Effect of elective percutaneous coronary intervention of left anterior descending coronary artery on regional myocardial function using strain imaging

Percutaneous coronary intervention (PCI) is a commonly used procedure for revascularization, however the impairment of regional myocardial function in patients with stable coronary artery disease (CAD) has not been well characterized, our study aimed to assess the improvement of left ventricular (LV...

Full description

Saved in:
Bibliographic Details
Published in:The Egyptian heart journal 2018-06, Vol.70 (2), p.83-88
Main Authors: Magdy, Gehan, Sadaka, Mohammed, Elzawawy, Tarek, Elmaghraby, Abdallah
Format: Article
Language:English
Subjects:
Percutaneous cardiac intervention
Percutaneous coronary intervention
Regional myocardial function
Strain imaging
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c451t-a9ff4386942664b49e201ed861ab2b2efb86736bd42fd1a2f45c18906ec3dcef3
cites cdi_FETCH-LOGICAL-c451t-a9ff4386942664b49e201ed861ab2b2efb86736bd42fd1a2f45c18906ec3dcef3
container_end_page 88
container_issue 2
container_start_page 83
container_title The Egyptian heart journal
container_volume 70
creator Magdy, Gehan
Sadaka, Mohammed
Elzawawy, Tarek
Elmaghraby, Abdallah
description Percutaneous coronary intervention (PCI) is a commonly used procedure for revascularization, however the impairment of regional myocardial function in patients with stable coronary artery disease (CAD) has not been well characterized, our study aimed to assess the improvement of left ventricular (LV) systolic function after elective PCI of the left anterior descending artery (LAD) using strain and strain rate imaging techniques. The study included 30 patients (aged 56.8 ± 6.6 years, 66.7% males) presented with stable CAD on optimal medical therapy, and recommended for elective PCI to LAD, all patients included in the study had a normal LV wall motions, and normal LV systolic function. Tissue Doppler imaging (TDI) was done before PCI, immediately, and three months post PCI. The peak systolic longitudinal strain (PSLS), and peak systolic strain rate (PSSR) were measured and averaged for the 6 LAD segments (the basal, mid, and apical segments of the anterior wall, the basal, mid anteroseptal, and the apicoseptal segments), 15 healthy control subjects were included as a control group. The average PSLS and PSSR of the ischemic segments were significantly lower in patients compared to control in the ischemic segments, and significantly increased 3 months post PCI but not immediately post PCI. Using the ROC curve a cutoff value of −13.69% for PSLS can detect regional ischemia with a sensitivity 93.3% and a specificity of 80%. TDI derived strain and strain rate can detect resting regional myocardial dysfunction in presence of preserved LV systolic function, and can assess the improvement of regional myocardial function after successful elective PCI in patients with stable CAD.
