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Dengue Infection in a Human Immunodeficiency Virus-1 Positive Patient Chronically Infected with Hepatitis B Virus in Western Mexico

Human immunodeficiency virus (HIV) and dengue coinfection has not been extensively studied. We report herein a case of dengue serotype 1 infection in an HIV-1-positive patient coinfected with hepatitis B virus (HBV) in Colima State, Mexico. CD4 cells and HIV-1 viremia remained at normal levels, and...

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Published in:The American journal of tropical medicine and hygiene 2017-01, Vol.96 (1), p.122-125
Main Authors: Delgado-Enciso, Iván, Espinoza-Gómez, Francisco, Ochoa-Jiménez, Rodolfo, Valle-Reyes, Salvador, Vásquez, Clemente, López-Lemus, Uriel A
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container_title The American journal of tropical medicine and hygiene
container_volume 96
creator Delgado-Enciso, Iván
Espinoza-Gómez, Francisco
Ochoa-Jiménez, Rodolfo
Valle-Reyes, Salvador
Vásquez, Clemente
López-Lemus, Uriel A
description Human immunodeficiency virus (HIV) and dengue coinfection has not been extensively studied. We report herein a case of dengue serotype 1 infection in an HIV-1-positive patient coinfected with hepatitis B virus (HBV) in Colima State, Mexico. CD4 cells and HIV-1 viremia remained at normal levels, and no severe complications were observed during this multiple viral infection. The alanine transaminase and aspartate transaminase values were elevated before and during dengue infection. Surprisingly, these parameters were significantly reduced 2 months later. Because of the lack of evidence regarding this multiple viral interaction, further research is required to understand the biologic and clinical course of dengue infection in HIV-1/HBV coinfected patients, especially in tropical regions where dengue virus transmission is highly active.
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subjects Anti-HIV Agents - therapeutic use
Antiretroviral Therapy, Highly Active
CD4 Lymphocyte Count
Dengue - complications
Female
Flaviviridae
Hepatitis B virus
Hepatitis B, Chronic - complications
HIV Infections - complications
HIV Infections - virology
HIV-1
Humans
Lentivirus
Mexico - epidemiology
Middle Aged
Retroviridae
Viremia
title Dengue Infection in a Human Immunodeficiency Virus-1 Positive Patient Chronically Infected with Hepatitis B Virus in Western Mexico
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