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Rostrocaudal gradient of electrical activation in the parasternal intercostal muscles of the dog
1. Because the inspiratory mechanical advantage of the canine parasternal intercostal muscles is greatest in the third interspace and decreases gradually in the caudal direction, the electromyograms of these muscles in interspaces 3, 5 and 7 have been recorded in anaesthetized, spontaneously breathi...
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| Published in: | The Journal of physiology 1996-08, Vol.495 (Pt 1), p.247-254 |
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| container_end_page | 254 |
| container_issue | Pt 1 |
| container_start_page | 247 |
| container_title | The Journal of physiology |
| container_volume | 495 |
| creator | Legrand, A Brancatisano, A Decramer, M De Troyer, A |
| description | 1. Because the inspiratory mechanical advantage of the canine parasternal intercostal muscles is greatest in the third interspace
and decreases gradually in the caudal direction, the electromyograms of these muscles in interspaces 3, 5 and 7 have been
recorded in anaesthetized, spontaneously breathing dogs. Each activity was expressed as a percentage of the activity measured
during tetanic, supramaximal stimulation of the internal intercostal nerve (maximal activity). 2. Parasternal inspiratory
activity during resting, room air breathing was invariably greater in the third than in the fifth interspace (62.0 +/- 6.0
vs. 41.3 +/- 4.6% of maximal activity; P < 0.001) and smallest in the seventh interspace (22.8 +/- 2.7% of maximal activity;
P < 0.001). This distribution of activity persisted during hyperoxic hypercapnia and during breathing against increased inspiratory
airflow resistance. 3. This rostrocaudal distribution of activity also persisted after complete paralysis of the diaphragm
as well as after deafferentation of the ribcage. 4. Studies of the distribution of the muscle fibre types indicated that the
parasternal intercostals in all interspaces had a higher proportion of slow-twitch oxidative (SO; type I) fibres than fast-twitch
oxidative-glycolytic (FOG; type II a) fibres. 5. Thus the topographic distribution of parasternal inspiratory activity along
the rostrocaudal axis of the ribcage is precisely matched with the topographic distribution of mechanical advantage. This
extraordinarily effective pattern of activation probably results from the unequal distribution of central inputs throughout
the parasternal motoneurone pool. |
| doi_str_mv | 10.1113/jphysiol.1996.sp021589 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1160740</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>78439088</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5697-abeceb88e0ae5aeaea2e2f29202fd84eba07a6fc3f1d4463801077022630a28f3</originalsourceid><addsrcrecordid>eNqNkUtv1DAUhS0EKkPhJ4CyYoGUwY_Ejw0SVDxViQqVtfE4NxNXnjjYTqv59zjKtIId8sJX95z72VcHoVcEbwkh7O3NNByTC35LlOLbNGFKWqkeoQ1puKqFUOwx2mBMac1ES56iZyndYEwYVuoMnUnJOeNig379CCnHYM3cGV_to-kcjLkKfQUebI7Olrax2d2a7MJYubHKA1STiSZliGNR3VgKWzClPszJekjL_GLrwv45etIbn-DF6T5HPz99vL74Ul9-__z14v1lbVuuRG12YGEnJWADrYFyKNCeKopp38kGdgYLw3vLetI1DWcSEyxEWY8zbKjs2Tl6t3KneXeAzpYtovF6iu5g4lEH4_S_yugGvQ-3mhCORYML4PUJEMPvGVLWB5cseG9GCHPSQjZMYSmLka9GG0NKEfqHRwjWSzb6Phu9ZKPvsymDL__-4sPYKYyif1j1O-fh-J9Uff3tamk0qiW0WSBvVsjg9sOdi6DXsRSsg3zUxaevsiZ6Mf8BSva1rA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>78439088</pqid></control><display><type>article</type><title>Rostrocaudal gradient of electrical activation in the parasternal intercostal muscles of the dog</title><source>PubMed Central</source><creator>Legrand, A ; Brancatisano, A ; Decramer, M ; De Troyer, A</creator><creatorcontrib>Legrand, A ; Brancatisano, A ; Decramer, M ; De Troyer, A</creatorcontrib><description>1. Because the inspiratory mechanical advantage of the canine parasternal intercostal muscles is greatest in the third interspace
and decreases gradually in the caudal direction, the electromyograms of these muscles in interspaces 3, 5 and 7 have been
recorded in anaesthetized, spontaneously breathing dogs. Each activity was expressed as a percentage of the activity measured
during tetanic, supramaximal stimulation of the internal intercostal nerve (maximal activity). 2. Parasternal inspiratory
activity during resting, room air breathing was invariably greater in the third than in the fifth interspace (62.0 +/- 6.0
