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Chondroblastoma of the lumbar spine with cauda equina syndrome
Case report. To describe the clinical presentations, radiological features and clinical progress of a rare case of chondroblastoma of the lumbar spine. Regional Hospital, Hong Kong, China. A 54-year-old male patient presented with low back pain and left sciatica. X-ray and MRI revealed tumour infilt...
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| Published in: | Spinal cord 2003-06, Vol.41 (6), p.359-364 |
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| creator | CHUNG, O. M YIP, S. F NGAN, K. C NG, W. F |
| description | Case report.
To describe the clinical presentations, radiological features and clinical progress of a rare case of chondroblastoma of the lumbar spine.
Regional Hospital, Hong Kong, China.
A 54-year-old male patient presented with low back pain and left sciatica. X-ray and MRI revealed tumour infiltration of the fifth lumbar vertebrae and left paraspinal muscles, which was found to be a chondroblastoma by repeated open biopsies. The tumour was removed surgically by combined anterior and posterior approaches, followed by spinal fusion and instrumentation.
The anterior tricortical bone graft was complicated with fracture and nonunion. Surgical re-exploration confirmed local recurrence of tumour macroscopically and histologically. The patient developed symptoms and signs of cauda equina syndrome gradually despite repeated surgery and irradiation. The patient eventually died of complications of local recurrence and neurological deficit at 3 years and 8 months after the first operation.
This is the first case report of chondroblastoma of the lumbar spine. The clinical profile of this patient and the evidence from the literature review suggests that spinal chondroblastoma has a very aggressive behaviour with high recurrence and mortality rate. |
| doi_str_mv | 10.1038/sj.sc.3101458 |
| format | article |
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To describe the clinical presentations, radiological features and clinical progress of a rare case of chondroblastoma of the lumbar spine.
Regional Hospital, Hong Kong, China.
A 54-year-old male patient presented with low back pain and left sciatica. X-ray and MRI revealed tumour infiltration of the fifth lumbar vertebrae and left paraspinal muscles, which was found to be a chondroblastoma by repeated open biopsies. The tumour was removed surgically by combined anterior and posterior approaches, followed by spinal fusion and instrumentation.
The anterior tricortical bone graft was complicated with fracture and nonunion. Surgical re-exploration confirmed local recurrence of tumour macroscopically and histologically. The patient developed symptoms and signs of cauda equina syndrome gradually despite repeated surgery and irradiation. The patient eventually died of complications of local recurrence and neurological deficit at 3 years and 8 months after the first operation.
This is the first case report of chondroblastoma of the lumbar spine. The clinical profile of this patient and the evidence from the literature review suggests that spinal chondroblastoma has a very aggressive behaviour with high recurrence and mortality rate.</description><identifier>ISSN: 1362-4393</identifier><identifier>EISSN: 1476-5624</identifier><identifier>DOI: 10.1038/sj.sc.3101458</identifier><identifier>PMID: 12746743</identifier><identifier>CODEN: SPCOFM</identifier><language>eng</language><publisher>London: Nature Publishing</publisher><subject>Biological and medical sciences ; Bone Neoplasms - complications ; Bone Neoplasms - mortality ; Bone Neoplasms - pathology ; Bone Neoplasms - surgery ; Cauda Equina Syndrome ; Chondroblastoma - complications ; Chondroblastoma - mortality ; Chondroblastoma - pathology ; Chondroblastoma - surgery ; Diseases of the osteoarticular system ; Diseases of the spine ; Humans ; Lumbar Vertebrae ; Magnetic Resonance Imaging - methods ; Male ; Medical sciences ; Middle Aged ; Neoplasm Recurrence, Local ; Polyradiculopathy - complications ; Polyradiculopathy - mortality ; Polyradiculopathy - pathology ; Postoperative Complications - mortality ; Spinal Fusion - methods ; Tomography, X-Ray Computed - methods ; Tropical medicine</subject><ispartof>Spinal cord, 2003-06, Vol.41 (6), p.359-364</ispartof><rights>2003 INIST-CNRS</rights><rights>Copyright Nature Publishing Group Jun 2003</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c407t-b8225a8eb91bda0f8fe606992b7c4aab3ed486d6859e3108627504e73c249acf3</citedby><cites>FETCH-LOGICAL-c407t-b8225a8eb91bda0f8fe606992b7c4aab3ed486d6859e3108627504e73c249acf3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,786,790,27957,27958</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=14810751$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12746743$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>CHUNG, O. M</creatorcontrib><creatorcontrib>YIP, S. F</creatorcontrib><creatorcontrib>NGAN, K. C</creatorcontrib><creatorcontrib>NG, W. F</creatorcontrib><title>Chondroblastoma of the lumbar spine with cauda equina syndrome</title><title>Spinal cord</title><addtitle>Spinal Cord</addtitle><description>Case report.
