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Detection of the SARS‐CoV‐2 in different biologic specimens from positive patients with COVID‐19, in Northern Italy

Coronavirus disease 2019 (COVID‐19) diagnosis is based on molecular detection of SARS‐CoV‐2 in respiratory samples such as nasal swab (NS). However, the evidence that NS in patients with pneumonia was sometimes negative raises the attention to collect other clinical specimens. SARS‐CoV‐2 was shown i...

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Published in:Pediatric allergy and immunology 2020-11, Vol.31 (S26), p.72-74
Main Authors: Piralla, Antonio, Bruno, Raffaele, Baldanti, Fausto, Brunetti, E, Di Matteo, A, Seminari, E, Zuccaro, V, Pagnucco, L, Mariani, B, Ludovisi, S, Lissandrin, R, Parisi, A, Michelone, G, Zanaboni, D, Novati, S, Orsolini, P, Vecchia, M, Sciarra, M, Colaneri, M, Di Filippo, A, Sambo, M, Lupi, M, Roda, S, Pieri, TC, Sachs, M, Valsecchi, P, Bonzano, M, Briganti, F, Crescenzi, G, Falchi, AG, Guarnone, R, Guglielmana, B, Maggi, E, Martino, I, Speciale, F, Zunino, I, Secco, G, Cappa, G, Chiodi, B, Barcella, B, Resta, F, Moroni, L, Zattera, C, Tassi, MF, Bazzini, M, Belliato, M, Perotti, L, Tavazzi, G, Licari, A, Barbarini, D, Cambieri, P, Cavanna, C, Comolli, G, Daturi, R, Monzillo, E, Parea, M, Percivalle, E, Rovida, F, Adzasehoun, G, Ardizzone, M, Bellotti, L, Capella, L, Devitis, D, Dossena, L, Frisco, G, Girello, A, Landini, V, Maliardi, V, Piemontese, P, Pezzaia, S, Premoli, M, Rebuffa, C, Bagnarino, J, Bergami, F, Bonetti, A, Caneva, G, Corcione, A, Di Martino, R, Ferrari, A, Ferrari, G, Fiorina, L, Gallone, A, Giardina, F, Mercato, A, Ratano, G, Sciabica, IM, Tallarita, M, Vitali, J, Cerino, A, Varchetta, S, Tizzoni, M, Nicora, C, Petronella, V, Marena, C, Muzzi, A, Cutti, S, Batisti Biffignandi, G, Rettani, M, Marseglia, Gian Luigi
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Language:English
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Summary:Coronavirus disease 2019 (COVID‐19) diagnosis is based on molecular detection of SARS‐CoV‐2 in respiratory samples such as nasal swab (NS). However, the evidence that NS in patients with pneumonia was sometimes negative raises the attention to collect other clinical specimens. SARS‐CoV‐2 was shown in 10.3% rectal swabs (RS), 7.7% plasma, 1% urine, and 0% feces from 143 NS‐positive patients. Potential infection by fluids different from respiratory secretion is possible but unlikely.
ISSN:0905-6157
1399-3038
DOI:10.1111/pai.13366