doi_str_mv 10.1016/j.ehj.2017.12.003
format article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6112371</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S111026081730128X</els_id><sourcerecordid>2098762192</sourcerecordid><originalsourceid>FETCH-LOGICAL-c451t-a9ff4386942664b49e201ed861ab2b2efb86736bd42fd1a2f45c18906ec3dcef3</originalsourceid><addsrcrecordid>eNp9UcFq3DAQFaWhWZJ8QC9Fx17saGRHtikUSkjbQKCXBnoTsjzaaPFKW8le2B_J93acTdP2Ul00mnnvaXiPsbcgShCgLjclPmxKKaApQZZCVK_YSopOFB3Aj9dsBQCikEq0p-wi542go2RTifoNO61IQLVts2KPN86hnXh0HEcq_B75DpOdJxMwzpnbmGIw6cB9mDDtMUw-hgU-opu4WZo-Jj5gthgGH9Z_GCbR8MAJnnBNLDPy7SFakwZPpZuDfdKa88LKUzI-cL81a3qesxNnxowXz_cZu_988_36a3H37cvt9ae7wtZXMBWmc66uWtXVUqm6rzskP3BoFZhe9hJd36qmUv1QSzeAka6-stB2QqGtBouuOmMfj7q7ud8itQKtMepdoj3SQUfj9b-T4B_0Ou61ApBVAyTw_lkgxZ8z5klvPTkxjkf7NCXSNkpCJwkKR6hNMeeE7uUbEHqJVG80RaqXSDVITZES593f-70wfgdIgA9HAJJLe49JZ-sxWBx8ojj1EP1_5H8Bj7W3oQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2098762192</pqid></control><display><type>article</type><title>Effect of elective percutaneous coronary intervention of left anterior descending coronary artery on regional myocardial function using strain imaging</title><source>ScienceDirect</source><source>PubMed Central</source><creator>Magdy, Gehan ; Sadaka, Mohammed ; Elzawawy, Tarek ; Elmaghraby, Abdallah</creator><creatorcontrib>Magdy, Gehan ; Sadaka, Mohammed ; Elzawawy, Tarek ; Elmaghraby, Abdallah</creatorcontrib><description>Percutaneous coronary intervention (PCI) is a commonly used procedure for revascularization, however the impairment of regional myocardial function in patients with stable coronary artery disease (CAD) has not been well characterized, our study aimed to assess the improvement of left ventricular (LV) systolic function after elective PCI of the left anterior descending artery (LAD) using strain and strain rate imaging techniques. The study included 30 patients (aged 56.8 ± 6.6 years, 66.7% males) presented with stable CAD on optimal medical therapy, and recommended for elective PCI to LAD, all patients included in the study had a normal LV wall motions, and normal LV systolic function. Tissue Doppler imaging (TDI) was done before PCI, immediately, and three months post PCI. The peak systolic longitudinal strain (PSLS), and peak systolic strain rate (PSSR) were measured and averaged for the 6 LAD segments (the basal, mid, and apical segments of the anterior wall, the basal, mid anteroseptal, and the apicoseptal segments), 15 healthy control subjects were included as a control group. The average PSLS and PSSR of the ischemic segments were significantly lower in patients compared to control in the ischemic segments, and significantly increased 3 months post PCI but not immediately post PCI. Using the ROC curve a cutoff value of −13.69% for PSLS can detect regional ischemia with a sensitivity 93.3% and a specificity of 80%. TDI derived strain and strain rate can detect resting regional myocardial dysfunction in presence of preserved LV systolic function, and can assess the improvement of regional myocardial function after successful elective PCI in patients with stable CAD.</description><identifier>ISSN: 1110-2608</identifier><identifier>EISSN: 2090-911X</identifier><identifier>DOI: 10.1016/j.ehj.2017.12.003</identifier><identifier>PMID: 30166887</identifier><language>eng</language><publisher>Germany: Elsevier B.V</publisher><subject>Percutaneous cardiac intervention ; Percutaneous coronary intervention ; Regional myocardial function ; Strain imaging</subject><ispartof>The Egyptian heart journal, 2018-06, Vol.70 (2), p.83-88</ispartof><rights>2017 Egyptian Society of Cardiology</rights><rights>2017 Egyptian Society of Cardiology. Production and hosting by Elsevier B.V. 2017 Egyptian Society of