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Can coronary angiography predict the site of a subsequent myocardial infarction in patients with mild-to-moderate coronary artery disease?
To help determine if coronary angiography can predict the site of a future coronary occlusion that will produce a myocardial infarction, the coronary angiograms of 42 consecutive patients who had undergone coronary angiography both before and up to a month after suffering an acute myocardial infarct...
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Published in: | Circulation (New York, N.Y.) N.Y.), 1988-11, Vol.78 (5), p.1157-1166 |
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container_title | Circulation (New York, N.Y.) |
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creator | LITTLE, W. C CONSTANTINESCU, M APPLEGATE, R. J KUTCHER, M. A BURROWS, M. T KAHL, F. R SANTAMORE, W. P |
description | To help determine if coronary angiography can predict the site of a future coronary occlusion that will produce a myocardial infarction, the coronary angiograms of 42 consecutive patients who had undergone coronary angiography both before and up to a month after suffering an acute myocardial infarction were evaluated. Twenty-nine patients had a newly occluded coronary artery. Twenty-five of these 29 patients had at least one artery with a greater than 50% stenosis on the initial angiogram. However, in 19 of 29 (66%) patients, the artery that subsequently occluded had less than a 50% stenosis on the first angiogram, and in 28 of 29 (97%), the stenosis was less than 70%. In every patient, at least some irregularity of the coronary wall was present on the first angiogram at the site of the subsequent coronary obstruction. In only 10 of the 29 (34%) did the infarction occur due to occlusion of the artery that previously contained the most severe stenosis. Furthermore, no correlation existed between the severity of the initial coronary stenosis and the time from the first catheterization until the infarction (r2 = 0.0005, p = NS). These data suggest that assessment of the angiographic severity of coronary stenosis may be inadequate to accurately predict the time or location of a subsequent coronary occlusion that will produce a myocardial infarction. |
doi_str_mv | 10.1161/01.CIR.78.5.1157 |
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C ; CONSTANTINESCU, M ; APPLEGATE, R. J ; KUTCHER, M. A ; BURROWS, M. T ; KAHL, F. R ; SANTAMORE, W. P</creator><creatorcontrib>LITTLE, W. C ; CONSTANTINESCU, M ; APPLEGATE, R. J ; KUTCHER, M. A ; BURROWS, M. T ; KAHL, F. R ; SANTAMORE, W. P</creatorcontrib><description>To help determine if coronary angiography can predict the site of a future coronary occlusion that will produce a myocardial infarction, the coronary angiograms of 42 consecutive patients who had undergone coronary angiography both before and up to a month after suffering an acute myocardial infarction were evaluated. Twenty-nine patients had a newly occluded coronary artery. Twenty-five of these 29 patients had at least one artery with a greater than 50% stenosis on the initial angiogram. However, in 19 of 29 (66%) patients, the artery that subsequently occluded had less than a 50% stenosis on the first angiogram, and in 28 of 29 (97%), the stenosis was less than 70%. In every patient, at least some irregularity of the coronary wall was present on the first angiogram at the site of the subsequent coronary obstruction. In only 10 of the 29 (34%) did the infarction occur due to occlusion of the artery that previously contained the most severe stenosis. Furthermore, no correlation existed between the severity of the initial coronary stenosis and the time from the first catheterization until the infarction (r2 = 0.0005, p = NS). These data suggest that assessment of the angiographic severity of coronary stenosis may be inadequate to accurately predict the time or location of a subsequent coronary occlusion that will produce a myocardial infarction.