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Detection of catechol using mixed Langmuir-Blodgett films of a phospholipid and phthalocyanines as voltammetric sensors
The combination of metallic phthalocyanines (MPcs) and biomolecules has been explored in the literature either as mimetic systems to investigate molecular interactions or as supporting layers to immobilize biomolecules. Here, Langmuir-Blodgett (LB) films containing the phospholipid dimyristoyl phosp...
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| Published in: | Analyst (London) 2010-01, Vol.135 (1), p.2591-2599 |
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| creator | Alessio, Priscila Pavinatto, Felippe J Oliveira Jr, Osvaldo N De Saja Saez, Jose Antonio Constantino, Carlos J. L Rodríguez-Méndez, Maria Luz |
| description | The combination of metallic phthalocyanines (MPcs) and biomolecules has been explored in the literature either as mimetic systems to investigate molecular interactions or as supporting layers to immobilize biomolecules. Here, Langmuir-Blodgett (LB) films containing the phospholipid dimyristoyl phosphatidic acid (DMPA) mixed either with iron phthalocyanine (FePc) or with lutetium bisphthalocyanine (LuPc
2
) were applied as ITO modified-electrodes in the detection of catechol using cyclic voltammetry. The mixed Langmuir films of FePc + DMPA and LuPc
2
+ DMPA displayed surface-pressure isotherms with no evidence of molecular-level interactions. The Fourier Transform Infrared (FTIR) spectra of the multilayer LB films confirmed the lack of interaction between the components. The DMPA and the FePc molecules were found to be oriented perpendicularly to the substrate, while LuPc
2
molecules were randomly organized. The phospholipid matrix induced a remarkable electrocatalytic effect on the phthalocyanines; as a result the mixed LB films deposited on ITO could be used to detect catechol with detection limits of 4.30 × 10
−7
and 3.34 × 10
−7
M for FePc + DMPA and LuPc
2
+ DMPA, respectively. Results from kinetics experiments revealed that ion diffusion dominated the response of the modified electrodes. The sensitivity was comparable to that of other non-enzymatic sensors, which is sufficient to detect catechol in the food industry. The higher stability of the electrochemical response of the LB films and the ability to control the molecular architecture are promising for further studies with incorporation of biomolecules.
Phospholipids and phthalocyanines processed as Langmuir-Blodgett films for modification of electrodes and voltammetric detection of catechol. |
| doi_str_mv | 10.1039/c0an00159g |
| format | article |
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2
) were applied as ITO modified-electrodes in the detection of catechol using cyclic voltammetry. The mixed Langmuir films of FePc + DMPA and LuPc
2
+ DMPA displayed surface-pressure isotherms with no evidence of molecular-level interactions. The Fourier Transform Infrared (FTIR) spectra of the multilayer LB films confirmed the lack of interaction between the components. The DMPA and the FePc molecules were found to be oriented perpendicularly to the substrate, while LuPc
2
molecules were randomly organized. The phospholipid matrix induced a remarkable electrocatalytic effect on the phthalocyanines; as a result the mixed LB films deposited on ITO could be used to detect catechol with detection limits of 4.30 × 10
−7
and 3.34 × 10
−7
M for FePc + DMPA and LuPc
2
+ DMPA, respectively. Results from kinetics experiments revealed that ion diffusion dominated the response of the modified electrodes. The sensitivity was comparable to that of other non-enzymatic sensors, which is sufficient to detect catechol in the food industry. The higher stability of the electrochemical response of the LB films and the ability to control the molecular architecture are promising for further studies with incorporation of biomolecules.
Phospholipids and phthalocyanines processed as Langmuir-Blodgett films for modification of electrodes and voltammetric detection of catechol.</description><identifier>ISSN: 0003-2654</identifier><identifier>EISSN: 1364-5528</identifier><identifier>DOI: 10.1039/c0an00159g</identifier><identifier>PMID: 20714515</identifier><identifier>CODEN: ANALAO</identifier><language>eng</language><publisher>Cambridge: Royal Society of Chemistry</publisher><subject>Analytical chemistry ; Biomolecules ; Catechol ; Catechols - analysis ; Chemistry ; Electrochemical methods ; Electrochemical Techniques - methods ; Electrodes ; Exact sciences and technology ; Ferrous Compounds - chemistry ; General, instrumentation ; Glycerophospholipids - chemistry ; Indium tin oxide ; Indoles - chemistry ; Kinetics ; Langmuir-Blodgett films ; Phospholipids ; Sensors ; Spectrometric and optical methods ; Spectroscopy, Fourier Transform Infrared ; Stability</subject><ispartof>Analyst (London), 2010-01, Vol.135 (1), p.2591-2599</ispartof><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c498t-3013e12e57af4e4df640bec31b787c098989c20eca5560baf5d45cf8d1c543e33</citedby><cites>FETCH-LOGICAL-c498t-3013e12e57af4e4df640bec31b787c098989c20eca5560baf5d45cf8d1c543e33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,786,790,27957,27958</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23336607$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20714515$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Alessio, Priscila</creatorcontrib><creatorcontrib>Pavinatto, Felippe J</creatorcontrib><creatorcontrib>Oliveira Jr, Osvaldo N</creatorcontrib><creatorcontrib>De Saja Saez, Jose Antonio</creatorcontrib><creatorcontrib>Constantino, Carlos J. L</creatorcontrib><creatorcontrib>Rodríguez-Méndez, Maria Luz</creatorcontrib><title>Detection of catechol using mixed Langmuir-Blodgett films of a phospholipid and phthalocyanines as voltammetric sensors</title><title>Analyst (London)</title><addtitle>Analyst</addtitle><description>The combination of metallic phthalocyanines (MPcs) and biomolecules has been explored in the literature either as mimetic systems to investigate molecular interactions or as supporting layers to immobilize biomolecules. Here, Langmuir-Blodgett (LB) films containing the phospholipid dimyristoyl phosphatidic acid (DMPA) mixed either with iron phthalocyanine (FePc) or with lutetium bisphthalocyanine (LuPc
2
) were applied as ITO modified-electrodes in the detection of catechol using cyclic voltammetry. The mixed Langmuir films of FePc + DMPA and LuPc
2
+ DMPA displayed surface-pressure isotherms with no evidence of molecular-level interactions. The Fourier Transform Infrared (FTIR) spectra of the multilayer LB films confirmed the lack of interaction between the components. The DMPA and the FePc molecules were found to be oriented perpendicularly to the substrate, while LuPc
2
molecules were randomly organized. The phospholipid matrix induced a remarkable electrocatalytic effect on the phthalocyanines; as a result the mixed LB films deposited on ITO could be used to detect catechol with detection limits of 4.30 × 10
−7
and 3.34 × 10
−7
M for FePc + DMPA and LuPc
2
+ DMPA, respectively. Results from kinetics experiments revealed that ion diffusion dominated the response of the modified electrodes. The sensitivity was comparable to that of other non-enzymatic sensors, which is sufficient to detect catechol in the food industry. The higher stability of the electrochemical response of the LB films and the ability to control the molecular architecture are promising for further studies with incorporation of biomolecules.
Phospholipids and phthalocyanines processed as Langmuir-Blodgett films for modification of electrodes and voltammetric detection of catechol.</description><subject>Analytical chemistry</subject><subject>Biomolecules</subject><subject>Catechol</subject><subject>Catechols - analysis</subject><subject>Chemistry</subject><subject>Electrochemical methods</subject><subject>Electrochemical Techniques - methods</subject><subject>Electrodes</subject><subject>Exact sciences and technology</subject><subject>Ferrous Compounds - chemistry</subject><subject>General, instrumentation</subject><subject>Glycerophospholipids - chemistry</subject><subject>Indium tin oxide</subject><subject>Indoles - chemistry</subject><subject>Kinetics</subject><subject>Langmuir-Blodgett films</subject><subject>Phospholipids</subject><subject>Sensors</subject><subject>Spectrometric and optical methods</subject><subject>Spectroscopy, Fourier Transform Infrared</subject><subject>Stability</subject><issn>0003-2654</issn><issn>1364-5528</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><recordid>eNqF0U2LFDEQBuAgijuuXrwr8SCC0FrpJP1xXNdPGPCi5yaTrsxE0kmbSqv77-1lxl28KCGESj1UHV7GHgt4JUD2ry2YCCB0v7_DNkI2qtK67u6yDQDIqm60OmMPiL6tpQAN99lZDa1QWugN-_kWC9riU-TJcWvW4pACX8jHPZ_8Lxz51sT9tPhcvQlp3GMp3Pkw0bU3fD4kWm_wsx-5ieP6UQ4mJHtloo9I3BD_kUIx04Qle8sJI6VMD9k9ZwLho9N7zr6-f_fl8mO1_fzh0-XFtrKq70olQUgUNerWOIVqdI2CHVopdm3XWui79dga0BqtG9gZp0elretGYbWSKOU5e3GcO-f0fUEqw-TJYggmYlpo6FSvVC37_8tWa9EIgH6VL4_S5kSU0Q1z9pPJV4OA4TqR4TaRFT89jV12E4439E8EK3h-AoasCS6baD3dOill00C7uidHl8nedP9a9Oxf_WEenfwNMs6qlA</recordid><startdate>20100101</startdate><enddate>20100101</enddate><creator>Alessio, Priscila</creator><creator>Pavinatto, Felippe J</creator><creator>Oliveira Jr, Osvaldo N</creator><creator>De Saja Saez, Jose Antonio</creator><creator>Constantino, Carlos J. L</creator><creator>Rodríguez-Méndez, Maria Luz</creator><general>Royal Society of Chemistry</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7SR</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope><scope>L7M</scope></search><sort><creationdate>20100101</creationdate><title>Detection of catechol using mixed Langmuir-Blodgett films of a phospholipid and phthalocyanines as voltammetric sensors</title><author>Alessio, Priscila ; Pavinatto, Felippe J ; Oliveira Jr, Osvaldo N ; De Saja Saez, Jose Antonio ; Constantino, Carlos J. L ; Rodríguez-Méndez, Maria Luz</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c498t-3013e12e57af4e4df640bec31b787c098989c20eca5560baf5d45cf8d1c543e33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Analytical