vs. 41.3 +/- 4.6% of maximal activity; P < 0.001) and smallest in the seventh interspace (22.8 +/- 2.7% of maximal activity;
P < 0.001). This distribution of activity persisted during hyperoxic hypercapnia and during breathing against increased inspiratory
airflow resistance. 3. This rostrocaudal distribution of activity also persisted after complete paralysis of the diaphragm
as well as after deafferentation of the ribcage. 4. Studies of the distribution of the muscle fibre types indicated that the
parasternal intercostals in all interspaces had a higher proportion of slow-twitch oxidative (SO; type I) fibres than fast-twitch
oxidative-glycolytic (FOG; type II a) fibres. 5. Thus the topographic distribution of parasternal inspiratory activity along
the rostrocaudal axis of the ribcage is precisely matched with the topographic distribution of mechanical advantage. This
extraordinarily effective pattern of activation probably results from the unequal distribution of central inputs throughout
the parasternal motoneurone pool.</description><identifier>ISSN: 0022-3751</identifier><identifier>EISSN: 1469-7793</identifier><identifier>DOI: 10.1113/jphysiol.1996.sp021589</identifier><identifier>PMID: 8866367</identifier><language>eng</language><publisher>England: The Physiological Society</publisher><subject>Animals ; Dogs ; Electromyography ; Intercostal Muscles - physiology ; Respiration - physiology ; Rhizotomy</subject><ispartof>The Journal of physiology, 1996-08, Vol.495 (Pt 1), p.247-254</ispartof><rights>1996 The Physiological Society</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5697-abeceb88e0ae5aeaea2e2f29202fd84eba07a6fc3f1d4463801077022630a28f3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1160740/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1160740/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,315,733,786,790,891,27957,27958,53827,53829</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8866367$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Legrand, A</creatorcontrib><creatorcontrib>Brancatisano, A</creatorcontrib><creatorcontrib>Decramer, M</creatorcontrib><creatorcontrib>De Troyer, A</creatorcontrib><title>Rostrocaudal gradient of electrical activation in the parasternal intercostal muscles of the dog</title><title>The Journal of physiology</title><addtitle>J Physiol</addtitle><description>1. Because the inspiratory mechanical advantage of the canine parasternal intercostal muscles is greatest in the third interspace
and decreases gradually in the caudal direction, the electromyograms of these muscles in interspaces 3, 5 and 7 have been
recorded in anaesthetized, spontaneously breathing dogs. Each activity was expressed as a percentage of the activity measured
during tetanic, supramaximal stimulation of the internal intercostal nerve (maximal activity). 2. Parasternal inspiratory
activity during resting, room air breathing was invariably greater in the third than in the fifth interspace (62.0 +/- 6.0
vs. 41.3 +/- 4.6% of maximal activity; P < 0.001) and smallest in the seventh interspace (22.8 +/- 2.7% of maximal activity;
P < 0.001). This distribution of activity persisted during hyperoxic hypercapnia and during breathing against increased inspiratory
airflow resistance. 3. This rostrocaudal distribution of activity also persisted after complete paralysis of the diaphragm
as well as after deafferentation of the ribcage. 4. Studies of the distribution of the muscle fibre types indicated that the
parasternal intercostals in all interspaces had a higher proportion of slow-twitch oxidative (SO; type I) fibres than fast-twitch
oxidative-glycolytic (FOG; type II a) fibres. 5. Thus the topographic distribution of parasternal inspiratory activity along
the rostrocaudal axis of the ribcage is precisely matched with the topographic distribution of mechanical advantage. This
extraordinarily effective pattern of activation probably results from the unequal distribution of central inputs throughout
