Association Between Cannabis Use and Healthcare Utilization in Patients With Irritable Bowel Syndrome: A Retrospective Cohort Study

IntroductionIrritable bowel syndrome (IBS) is a frequent cause of abdominal pain and altered bowel habits, which is associated with significant healthcare utilization. The effects of the active compound of cannabis, Δ9-tetrahydrocannabinol (THC), on gut motility and tone have been studied in several...

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Published in:Curēus (Palo Alto, CA) CA), 2020-05, Vol.12 (5), p.e8008-e8008
Main Authors: Desai, Parth, Mbachi, Chimezie, Vohra, Ishaan, Salazar, Miguel, Mathew, Madhu, Randhawa, Tejinder, Haque, Zohaib, Wang, Yuchen, Attar, Bashar, Paintsil, Isaac
Format: Article
Language:English
Subjects:
Abdomen
Ambulatory care
Anemia
Clinical outcomes
Cohort analysis
Constipation
Diabetes
Endoscopy
Family income
Gastroenterology
Health care policy
Health services utilization
Heart failure
Hospitals
Hypothyroidism
Inflammatory bowel disease
Internal Medicine
Irritable bowel syndrome
Marijuana
Medicaid
Morbidity
Motility
Pain
Quality of life
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container_issue 5
container_start_page e8008
container_title Curēus (Palo Alto, CA)
container_volume 12
creator Desai, Parth
Mbachi, Chimezie
Vohra, Ishaan
Salazar, Miguel
Mathew, Madhu
Randhawa, Tejinder
Haque, Zohaib
Wang, Yuchen
Attar, Bashar
Paintsil, Isaac
description IntroductionIrritable bowel syndrome (IBS) is a frequent cause of abdominal pain and altered bowel habits, which is associated with significant healthcare utilization. The effects of the active compound of cannabis, Δ9-tetrahydrocannabinol (THC), on gut motility and tone have been studied in several experimental models. It is unknown whether these effects correlate with improved healthcare utilization among cannabis users. The purpose of this study is to evaluate the impact of cannabis use on inpatient length of stay and resource utilization for patients with a primary discharge diagnosis of IBS.MethodsData were extracted from the Healthcare Cost and Utilization Project Nationwide Inpatient Sample database from 2010 to 2014 for all patients with a primary discharge diagnosis of IBS. Cannabis users (n=246) and non-users (n=9147) were directly compared for various clinical outcomes.ResultsCannabis users were less likely to have the following: upper gastrointestinal endoscopy (17.9% vs. 26.1%; adjusted odds ratio [aOR]: 0.51 [0.36 to 0.73]; p
doi_str_mv 10.7759/cureus.8008
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The effects of the active compound of cannabis, Δ9-tetrahydrocannabinol (THC), on gut motility and tone have been studied in several experimental models. It is unknown whether these effects correlate with improved healthcare utilization among cannabis users. The purpose of this study is to evaluate the impact of cannabis use on inpatient length of stay and resource utilization for patients with a primary discharge diagnosis of IBS.MethodsData were extracted from the Healthcare Cost and Utilization Project Nationwide Inpatient Sample database from 2010 to 2014 for all patients with a primary discharge diagnosis of IBS. Cannabis users (n=246) and non-users (n=9147) were directly compared for various clinical outcomes.ResultsCannabis users were less likely to have the following: upper gastrointestinal endoscopy (17.9% vs. 26.1%; adjusted odds ratio [aOR]: 0.51 [0.36 to 0.73]; p&lt;0.001) and lower gastrointestinal endoscopy (21.1% vs. 28.7%; aOR: 0.54 [0.39 to 0.75]; p&lt;0.001). Additionally, cannabis users had shorter length of stay (2.8 days vs. 3.6 days; p=0.004) and less total charges (US$20,388 vs. US$23,624). There was no difference in the frequency of CT abdomen performed.ConclusionsCannabis use may decrease inpatient healthcare utilization in IBS patients. These effects could possibly be through the effect of cannabis on the endocannabinoid system.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.8008</identifier><identifier>PMID: 32528750</identifier><language>eng</language><publisher>Palo Alto: Cureus Inc</publisher><subject>Abdomen ; Ambulatory care ; Anemia ; Clinical outcomes ; Cohort analysis ; Constipation ; Diabetes ; Endoscopy ; Family income ; Gastroenterology ; Health care policy ; Health services utilization ; Heart failure ; Hospitals ; Hypothyroidism ; Inflammatory bowel disease ; Internal Medicine ; Irritable bowel syndrome ; Marijuana ; Medicaid ; Morbidity ; Motility ; Pain ; Quality of life</subject><ispartof>Curēus (Palo Alto, CA), 2020-05, Vol.12 (5), p.e8008-e8008</ispartof><rights>Copyright © 2020, Desai et al. This work is published under