A Case of Diltiazem-Induced Pustular Rash in an 83-Year-Old Female

Acute generalized exanthematous pustulosis (AGEP) is a rare, acute skin eruption characterized by the development of numerous nonfollicular sterile pustules. Most cases are caused by drug reactions, among which Diltiazem has been incriminated. Herein, we present an 83-year-old female who presented f...

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Published in:Case reports in dermatological medicine 2024, Vol.2024, p.9547206
Main Authors: Bangolo, Ayrton I, Yelton-Torres, Karen, Mahajan, Atharv, Patel, Vrusha, Sajjad, Laiba, Ansong, Prince Ofori, Kashyap, Monisha, Batura, Umesh, Ravulapalli, Madhavi, Perera, Ayodya, Weissman, Simcha
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creator Bangolo, Ayrton I
Yelton-Torres, Karen
Mahajan, Atharv
Patel, Vrusha
Sajjad, Laiba
Ansong, Prince Ofori
Kashyap, Monisha
Batura, Umesh
Ravulapalli, Madhavi
Perera, Ayodya
Weissman, Simcha
description Acute generalized exanthematous pustulosis (AGEP) is a rare, acute skin eruption characterized by the development of numerous nonfollicular sterile pustules. Most cases are caused by drug reactions, among which Diltiazem has been incriminated. Herein, we present an 83-year-old female who presented for evaluation of generalized skin rash 3 days after initiation of Diltiazem. She was eventually diagnosed with AGEP, Diltiazem was discontinued, and systemic steroids were administered with the resolution of symptoms. This case report has the objective of encouraging clinicians to include AGEP in the differential diagnosis of skin eruption following the initiation of Diltiazem.
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title A Case of Diltiazem-Induced Pustular Rash in an 83-Year-Old Female
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