Effect of chronic stress during early postnatal ontogeny on structural characteristics of the myocardium and glomerular apparatus of the kidneys in NISAG rats

We studied structural characteristics of the myocardium and glomerular apparatus of the kidneys in 3-week- and 6-month-old male NISAG rats (hereditary stress-induced arterial hypertension) subjected to handling on days 1-21 of postnatal ontogeny. The animals were daily isolated from mothers for 10 m...

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2003-07, Vol.136 (1), p.22-25
Main Authors: Shmerling, M D, Filyushina, E E, Korostyshevskaya, I M, Lazarev, V A, Maksimov, V F, Buzueva, I I, Kudryashova, D R, Markel', A L, Yakobson, G S
Format: Article
Language:English
Subjects:
Animals
Blood Pressure
Body Weight
Handling (Psychology)
Hypertension - pathology
Kidney - growth & development
Kidney - metabolism
Kidney - pathology
Kidney Diseases - pathology
Kidney Glomerulus - metabolism
Kidney Glomerulus - pathology
Male
Myocardium - pathology
Rats
Stress, Physiological
Time Factors
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Summary:We studied structural characteristics of the myocardium and glomerular apparatus of the kidneys in 3-week- and 6-month-old male NISAG rats (hereditary stress-induced arterial hypertension) subjected to handling on days 1-21 of postnatal ontogeny. The animals were daily isolated from mothers for 10 min. Handling did not modulate the development of arterial hypertension and typical morphological signs in the myocardium and kidneys.
ISSN:0007-4888
1573-8221
DOI:10.1023/A:1026072309673