</description><identifier>ISSN: 0009-7322</identifier><identifier>EISSN: 1524-4539</identifier><identifier>DOI: 10.1161/01.CIR.78.5.1157</identifier><identifier>PMID: 3180375</identifier><identifier>CODEN: CIRCAZ</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins</publisher><subject>Adult ; Aged ; Biological and medical sciences ; Cardiology. Vascular system ; Coronary Disease - complications ; Coronary Disease - diagnostic imaging ; Coronary Disease - pathology ; Coronary heart disease ; Heart ; Humans ; Male ; Medical sciences ; Middle Aged ; Myocardial Infarction - diagnostic imaging ; Myocardial Infarction - etiology ; Predictive Value of Tests ; Radiography</subject><ispartof>Circulation (New York, N.Y.), 1988-11, Vol.78 (5), p.1157-1166</ispartof><rights>1989 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c411t-3e0c3ad07d790453979d6fceea9fda5dc03719dddf19db0d6beae23678ddced53</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,786,790,27957,27958</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=6990134$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3180375$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>LITTLE, W. C</creatorcontrib><creatorcontrib>CONSTANTINESCU, M</creatorcontrib><creatorcontrib>APPLEGATE, R. J</creatorcontrib><creatorcontrib>KUTCHER, M. A</creatorcontrib><creatorcontrib>BURROWS, M. T</creatorcontrib><creatorcontrib>KAHL, F. R</creatorcontrib><creatorcontrib>SANTAMORE, W. P</creatorcontrib><title>Can coronary angiography predict the site of a subsequent myocardial infarction in patients with mild-to-moderate coronary artery disease?</title><title>Circulation (New York, N.Y.)</title><addtitle>Circulation</addtitle><description>To help determine if coronary angiography can predict the site of a future coronary occlusion that will produce a myocardial infarction, the coronary angiograms of 42 consecutive patients who had undergone coronary angiography both before and up to a month after suffering an acute myocardial infarction were evaluated. Twenty-nine patients had a newly occluded coronary artery. Twenty-five of these 29 patients had at least one artery with a greater than 50% stenosis on the initial angiogram. However, in 19 of 29 (66%) patients, the artery that subsequently occluded had less than a 50% stenosis on the first angiogram, and in 28 of 29 (97%), the stenosis was less than 70%. In every patient, at least some irregularity of the coronary wall was present on the first angiogram at the site of the subsequent coronary obstruction. In only 10 of the 29 (34%) did the infarction occur due to occlusion of the artery that previously contained the most severe stenosis. Furthermore, no correlation existed between the severity of the initial coronary stenosis and the time from the first catheterization until the infarction (r2 = 0.0005, p = NS). These data suggest that assessment of the angiographic severity of coronary stenosis may be inadequate to accurately predict the time or location of a subsequent coronary occlusion that will produce a myocardial infarction.</description><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Cardiology. Vascular system</subject><subject>Coronary Disease - complications</subject><subject>Coronary Disease - diagnostic imaging</subject><subject>Coronary Disease - pathology</subject><subject>Coronary heart disease</subject><subject>Heart</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Myocardial Infarction - diagnostic imaging</subject><subject>Myocardial Infarction - etiology</subject><subject>Predictive Value of Tests</subject><subject>Radiography</subject><issn>0009-7322</issn><issn>1524-4539</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><recordid>eNpFUMFq3DAQFaEh3Sa551LQoeTmrbSyLftUytI0CwuFkJzFrGacVbEtV5Ip-wv56mjJklw0M5r3nvQeYzdSLKWs5Xchl-vNw1I3yypfVPqMLWS1KouyUu0nthBCtIVWq9Vn9iXGv3msla4u2IWSjcjdgr2sYeTWBz9COHAYn51_DjDtD3wKhM4mnvbEo0vEfceBx3kX6d9MY-LDwVsI6KDnbuwg2OT8mFs-QXIZEPl_l_Z8cD0WyReDRwqQdT5eC4lyQRcJIv24Yucd9JGuT_WSPd39elzfF9s_vzfrn9vCllKmQpGwClBo1K04-tQt1p0lgrZDqNBmY7JFxC6fO4H1joBWqtYNoiWs1CW7fdOdgs9OYjKDi5b6HkbyczS6KZtGC5WB4g1og48xUGem4Ib8cyOFOcZvhDQ5_swwlTnGnylfT9rzbiB8J5zyzvtvpz1EC30XYLQuvsPqthVSleoVsEaRvQ</recordid><startdate>19881101</startdate><enddate>19881101</enddate><creator>LITTLE, W. C</creator><creator>CONSTANTINESCU, M</creator><creator>APPLEGATE, R. J</creator><creator>KUTCHER, M. A</creator><creator>BURROWS, M. T</creator><creator>KAHL, F. R</creator><creator>SANTAMORE, W. P</creator><general>Lippincott Williams & Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19881101</creationdate><title>Can coronary angiography predict the site of a subsequent myocardial infarction in patients with mild-to-moderate coronary artery disease?