the parasternal motoneurone pool.</description><subject>Animals</subject><subject>Dogs</subject><subject>Electromyography</subject><subject>Intercostal Muscles - physiology</subject><subject>Respiration - physiology</subject><subject>Rhizotomy</subject><issn>0022-3751</issn><issn>1469-7793</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1996</creationdate><recordtype>article</recordtype><recordid>eNqNkUtv1DAUhS0EKkPhJ4CyYoGUwY_Ejw0SVDxViQqVtfE4NxNXnjjYTqv59zjKtIId8sJX95z72VcHoVcEbwkh7O3NNByTC35LlOLbNGFKWqkeoQ1puKqFUOwx2mBMac1ES56iZyndYEwYVuoMnUnJOeNig379CCnHYM3cGV_to-kcjLkKfQUebI7Olrax2d2a7MJYubHKA1STiSZliGNR3VgKWzClPszJekjL_GLrwv45etIbn-DF6T5HPz99vL74Ul9-__z14v1lbVuuRG12YGEnJWADrYFyKNCeKopp38kGdgYLw3vLetI1DWcSEyxEWY8zbKjs2Tl6t3KneXeAzpYtovF6iu5g4lEH4_S_yugGvQ-3mhCORYML4PUJEMPvGVLWB5cseG9GCHPSQjZMYSmLka9GG0NKEfqHRwjWSzb6Phu9ZKPvsymDL__-4sPYKYyif1j1O-fh-J9Uff3tamk0qiW0WSBvVsjg9sOdi6DXsRSsg3zUxaevsiZ6Mf8BSva1rA</recordid><startdate>19960815</startdate><enddate>19960815</enddate><creator>Legrand, A</creator><creator>Brancatisano, A</creator><creator>Decramer, M</creator><creator>De Troyer, A</creator><general>The Physiological Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19960815</creationdate><title>Rostrocaudal gradient of electrical activation in the parasternal intercostal muscles of the dog</title><author>Legrand, A ; Brancatisano, A ; Decramer, M ; De Troyer, A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5697-abeceb88e0ae5aeaea2e2f29202fd84eba07a6fc3f1d4463801077022630a28f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1996</creationdate><topic>Animals</topic><topic>Dogs</topic><topic>Electromyography</topic><topic>Intercostal Muscles - physiology</topic><topic>Respiration - physiology</topic><topic>Rhizotomy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Legrand, A</creatorcontrib><creatorcontrib>Brancatisano, A</creatorcontrib><creatorcontrib>Decramer, M</creatorcontrib><creatorcontrib>De Troyer, A</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>The Journal of physiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Legrand, A</au><au>Brancatisano, A</au><au>Decramer, M</au><au>De Troyer, A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Rostrocaudal gradient of electrical activation in the parasternal intercostal muscles of the dog</atitle><jtitle>The Journal of physiology</jtitle><addtitle>J Physiol</addtitle><date>1996-08-15</date><risdate>1996</risdate><volume>495</volume><issue>Pt 1</issue><spage>247</spage><epage>254</epage><pages>247-254</pages><issn>0022-3751</issn><eissn>1469-7793</eissn><notes>ObjectType-Article-1</notes><notes>SourceType-Scholarly Journals-1</notes><notes>ObjectType-Feature-2</notes><notes>content type line 23</notes><abstract>1. Because the inspiratory mechanical advantage of the canine parasternal intercostal muscles is greatest in the third interspace
and decreases gradually in the caudal direction, the electromyograms of these muscles in interspaces 3, 5 and 7 have been
recorded in anaesthetized, spontaneously breathing dogs. Each activity was expressed as a percentage of the activity measured
during tetanic, supramaximal stimulation of the internal intercostal nerve (maximal activity). 2. Parasternal inspiratory
activity during resting, room air breathing was invariably greater in the third than in the fifth interspace (62.0 +/- 6.0
vs. 41.3 +/- 4.6% of maximal activity; P < 0.001) and smallest in the seventh interspace (22.8 +/- 2.7% of maximal activity;
P < 0.001). This distribution of activity persisted during hyperoxic hypercapnia and during breathing against increased inspiratory
airflow resistance. 3. This rostrocaudal distribution of activity also persisted after complete paralysis of the diaphragm
as well as after deafferentation of the ribcage. 4. Studies of the distribution of the muscle fibre types indicated that the
parasternal intercostals in all interspaces had a higher proportion of slow-twitch oxidative (SO; type I) fibres than fast-twitch
oxidative-glycolytic (FOG; type II a) fibres. 5. Thus the topographic distribution of parasternal inspiratory activity along
the rostrocaudal axis of the ribcage is precisely matched with the topographic distribution of mechanical advantage. This
extraordinarily effective pattern of activation probably results from the unequal distribution of central inputs throughout
the parasternal motoneurone pool.</abstract><cop>England</cop><pub>The Physiological Society</pub><pmid>8866367</pmid><doi>10.1113/jphysiol.1996.sp021589</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| issn | 0022-3751 1469-7793 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1160740 |
| source | PubMed Central |
| subjects | Animals Dogs Electromyography Intercostal Muscles - physiology Respiration - physiology Rhizotomy |
| title | Rostrocaudal gradient of electrical activation in the parasternal intercostal muscles of the dog |
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