Value of automatic patient motion detection and correction in myocardial perfusion imaging using a CZT-based SPECT camera

Correction of motion has become feasible on cadmium-zinc-telluride (CZT)-based SPECT cameras during myocardial perfusion imaging (MPI). Our aim was to quantify the motion and to determine the value of automatic correction using commercially available software. We retrospectively included 83 consecut...

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Bibliographic Details
Published in:Journal of nuclear cardiology 2018-04, Vol.25 (2), p.419-428
Main Authors: van Dijk, Joris D., van Dalen, Jorn A., Mouden, Mohamed, Ottervanger, Jan Paul, Knollema, Siert, Slump, Cornelis H., Jager, Pieter L.
Format: Article
Language:English
Subjects:
Aged
Cadmium
cadmium-zinc-telluride (CZT)
Cardiology
Female
Humans
Image Processing, Computer-Assisted - methods
Imaging
Male
Medicine
Medicine & Public Health
Middle Aged
Motion
motion correction
Myocardial Perfusion Imaging
Myocardial perfusion imaging (MPI)
Nuclear Medicine
Original
Original Article
patient motion
Patients
Pattern Recognition, Automated
Radiology
Reference Standards
Reproducibility of Results
Respiration
respiratory motion
Retrospective Studies
Software
Tellurium
Tomography, Emission-Computed, Single-Photon - instrumentation
Zinc
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Summary:Correction of motion has become feasible on cadmium-zinc-telluride (CZT)-based SPECT cameras during myocardial perfusion imaging (MPI). Our aim was to quantify the motion and to determine the value of automatic correction using commercially available software. We retrospectively included 83 consecutive patients who underwent stress-rest MPI CZT-SPECT and invasive fractional flow reserve (FFR) measurement. Eight-minute stress acquisitions were reformatted into 1.0- and 20-second bins to detect respiratory motion (RM) and patient motion (PM), respectively. RM and PM were quantified and scans were automatically corrected. Total perfusion deficit (TPD) and SPECT interpretation—normal, equivocal, or abnormal—were compared between the noncorrected and corrected scans. Scans with a changed SPECT interpretation were compared with FFR, the reference standard. Average RM was 2.5 ± 0.4 mm and maximal PM was 4.5 ± 1.3 mm. RM correction influenced the diagnostic outcomes in two patients based on TPD changes ≥7% and in nine patients based on changed visual interpretation. In only four of these patients, the changed SPECT interpretation corresponded with FFR measurements. Correction for PM did not influence the diagnostic outcomes. Respiratory motion and patient motion were small. Motion correction did not appear to improve the diagnostic outcome and, hence, the added value seems limited in MPI using CZT-based SPECT cameras.
ISSN:1071-3581
1532-6551
DOI:10.1007/s12350-016-0571-7