To describe the clinical presentations, radiological features and clinical progress of a rare case of chondroblastoma of the lumbar spine.
Regional Hospital, Hong Kong, China.
A 54-year-old male patient presented with low back pain and left sciatica. X-ray and MRI revealed tumour infiltration of the fifth lumbar vertebrae and left paraspinal muscles, which was found to be a chondroblastoma by repeated open biopsies. The tumour was removed surgically by combined anterior and posterior approaches, followed by spinal fusion and instrumentation.
The anterior tricortical bone graft was complicated with fracture and nonunion. Surgical re-exploration confirmed local recurrence of tumour macroscopically and histologically. The patient developed symptoms and signs of cauda equina syndrome gradually despite repeated surgery and irradiation. The patient eventually died of complications of local recurrence and neurological deficit at 3 years and 8 months after the first operation.
This is the first case report of chondroblastoma of the lumbar spine. The clinical profile of this patient and the evidence from the literature review suggests that spinal chondroblastoma has a very aggressive behaviour with high recurrence and mortality rate.</description><subject>Biological and medical sciences</subject><subject>Bone Neoplasms - complications</subject><subject>Bone Neoplasms - mortality</subject><subject>Bone Neoplasms - pathology</subject><subject>Bone Neoplasms - surgery</subject><subject>Cauda Equina Syndrome</subject><subject>Chondroblastoma - complications</subject><subject>Chondroblastoma - mortality</subject><subject>Chondroblastoma - pathology</subject><subject>Chondroblastoma - surgery</subject><subject>Diseases of the osteoarticular system</subject><subject>Diseases of the spine</subject><subject>Humans</subject><subject>Lumbar Vertebrae</subject><subject>Magnetic Resonance Imaging - methods</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Neoplasm Recurrence, Local</subject><subject>Polyradiculopathy - complications</subject><subject>Polyradiculopathy - mortality</subject><subject>Polyradiculopathy - pathology</subject><subject>Postoperative Complications - mortality</subject><subject>Spinal Fusion - methods</subject><subject>Tomography, X-Ray Computed - methods</subject><subject>Tropical medicine</subject><issn>1362-4393</issn><issn>1476-5624</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><recordid>eNpd0EtLxDAQB_Agio_Vo0elCHrrmlfzuAiy-ALBi57DNE3ZLn2smRbZb291q4KnzOE3M5k_IaeMzhkV5hpXc_RzwSiTmdkhh0xqlWaKy92xFoqnUlhxQI4QV5RSy6zZJweMa6m0FIfkZrHs2iJ2eQ3Ydw0kXZn0y5DUQ5NDTHBdtSH5qPpl4mEoIAnvQ9VCgpuvpiYck70Sagwn0zsjb_d3r4vH9Pnl4Wlx-5x6SXWf5obzDEzILcsLoKUpg6LKWp5rLwFyEQppVKFMZsN4ilFcZ1QGLTyXFnwpZuRqO3cdu_chYO-aCn2oa2hDN6DTgltrxktn5OIfXHVDbMe_Oc6t5Ep-o3SLfOwQYyjdOlYNxI1j1H2l6nDl0Lsp1dGfT0OHvAnFn55iHMHlBAA91GWE1lf456RhVGdsdGdb10I_xPALfhZ9AlrriM0</recordid><startdate>20030601</startdate><enddate>20030601</enddate><creator>CHUNG, O. 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M ; YIP, S. F ; NGAN, K. C ; NG, W. F</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c407t-b8225a8eb91bda0f8fe606992b7c4aab3ed486d6859e3108627504e73c249acf3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Biological and medical sciences</topic><topic>Bone Neoplasms - complications</topic><topic>Bone Neoplasms - mortality</topic><topic>Bone Neoplasms - pathology</topic><topic>Bone Neoplasms - surgery</topic><topic>Cauda Equina Syndrome</topic><topic>Chondroblastoma - complications</topic><topic>Chondroblastoma - mortality</topic><topic>Chondroblastoma - pathology</topic><topic>Chondroblastoma - surgery</topic><topic>Diseases