Cardiology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c451t-a9ff4386942664b49e201ed861ab2b2efb86736bd42fd1a2f45c18906ec3dcef3</citedby><cites>FETCH-LOGICAL-c451t-a9ff4386942664b49e201ed861ab2b2efb86736bd42fd1a2f45c18906ec3dcef3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112371/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S111026081730128X$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>230,315,730,783,787,888,3556,27936,27937,45792,53804,53806</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30166887$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Magdy, Gehan</creatorcontrib><creatorcontrib>Sadaka, Mohammed</creatorcontrib><creatorcontrib>Elzawawy, Tarek</creatorcontrib><creatorcontrib>Elmaghraby, Abdallah</creatorcontrib><title>Effect of elective percutaneous coronary intervention of left anterior descending coronary artery on regional myocardial function using strain imaging</title><title>The Egyptian heart journal</title><addtitle>Egypt Heart J</addtitle><description>Percutaneous coronary intervention (PCI) is a commonly used procedure for revascularization, however the impairment of regional myocardial function in patients with stable coronary artery disease (CAD) has not been well characterized, our study aimed to assess the improvement of left ventricular (LV) systolic function after elective PCI of the left anterior descending artery (LAD) using strain and strain rate imaging techniques. The study included 30 patients (aged 56.8 ± 6.6 years, 66.7% males) presented with stable CAD on optimal medical therapy, and recommended for elective PCI to LAD, all patients included in the study had a normal LV wall motions, and normal LV systolic function. Tissue Doppler imaging (TDI) was done before PCI, immediately, and three months post PCI. The peak systolic longitudinal strain (PSLS), and peak systolic strain rate (PSSR) were measured and averaged for the 6 LAD segments (the basal, mid, and apical segments of the anterior wall, the basal, mid anteroseptal, and the apicoseptal segments), 15 healthy control subjects were included as a control group. The average PSLS and PSSR of the ischemic segments were significantly lower in patients compared to control in the ischemic segments, and significantly increased 3 months post PCI but not immediately post PCI. Using the ROC curve a cutoff value of −13.69% for PSLS can detect regional ischemia with a sensitivity 93.3% and a specificity of 80%. TDI derived strain and strain rate can detect resting regional myocardial dysfunction in presence of preserved LV systolic function, and can assess the improvement of regional myocardial function after successful elective PCI in patients with stable CAD.</description><subject>Percutaneous cardiac intervention</subject><subject>Percutaneous coronary intervention</subject><subject>Regional myocardial function</subject><subject>Strain imaging</subject><issn>1110-2608</issn><issn>2090-911X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNp9UcFq3DAQFaWhWZJ8QC9Fx17saGRHtikUSkjbQKCXBnoTsjzaaPFKW8le2B_J93acTdP2Ul00mnnvaXiPsbcgShCgLjclPmxKKaApQZZCVK_YSopOFB3Aj9dsBQCikEq0p-wi542go2RTifoNO61IQLVts2KPN86hnXh0HEcq_B75DpOdJxMwzpnbmGIw6cB9mDDtMUw-hgU-opu4WZo-Jj5gthgGH9Z_GCbR8MAJnnBNLDPy7SFakwZPpZuDfdKa88LKUzI-cL81a3qesxNnxowXz_cZu_988_36a3H37cvt9ae7wtZXMBWmc66uWtXVUqm6rzskP3BoFZhe9hJd36qmUv1QSzeAka6-stB2QqGtBouuOmMfj7q7ud8itQKtMepdoj3SQUfj9b-T4B_0Ou61ApBVAyTw_lkgxZ8z5klvPTkxjkf7NCXSNkpCJwkKR6hNMeeE7uUbEHqJVG80RaqXSDVITZES593f-70wfgdIgA9HAJJLe49JZ-sxWBx8ojj1EP1_5H8Bj7W3oQ</recordid><startdate>20180601</startdate><enddate>20180601</enddate><creator>Magdy, Gehan</creator><creator>Sadaka, Mohammed</creator><creator>Elzawawy, Tarek</creator><creator>Elmaghraby, Abdallah</creator><general>Elsevier B.V</general><general>Egyptian Society of Cardiology</general><scope>6I.