwVbmkr2hKEvX5sZStKVLujTuZ84hHzibF1VlbhAB9FhXgsmxJpLod-QU66VXNU1U29fzCfkrJQnxmpuhHpPTqqaq8Zoc0r-fAuwiamMwVFwbsrg9jR5OmAsY56gp22fUkd9yvRxGiDSLWxD36cBdiFPhXY4ohtDijREOsvsgpsfHcRocRkxhrj5SoGWfRlxgGVTxl3A5w_knYe-4MfjeU5-3d78vL5fPfy4-3599bBykslxpXQrtRLG-wZmZ-1BdLxtOEJrPDeeYSuZ7hzjLWjTsopJ3oFXzleNbjxU5-TykLud2gE7h3HM0NttDgPkvU0Q7OubGB7tJu2skaoRdT0HfDkG5PR7wjLaIRSHfQ8R01Ss0LypJZ8tZvTzf-hTmnKcv7dQptZcSzVT_EC5nErJ6P_JcGaXau2xWrtUa5dqq7-5m5s3</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2719671745</pqid></control><display><type>article</type><title>Diagnostic accuracy of menstrual blood for human papillomavirus detection in cervical cancer screening: a systematic review</title><source>Open Access: PubMed Central</source><source>Coronavirus Research Database</source><creator>Chakravarti, Priyal ; Maheshwari, Amita ; Tahlan, Shweta ; Kadam, Prithviraj ; Bagal, Sonali ; Gore, Suvarna ; Panse, Nandkumar ; Deodhar, Kedar ; Chaturvedi, Pankaj ; Dikshit, Rajesh ; Budukh, Atul</creator><creatorcontrib>Chakravarti, Priyal ; Maheshwari, Amita ; Tahlan, Shweta ; Kadam, Prithviraj ; Bagal, Sonali ; Gore, Suvarna ; Panse, Nandkumar ; Deodhar, Kedar ; Chaturvedi, Pankaj ; Dikshit, Rajesh ; Budukh, Atul</creatorcontrib><description>Globally, cervical cancer is the fourth most common cancer among females and a major public health problem in low- and middle-income countries (LMICs). There are several screening tests available for cervical cancer screening; however, due to a lack of organised screening facilities as well as factors such as low participation rates in screening programmes, many women die due to cervical cancer. To reach out to a large number of women, an easy, non-invasive and time-saving screening method is required. Evidence supports that cervical cancer screening with human papillomavirus deoxyribonucleic acid (HPV DNA) testing is the most effective technique for lowering the incidence and mortality associated with cervical cancer when compared to other screening methods. Furthermore, a small number of studies have reported that menstrual blood can be used as an alternative sample for HPV detection for cervical cancer screening. We have done a systematic review of the studies that have reported the diagnostic accuracy of menstrual blood to detect HPV. We found five studies in our literature search. The studies showed the diagnostic accuracy of menstrual blood in terms of sensitivity ranging from 82.8% to 97.7% and specificity ranging from 50.0% to 98.0% in cervical intraepithelial neoplasia or HPV infection detection. This review supports the use of menstrual blood as a screening tool for cervical cancer especially in LMICs where women are reluctant to participate in cervical cancer screening due to issues such as embarrassment and discomfort to test procedures as well as busy schedules. However, further studies are required to compare the diagnostic accuracy of menstrual blood in detecting HPV compared to other self-sampled HPV detection methods. This is one of the methods that can be explored further for use as a cervical cancer screening test.</description><identifier>ISSN: 1754-6605</identifier><identifier>EISSN: 1754-6605</identifier><identifier>DOI: 10.3332/ecancer.2022.1427</identifier><identifier>PMID: 36158979</identifier><language>eng</language><publisher>Bristol: Cancer Intelligence</publisher><subject>Accuracy ; Cellular biology ; Cervical cancer ; Deoxyribonucleic acid ; Disease prevention ; DNA ; Genomes ; Human papillomavirus ; Hygiene ; Laboratories ; Medical screening ; Menstruation ; Pap smear ; Review ; Search strategies ; Systematic review ; Womens health</subject><ispartof>Ecancermedicalscience, 2022-07, Vol.16, p.1427-1427</ispartof><rights>the authors; licensee e cancermedicalscience. 2022. This work is published under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>the authors; licensee cancermedicalscience. 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c404t-57b47529ff8a9797fa2d1b81eab9f19f0eb407dc01ba79b03041daf5cf3878fa3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2719671745/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2719671745?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,315,733,786,790,891,27957,27958,38551,43930,53827,53829,74769</link.rule.ids></links><search><creatorcontrib>Chakravarti, Priyal</creatorcontrib><creatorcontrib>Maheshwari, Amita</creatorcontrib><creatorcontrib>Tahlan, Shweta</creatorcontrib><creatorcontrib>Kadam, Prithviraj</creatorcontrib><creatorcontrib>Bagal, Sonali</creatorcontrib><creatorcontrib>Gore, Suvarna</creatorcontrib><creatorcontrib>Panse, Nandkumar</creatorcontrib><creatorcontrib>Deodhar, Kedar</creatorcontrib><creatorcontrib>Chaturvedi, Pankaj</creatorcontrib><creatorcontrib>Dikshit, Rajesh</creatorcontrib><creatorcontrib>Budukh, Atul</creatorcontrib><title>Diagnostic accuracy of menstrual blood for human papillomavirus detection in cervical cancer screening: a systematic