Air Pollution-Induced Autonomic Modulation

Air pollutants pose a serious worldwide health hazard, causing respiratory and cardiovascular morbidity and mortality. Pollutants perturb the autonomic nervous system, whose function is critical to cardiopulmonary homeostasis. Recent studies suggest that pollutants can stimulate defensive sensory ne...

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Bibliographic Details
Published in:Physiology (Bethesda, Md.) Md.), 2020-11, Vol.35 (6), p.363-374
Main Author: Taylor-Clark, Thomas E
Format: Article
Language:English
Subjects:
Air Pollution - adverse effects
Animals
Autonomic Nervous System - pathology
Cardiovascular Diseases - etiology
Cardiovascular Diseases - pathology
Humans
Lung Diseases - etiology
Lung Diseases - pathology
Review
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Summary:Air pollutants pose a serious worldwide health hazard, causing respiratory and cardiovascular morbidity and mortality. Pollutants perturb the autonomic nervous system, whose function is critical to cardiopulmonary homeostasis. Recent studies suggest that pollutants can stimulate defensive sensory nerves within the cardiopulmonary system, thus providing a possible mechanism for pollutant-induced autonomic dysfunction. A better understanding of the mechanisms involved would likely improve the management and treatment of pollution-related disease.
ISSN:1548-9213
1548-9221
DOI:10.1152/physiol.00017.2020