chemistry</topic><topic>Biomolecules</topic><topic>Catechol</topic><topic>Catechols - analysis</topic><topic>Chemistry</topic><topic>Electrochemical methods</topic><topic>Electrochemical Techniques - methods</topic><topic>Electrodes</topic><topic>Exact sciences and technology</topic><topic>Ferrous Compounds - chemistry</topic><topic>General, instrumentation</topic><topic>Glycerophospholipids - chemistry</topic><topic>Indium tin oxide</topic><topic>Indoles - chemistry</topic><topic>Kinetics</topic><topic>Langmuir-Blodgett films</topic><topic>Phospholipids</topic><topic>Sensors</topic><topic>Spectrometric and optical methods</topic><topic>Spectroscopy, Fourier Transform Infrared</topic><topic>Stability</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Alessio, Priscila</creatorcontrib><creatorcontrib>Pavinatto, Felippe J</creatorcontrib><creatorcontrib>Oliveira Jr, Osvaldo N</creatorcontrib><creatorcontrib>De Saja Saez, Jose Antonio</creatorcontrib><creatorcontrib>Constantino, Carlos J. L</creatorcontrib><creatorcontrib>Rodríguez-Méndez, Maria Luz</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Engineered Materials Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><jtitle>Analyst (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Alessio, Priscila</au><au>Pavinatto, Felippe J</au><au>Oliveira Jr, Osvaldo N</au><au>De Saja Saez, Jose Antonio</au><au>Constantino, Carlos J. L</au><au>Rodríguez-Méndez, Maria Luz</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Detection of catechol using mixed Langmuir-Blodgett films of a phospholipid and phthalocyanines as voltammetric sensors</atitle><jtitle>Analyst (London)</jtitle><addtitle>Analyst</addtitle><date>2010-01-01</date><risdate>2010</risdate><volume>135</volume><issue>1</issue><spage>2591</spage><epage>2599</epage><pages>2591-2599</pages><issn>0003-2654</issn><eissn>1364-5528</eissn><coden>ANALAO</coden><notes>ObjectType-Article-1</notes><notes>SourceType-Scholarly Journals-1</notes><notes>ObjectType-Feature-2</notes><notes>content type line 23</notes><notes>ObjectType-Article-2</notes><notes>ObjectType-Feature-1</notes><abstract>The combination of metallic phthalocyanines (MPcs) and biomolecules has been explored in the literature either as mimetic systems to investigate molecular interactions or as supporting layers to immobilize biomolecules. Here, Langmuir-Blodgett (LB) films containing the phospholipid dimyristoyl phosphatidic acid (DMPA) mixed either with iron phthalocyanine (FePc) or with lutetium bisphthalocyanine (LuPc
2
) were applied as ITO modified-electrodes in the detection of catechol using cyclic voltammetry. The mixed Langmuir films of FePc + DMPA and LuPc
2
+ DMPA displayed surface-pressure isotherms with no evidence of molecular-level interactions. The Fourier Transform Infrared (FTIR) spectra of the multilayer LB films confirmed the lack of interaction between the components. The DMPA and the FePc molecules were found to be oriented perpendicularly to the substrate, while LuPc
2
molecules were randomly organized. The phospholipid matrix induced a remarkable electrocatalytic effect on the phthalocyanines; as a result the mixed LB films deposited on ITO could be used to detect catechol with detection limits of 4.30 × 10
−7
and 3.34 × 10
−7
M for FePc + DMPA and LuPc
2
+ DMPA, respectively. Results from kinetics experiments revealed that ion diffusion dominated the response of the modified electrodes. The sensitivity was comparable to that of other non-enzymatic sensors, which is sufficient to detect catechol in the food industry. The higher stability of the electrochemical response of the LB films and the ability to control the molecular architecture are promising for further studies with incorporation of biomolecules.
Phospholipids and phthalocyanines processed as Langmuir-Blodgett films for modification of electrodes and voltammetric detection of catechol.</abstract><cop>Cambridge</cop><pub>Royal Society of Chemistry</pub><pmid>20714515</pmid><doi>10.1039/c0an00159g</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0003-2654 |
| ispartof | Analyst (London), 2010-01, Vol.135 (1), p.2591-2599 |
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| language | eng |
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| source | Royal Society of Chemistry:Jisc Collections:Royal Society of Chemistry Read and Publish 2022-2024 (reading list) |
| subjects | Analytical chemistry Biomolecules Catechol Catechols - analysis Chemistry Electrochemical methods Electrochemical Techniques - methods Electrodes Exact sciences and technology Ferrous Compounds - chemistry General, instrumentation Glycerophospholipids - chemistry Indium tin oxide Indoles - chemistry Kinetics Langmuir-Blodgett films Phospholipids Sensors Spectrometric and optical methods Spectroscopy, Fourier Transform Infrared Stability |
| title | Detection of catechol using mixed Langmuir-Blodgett films of a phospholipid and phthalocyanines as voltammetric sensors |
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