review</title><title>Ecancermedicalscience</title><description>Globally, cervical cancer is the fourth most common cancer among females and a major public health problem in low- and middle-income countries (LMICs). There are several screening tests available for cervical cancer screening; however, due to a lack of organised screening facilities as well as factors such as low participation rates in screening programmes, many women die due to cervical cancer. To reach out to a large number of women, an easy, non-invasive and time-saving screening method is required. Evidence supports that cervical cancer screening with human papillomavirus deoxyribonucleic acid (HPV DNA) testing is the most effective technique for lowering the incidence and mortality associated with cervical cancer when compared to other screening methods. Furthermore, a small number of studies have reported that menstrual blood can be used as an alternative sample for HPV detection for cervical cancer screening. We have done a systematic review of the studies that have reported the diagnostic accuracy of menstrual blood to detect HPV. We found five studies in our literature search. The studies showed the diagnostic accuracy of menstrual blood in terms of sensitivity ranging from 82.8% to 97.7% and specificity ranging from 50.0% to 98.0% in cervical intraepithelial neoplasia or HPV infection detection. This review supports the use of menstrual blood as a screening tool for cervical cancer especially in LMICs where women are reluctant to participate in cervical cancer screening due to issues such as embarrassment and discomfort to test procedures as well as busy schedules. However, further studies are required to compare the diagnostic accuracy of menstrual blood in detecting HPV compared to other self-sampled HPV detection methods. This is one of the methods that can be explored further for use as a cervical cancer screening test.</description><subject>Accuracy</subject><subject>Cellular biology</subject><subject>Cervical cancer</subject><subject>Deoxyribonucleic acid</subject><subject>Disease prevention</subject><subject>DNA</subject><subject>Genomes</subject><subject>Human papillomavirus</subject><subject>Hygiene</subject><subject>Laboratories</subject><subject>Medical screening</subject><subject>Menstruation</subject><subject>Pap smear</subject><subject>Review</subject><subject>Search strategies</subject><subject>Systematic review</subject><subject>Womens health</subject><issn>1754-6605</issn><issn>1754-6605</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>COVID</sourceid><sourceid>PIMPY</sourceid><recordid>eNpdkc1q3DAUhUVpaX7aB-hO0E03M5FkybK6CIQ0P4VAN-1aXMtXEwVbmkr2hKEvX5sZStKVLujTuZ84hHzibF1VlbhAB9FhXgsmxJpLod-QU66VXNU1U29fzCfkrJQnxmpuhHpPTqqaq8Zoc0r-fAuwiamMwVFwbsrg9jR5OmAsY56gp22fUkd9yvRxGiDSLWxD36cBdiFPhXY4ohtDijREOsvsgpsfHcRocRkxhrj5SoGWfRlxgGVTxl3A5w_knYe-4MfjeU5-3d78vL5fPfy4-3599bBykslxpXQrtRLG-wZmZ-1BdLxtOEJrPDeeYSuZ7hzjLWjTsopJ3oFXzleNbjxU5-TykLud2gE7h3HM0NttDgPkvU0Q7OubGB7tJu2skaoRdT0HfDkG5PR7wjLaIRSHfQ8R01Ss0LypJZ8tZvTzf-hTmnKcv7dQptZcSzVT_EC5nErJ6P_JcGaXau2xWrtUa5dqq7-5m5s3</recordid><startdate>20220714</startdate><enddate>20220714</enddate><creator>Chakravarti, Priyal</creator><creator>Maheshwari, Amita</creator><creator>Tahlan, Shweta</creator><creator>Kadam, Prithviraj</creator><creator>Bagal, Sonali</creator><creator>Gore, Suvarna</creator><creator>Panse, Nandkumar</creator><creator>Deodhar, Kedar</creator><creator>Chaturvedi, Pankaj</creator><creator>Dikshit, Rajesh</creator><creator>Budukh, Atul</creator><general>Cancer Intelligence</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>COVID</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20220714</creationdate><title>Diagnostic accuracy of menstrual blood for human papillomavirus detection in cervical cancer screening: a systematic review</title><author>Chakravarti, Priyal ; Maheshwari, Amita ; Tahlan, Shweta ; Kadam, Prithviraj ; Bagal, Sonali ; Gore, Suvarna ; Panse, Nandkumar ; Deodhar, Kedar ; Chaturvedi, Pankaj ; Dikshit, Rajesh ; Budukh, Atul</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c404t-57b47529ff8a9797fa2d1b81eab9f19f0eb407dc01ba79b03041daf5cf3878fa3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Accuracy</topic><topic>Cellular biology</topic><topic>Cervical cancer</topic><topic>Deoxyribonucleic acid</topic><topic>Disease prevention</topic><topic>DNA</topic><topic>Genomes</topic><topic>Human papillomavirus</topic><topic>Hygiene</topic><topic>Laboratories</topic><topic>Medical screening</topic><topic>Menstruation</topic><topic>Pap smear</topic><topic>Review</topic><topic>Search strategies</topic><topic>Systematic review</topic><topic>Womens