</title><author>LITTLE, W. C ; CONSTANTINESCU, M ; APPLEGATE, R. J ; KUTCHER, M. A ; BURROWS, M. T ; KAHL, F. R ; SANTAMORE, W. 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C</creatorcontrib><creatorcontrib>CONSTANTINESCU, M</creatorcontrib><creatorcontrib>APPLEGATE, R. J</creatorcontrib><creatorcontrib>KUTCHER, M. A</creatorcontrib><creatorcontrib>BURROWS, M. T</creatorcontrib><creatorcontrib>KAHL, F. R</creatorcontrib><creatorcontrib>SANTAMORE, W. P</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Circulation (New York, N.Y.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>LITTLE, W. C</au><au>CONSTANTINESCU, M</au><au>APPLEGATE, R. J</au><au>KUTCHER, M. A</au><au>BURROWS, M. T</au><au>KAHL, F. R</au><au>SANTAMORE, W. P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Can coronary angiography predict the site of a subsequent myocardial infarction in patients with mild-to-moderate coronary artery disease?</atitle><jtitle>Circulation (New York, N.Y.)</jtitle><addtitle>Circulation</addtitle><date>1988-11-01</date><risdate>1988</risdate><volume>78</volume><issue>5</issue><spage>1157</spage><epage>1166</epage><pages>1157-1166</pages><issn>0009-7322</issn><eissn>1524-4539</eissn><coden>CIRCAZ</coden><notes>ObjectType-Article-1</notes><notes>SourceType-Scholarly Journals-1</notes><notes>ObjectType-Feature-2</notes><notes>content type line 23</notes><abstract>To help determine if coronary angiography can predict the site of a future coronary occlusion that will produce a myocardial infarction, the coronary angiograms of 42 consecutive patients who had undergone coronary angiography both before and up to a month after suffering an acute myocardial infarction were evaluated. Twenty-nine patients had a newly occluded coronary artery. Twenty-five of these 29 patients had at least one artery with a greater than 50% stenosis on the initial angiogram. However, in 19 of 29 (66%) patients, the artery that subsequently occluded had less than a 50% stenosis on the first angiogram, and in 28 of 29 (97%), the stenosis was less than 70%. In every patient, at least some irregularity of the coronary wall was present on the first angiogram at the site of the subsequent coronary obstruction. In only 10 of the 29 (34%) did the infarction occur due to occlusion of the artery that previously contained the most severe stenosis. Furthermore, no correlation existed between the severity of the initial coronary stenosis and the time from the first catheterization until the infarction (r2 = 0.0005, p = NS). These data suggest that assessment of the angiographic severity of coronary stenosis may be inadequate to accurately predict the time or location of a subsequent coronary occlusion that will produce a myocardial infarction.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins</pub><pmid>3180375</pmid><doi>10.1161/01.CIR.78.5.1157</doi><tpages>10</tpages></addata></record> |
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subjects | Adult Aged Biological and medical sciences Cardiology. Vascular system Coronary Disease - complications Coronary Disease - diagnostic imaging Coronary Disease - pathology Coronary heart disease Heart Humans Male Medical sciences Middle Aged Myocardial Infarction - diagnostic imaging Myocardial Infarction - etiology Predictive Value of Tests Radiography |
title | Can coronary angiography predict the site of a subsequent myocardial infarction in patients with mild-to-moderate coronary artery disease? |
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