</scope><scope>AAFTH</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20180601</creationdate><title>Effect of elective percutaneous coronary intervention of left anterior descending coronary artery on regional myocardial function using strain imaging</title><author>Magdy, Gehan ; Sadaka, Mohammed ; Elzawawy, Tarek ; Elmaghraby, Abdallah</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c451t-a9ff4386942664b49e201ed861ab2b2efb86736bd42fd1a2f45c18906ec3dcef3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Percutaneous cardiac intervention</topic><topic>Percutaneous coronary intervention</topic><topic>Regional myocardial function</topic><topic>Strain imaging</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Magdy, Gehan</creatorcontrib><creatorcontrib>Sadaka, Mohammed</creatorcontrib><creatorcontrib>Elzawawy, Tarek</creatorcontrib><creatorcontrib>Elmaghraby, Abdallah</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>The Egyptian heart journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Magdy, Gehan</au><au>Sadaka, Mohammed</au><au>Elzawawy, Tarek</au><au>Elmaghraby, Abdallah</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of elective percutaneous coronary intervention of left anterior descending coronary artery on regional myocardial function using strain imaging</atitle><jtitle>The Egyptian heart journal</jtitle><addtitle>Egypt Heart J</addtitle><date>2018-06-01</date><risdate>2018</risdate><volume>70</volume><issue>2</issue><spage>83</spage><epage>88</epage><pages>83-88</pages><issn>1110-2608</issn><eissn>2090-911X</eissn><abstract>Percutaneous coronary intervention (PCI) is a commonly used procedure for revascularization, however the impairment of regional myocardial function in patients with stable coronary artery disease (CAD) has not been well characterized, our study aimed to assess the improvement of left ventricular (LV) systolic function after elective PCI of the left anterior descending artery (LAD) using strain and strain rate imaging techniques. The study included 30 patients (aged 56.8 ± 6.6 years, 66.7% males) presented with stable CAD on optimal medical therapy, and recommended for elective PCI to LAD, all patients included in the study had a normal LV wall motions, and normal LV systolic function. Tissue Doppler imaging (TDI) was done before PCI, immediately, and three months post PCI. The peak systolic longitudinal strain (PSLS), and peak systolic strain rate (PSSR) were measured and averaged for the 6 LAD segments (the basal, mid, and apical segments of the anterior wall, the basal, mid anteroseptal, and the apicoseptal segments), 15 healthy control subjects were included as a control group. The average PSLS and PSSR of the ischemic segments were significantly lower in patients compared to control in the ischemic segments, and significantly increased 3 months post PCI but not immediately post PCI. Using the ROC curve a cutoff value of −13.69% for PSLS can detect regional ischemia with a sensitivity 93.3% and a specificity of 80%. TDI derived strain and strain rate can detect resting regional myocardial dysfunction in presence of preserved LV systolic function, and can assess the improvement of regional myocardial function after successful elective PCI in patients with stable CAD.</abstract><cop>Germany</cop><pub>Elsevier B.V</pub><pmid>30166887</pmid><doi>10.1016/j.ehj.2017.12.003</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1110-2608
ispartof The Egyptian heart journal, 2018-06, Vol.70 (2), p.83-88
issn 1110-2608
2090-911X
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6112371
source ScienceDirect; PubMed Central
subjects Percutaneous cardiac intervention
Percutaneous coronary intervention
Regional myocardial function
Strain imaging
title Effect of elective percutaneous coronary intervention of left anterior descending coronary artery on regional myocardial function using strain imaging
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-11-15T19%3A19%3A33IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effect%20of%20elective%20percutaneous%20coronary%20intervention%20of%20left%20anterior%20descending%20coronary%20artery%20on%20regional%20myocardial%20function%20using%20strain%20imaging&rft.jtitle=The%20Egyptian%20heart%20journal&rft.au=Magdy,%20Gehan&rft.date=2018-06-01&rft.volume=70&rft.issue=2&rft.spage=83&rft.epage=88&rft.pages=83-88&rft.issn=1110-2608&rft.eissn=2090-911X&rft_id=info:doi/10.1016/j.ehj.2017.12.003&rft_dat=%3Cproquest_pubme%3E2098762192%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c451t-a9ff4386942664b49e201ed861ab2b2efb86736bd42fd1a2f45c18906ec3dcef3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2098762192&rft_id=info:pmid/30166887&rfr_iscdi=true