health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chakravarti, Priyal</creatorcontrib><creatorcontrib>Maheshwari, Amita</creatorcontrib><creatorcontrib>Tahlan, Shweta</creatorcontrib><creatorcontrib>Kadam, Prithviraj</creatorcontrib><creatorcontrib>Bagal, Sonali</creatorcontrib><creatorcontrib>Gore, Suvarna</creatorcontrib><creatorcontrib>Panse, Nandkumar</creatorcontrib><creatorcontrib>Deodhar, Kedar</creatorcontrib><creatorcontrib>Chaturvedi, Pankaj</creatorcontrib><creatorcontrib>Dikshit, Rajesh</creatorcontrib><creatorcontrib>Budukh, Atul</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection (Proquest)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Coronavirus Research Database</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>ProQuest - Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Ecancermedicalscience</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chakravarti, Priyal</au><au>Maheshwari, Amita</au><au>Tahlan, Shweta</au><au>Kadam, Prithviraj</au><au>Bagal, Sonali</au><au>Gore, Suvarna</au><au>Panse, Nandkumar</au><au>Deodhar, Kedar</au><au>Chaturvedi, Pankaj</au><au>Dikshit, Rajesh</au><au>Budukh, Atul</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Diagnostic accuracy of menstrual blood for human papillomavirus detection in cervical cancer screening: a systematic review</atitle><jtitle>Ecancermedicalscience</jtitle><date>2022-07-14</date><risdate>2022</risdate><volume>16</volume><spage>1427</spage><epage>1427</epage><pages>1427-1427</pages><issn>1754-6605</issn><eissn>1754-6605</eissn><notes>ObjectType-Article-2</notes><notes>SourceType-Scholarly Journals-1</notes><notes>ObjectType-Feature-3</notes><notes>content type line 23</notes><notes>ObjectType-Review-1</notes><abstract>Globally, cervical cancer is the fourth most common cancer among females and a major public health problem in low- and middle-income countries (LMICs). There are several screening tests available for cervical cancer screening; however, due to a lack of organised screening facilities as well as factors such as low participation rates in screening programmes, many women die due to cervical cancer. To reach out to a large number of women, an easy, non-invasive and time-saving screening method is required. Evidence supports that cervical cancer screening with human papillomavirus deoxyribonucleic acid (HPV DNA) testing is the most effective technique for lowering the incidence and mortality associated with cervical cancer when compared to other screening methods. Furthermore, a small number of studies have reported that menstrual blood can be used as an alternative sample for HPV detection for cervical cancer screening. We have done a systematic review of the studies that have reported the diagnostic accuracy of menstrual blood to detect HPV. We found five studies in our literature search. The studies showed the diagnostic accuracy of menstrual blood in terms of sensitivity ranging from 82.8% to 97.7% and specificity ranging from 50.0% to 98.0% in cervical intraepithelial neoplasia or HPV infection detection. This review supports the use of menstrual blood as a screening tool for cervical cancer especially in LMICs where women are reluctant to participate in cervical cancer screening due to issues such as embarrassment and discomfort to test procedures as well as busy schedules. However, further studies are required to compare the diagnostic accuracy of menstrual blood in detecting HPV compared to other self-sampled HPV detection methods. This is one of the methods that can be explored further for use as a cervical cancer screening test.</abstract><cop>Bristol</cop><pub>Cancer Intelligence</pub><pmid>36158979</pmid><doi>10.3332/ecancer.2022.1427</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 1754-6605 |
ispartof | Ecancermedicalscience, 2022-07, Vol.16, p.1427-1427 |
issn | 1754-6605 1754-6605 |
language | eng |
recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9458266 |
source | Open Access: PubMed Central; Coronavirus Research Database |
subjects | Accuracy Cellular biology Cervical cancer Deoxyribonucleic acid Disease prevention DNA Genomes Human papillomavirus Hygiene Laboratories Medical screening Menstruation Pap smear Review Search strategies Systematic review Womens health |
title | Diagnostic accuracy of menstrual blood for human papillomavirus detection in cervical cancer screening: a systematic review |
url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-09-22T03%3A18%3A50IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Diagnostic%20accuracy%20of%20menstrual%20blood%20for%20human%20papillomavirus%20detection%20in%20cervical%20cancer%20screening:%20a%20systematic%20review&rft.jtitle=Ecancermedicalscience&rft.au=Chakravarti,%20Priyal&rft.date=2022-07-14&rft.volume=16&rft.spage=1427&rft.epage=1427&rft.pages=1427-1427&rft.issn=1754-6605&rft.eissn=1754-6605&rft_id=info:doi/10.3332/ecancer.2022.1427&rft_dat=%3Cproquest_pubme%3E2719671745%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c404t-57b47529ff8a9797fa2d1b81eab9f19f0eb407dc01ba79b03041daf5cf3878fa3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2719671745&rft_id=info:pmid/36158979&rfr_iscdi=true |