of the osteoarticular system</topic><topic>Diseases of the spine</topic><topic>Humans</topic><topic>Lumbar Vertebrae</topic><topic>Magnetic Resonance Imaging - methods</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Neoplasm Recurrence, Local</topic><topic>Polyradiculopathy - complications</topic><topic>Polyradiculopathy - mortality</topic><topic>Polyradiculopathy - pathology</topic><topic>Postoperative Complications - mortality</topic><topic>Spinal Fusion - methods</topic><topic>Tomography, X-Ray Computed - methods</topic><topic>Tropical medicine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>CHUNG, O. 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M</au><au>YIP, S. F</au><au>NGAN, K. C</au><au>NG, W. F</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Chondroblastoma of the lumbar spine with cauda equina syndrome</atitle><jtitle>Spinal cord</jtitle><addtitle>Spinal Cord</addtitle><date>2003-06-01</date><risdate>2003</risdate><volume>41</volume><issue>6</issue><spage>359</spage><epage>364</epage><pages>359-364</pages><issn>1362-4393</issn><eissn>1476-5624</eissn><coden>SPCOFM</coden><notes>ObjectType-Case Study-3</notes><notes>SourceType-Scholarly Journals-1</notes><notes>content type line 23</notes><notes>ObjectType-Review-1</notes><notes>ObjectType-Feature-5</notes><notes>ObjectType-Report-2</notes><notes>ObjectType-Article-4</notes><abstract>Case report.
To describe the clinical presentations, radiological features and clinical progress of a rare case of chondroblastoma of the lumbar spine.
Regional Hospital, Hong Kong, China.
A 54-year-old male patient presented with low back pain and left sciatica. X-ray and MRI revealed tumour infiltration of the fifth lumbar vertebrae and left paraspinal muscles, which was found to be a chondroblastoma by repeated open biopsies. The tumour was removed surgically by combined anterior and posterior approaches, followed by spinal fusion and instrumentation.
The anterior tricortical bone graft was complicated with fracture and nonunion. Surgical re-exploration confirmed local recurrence of tumour macroscopically and histologically. The patient developed symptoms and signs of cauda equina syndrome gradually despite repeated surgery and irradiation. The patient eventually died of complications of local recurrence and neurological deficit at 3 years and 8 months after the first operation.
This is the first case report of chondroblastoma of the lumbar spine. The clinical profile of this patient and the evidence from the literature review suggests that spinal chondroblastoma has a very aggressive behaviour with high recurrence and mortality rate.</abstract><cop>London</cop><pub>Nature Publishing</pub><pmid>12746743</pmid><doi>10.1038/sj.sc.3101458</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| source | SPORTDiscus with Full Text |
| subjects | Biological and medical sciences Bone Neoplasms - complications Bone Neoplasms - mortality Bone Neoplasms - pathology Bone Neoplasms - surgery Cauda Equina Syndrome Chondroblastoma - complications Chondroblastoma - mortality Chondroblastoma - pathology Chondroblastoma - surgery Diseases of the osteoarticular system Diseases of the spine Humans Lumbar Vertebrae Magnetic Resonance Imaging - methods Male Medical sciences Middle Aged Neoplasm Recurrence, Local Polyradiculopathy - complications Polyradiculopathy - mortality Polyradiculopathy - pathology Postoperative Complications - mortality Spinal Fusion - methods Tomography, X-Ray Computed - methods Tropical medicine |
| title | Chondroblastoma of the lumbar spine with cauda equina syndrome |
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