http://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2020, Desai et al. 2020 Desai et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c316t-fb8eca3f165884facc3e578251fec98931fe14b61ff7a11600e8070e9f5432033</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279677/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279677/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,733,786,790,891,27957,27958,53827,53829</link.rule.ids></links><search><creatorcontrib>Desai, Parth</creatorcontrib><creatorcontrib>Mbachi, Chimezie</creatorcontrib><creatorcontrib>Vohra, Ishaan</creatorcontrib><creatorcontrib>Salazar, Miguel</creatorcontrib><creatorcontrib>Mathew, Madhu</creatorcontrib><creatorcontrib>Randhawa, Tejinder</creatorcontrib><creatorcontrib>Haque, Zohaib</creatorcontrib><creatorcontrib>Wang, Yuchen</creatorcontrib><creatorcontrib>Attar, Bashar</creatorcontrib><creatorcontrib>Paintsil, Isaac</creatorcontrib><title>Association Between Cannabis Use and Healthcare Utilization in Patients With Irritable Bowel Syndrome: A Retrospective Cohort Study</title><title>Curēus (Palo Alto, CA)</title><description>IntroductionIrritable bowel syndrome (IBS) is a frequent cause of abdominal pain and altered bowel habits, which is associated with significant healthcare utilization. The effects of the active compound of cannabis, Δ9-tetrahydrocannabinol (THC), on gut motility and tone have been studied in several experimental models. It is unknown whether these effects correlate with improved healthcare utilization among cannabis users. The purpose of this study is to evaluate the impact of cannabis use on inpatient length of stay and resource utilization for patients with a primary discharge diagnosis of IBS.MethodsData were extracted from the Healthcare Cost and Utilization Project Nationwide Inpatient Sample database from 2010 to 2014 for all patients with a primary discharge diagnosis of IBS. Cannabis users (n=246) and non-users (n=9147) were directly compared for various clinical outcomes.ResultsCannabis users were less likely to have the following: upper gastrointestinal endoscopy (17.9% vs. 26.1%; adjusted odds ratio [aOR]: 0.51 [0.36 to 0.73]; p&lt;0.001) and lower gastrointestinal endoscopy (21.1% vs. 28.7%; aOR: 0.54 [0.39 to 0.75]; p&lt;0.001). Additionally, cannabis users had shorter length of stay (2.8 days vs. 3.6 days; p=0.004) and less total charges (US$20,388 vs. US$23,624). There was no difference in the frequency of CT abdomen performed.ConclusionsCannabis use may decrease inpatient healthcare utilization in IBS patients. 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The effects of the active compound of cannabis, Δ9-tetrahydrocannabinol (THC), on gut motility and tone have been studied in several experimental models. It is unknown whether these effects correlate with improved healthcare utilization among cannabis users. The purpose of this study is to evaluate the impact of cannabis use on inpatient length of stay and resource utilization for patients with a primary discharge diagnosis of IBS.MethodsData were extracted from the Healthcare Cost and Utilization Project Nationwide Inpatient Sample database from 2010 to 2014 for all patients with a primary discharge diagnosis of IBS. Cannabis users (n=246) and non-users (n=9147) were directly compared for various clinical outcomes.ResultsCannabis users were less likely to have the following: upper gastrointestinal endoscopy (17.9% vs. 26.1%; adjusted odds ratio [aOR]: 0.51 [0.36 to 0.73]; p&lt;0.001) and lower gastrointestinal endoscopy (21.1% vs. 28.7%; aOR: 0.54 [0.39 to 0.75]; p&lt;0.001). Additionally, cannabis users had shorter length of stay (2.8 days vs. 3.6 days; p=0.004) and less total charges (US$20,388 vs. US$23,624). There was no difference in the frequency of CT abdomen performed.ConclusionsCannabis use may decrease inpatient healthcare utilization in IBS patients. These effects could possibly be through the effect of cannabis on the endocannabinoid system.</abstract><cop>Palo Alto</cop><pub>Cureus Inc</pub><pmid>32528750</pmid><doi>10.7759/cureus.8008</doi><oa>free_for_read</oa></addata></record>
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subjects Abdomen
Ambulatory care
Anemia
Clinical outcomes
Cohort analysis
Constipation
Diabetes
Endoscopy
Family income
Gastroenterology
Health care policy
Health services utilization
Heart failure
Hospitals
Hypothyroidism
Inflammatory bowel disease
Internal Medicine
Irritable bowel syndrome
Marijuana
Medicaid
Morbidity
Motility
Pain
Quality of life
title Association Between Cannabis Use and Healthcare Utilization in Patients With Irritable Bowel Syndrome: A Retrospective Cohort Study
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