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Low Helicobacter pylori eradication rates with 4- and 7-day regimens in an Iranian population
Background: In Iran, there is insufficient information on the efficacy of Helicobacter pylori eradication regimens shorter than 10 days. This study aims at assessing the efficacy of 4‐ and 7‐day H. pylori eradication regimens in a high‐incidence area of gastric cancer in Iran. Methods: Subjects with...
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| Published in: | Journal of gastroenterology and hepatology 2003-01, Vol.18 (1), p.13-17 |
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| creator | MALEKZADEH, REZA MERAT, SHAHIN DERAKHSHAN, MOHAMMAD-HASSAN SIAVOSHI, FARIDEH YAZDANBOD, ABBAS MIKAELI, JAVAD SOTOUDEMANESH, RASOUL SOTOUDEH, MASOUD FARAHVASH, MOHAMMAD-JAFAR NASSERI-MOGHADDAM, SIAVOSH POURSHAMS, AKRAM DOLATSHAHI, SHAHAB ABEDI, BEHNOOSH BABAEI, MASOUD ARSHI, SHAHNAM MAJIDPOUR, ALI |
| description | Background: In Iran, there is insufficient information on the efficacy of Helicobacter pylori eradication regimens shorter than 10 days. This study aims at assessing the efficacy of 4‐ and 7‐day H. pylori eradication regimens in a high‐incidence area of gastric cancer in Iran.
Methods: Subjects with an endoscopic diagnosis of gastritis, positive urease test, and a histological diagnosis of chronic gastritis were enrolled. Patients were randomly assigned to one of three groups: AOC7 (1000 mg amoxicillin, 20 mg omeprazole, and 500 mg clarithromycin twice daily for 7 days), FOT4 (200 mg furazolidone, 20 mg omeprazole, and 500 mg tetracycline twice daily for 4 days) and FOT7 (the same treatment as the FOT4 group but for 7 days). Sensitivity to these antibiotics was determined in all isolates recovered from culture. The efficacy of eradication was assessed 8 weeks after the end‐of‐treatment by the 14C‐urea breath test.
Results: One hundred and twenty‐eight patients were enrolled in the study. Culture was positive for 84 patients and none of these were resistant to amoxicillin, tetracycline or furazolidone, 1.2% were resistant to clarithromycin and 32.1% to metronidazole. Forty‐five, 41 and 42 patients were randomly allocated to the AOC7, FOT4, and FOT7 groups, respectively. The intention‐to‐treat eradication rates were 35.5, 17.1, and 23.8% for the AOC7, FOT4, and FOT7 groups, respectively.
Conclusion: Treatment regimens of 4 or 7 days are unacceptable for H. pylori infection in Iran, even in the presence of a favorable sensitivity profile.
© 2003 Blackwell Publishing Asia Pty Ltd |
| doi_str_mv | 10.1046/j.1440-1746.2003.02897.x |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_72942907</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>72942907</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4857-cc88afcb0b543263920924c6de4efb30509875ea493ea55d5a1ec0d58dcc42213</originalsourceid><addsrcrecordid>eNqNkE1v0zAYgC0EYmXwF5AvcEv2-iuODxzQBO2mAkKAOCHLcd6AS5pkdqq2_55krbYrp9eyn8e2HkIog5yBLK42OZMSMqZlkXMAkQMvjc4PT8ji4eApWUDJVGYEMxfkRUobAJCg1XNywbhihrNyQX6t-z1dYRt8Xzk_YqTDse1joBhdHbwbQ9_R6EZMdB_GP1Rm1HU11VntjjTi77DFLtHQTbv0JrouTHPoh117b74kzxrXJnx1npfkx8cP369X2frL8ub6_TrzslQ6874sXeMrqJQUvBCGg-HSFzVKbCoBCkypFTppBDqlauUYeqhVWXsvOWfikrw93TvE_m6HabTbkDy2reuw3yWruZHcgJ7A8gT62KcUsbFDDFsXj5aBndPajZ0L2rmgndPa-7T2MKmvz2_sqi3Wj-K55QS8OQMuedc2Uw0f0iMnFQcuZu7diduHFo___QF7u1zNq8nPTn5IIx4efBf_2kILrezPz0v76dvqK-jC2LX4BzOzoxA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>72942907</pqid></control><display><type>article</type><title>Low Helicobacter pylori eradication rates with 4- and 7-day regimens in an Iranian population</title><source>Wiley</source><creator>MALEKZADEH, REZA ; MERAT, SHAHIN ; DERAKHSHAN, MOHAMMAD-HASSAN ; SIAVOSHI, FARIDEH ; YAZDANBOD, ABBAS ; MIKAELI, JAVAD ; SOTOUDEMANESH, RASOUL ; SOTOUDEH, MASOUD ; FARAHVASH, MOHAMMAD-JAFAR ; NASSERI-MOGHADDAM, SIAVOSH ; POURSHAMS, AKRAM ; DOLATSHAHI, SHAHAB ; ABEDI, BEHNOOSH ; BABAEI, MASOUD ; ARSHI, SHAHNAM ; MAJIDPOUR, ALI</creator><creatorcontrib>MALEKZADEH, REZA ; MERAT, SHAHIN ; DERAKHSHAN, MOHAMMAD-HASSAN ; SIAVOSHI, FARIDEH ; YAZDANBOD, ABBAS ; MIKAELI, JAVAD ; SOTOUDEMANESH, RASOUL ; SOTOUDEH, MASOUD ; FARAHVASH, MOHAMMAD-JAFAR ; NASSERI-MOGHADDAM, SIAVOSH ; POURSHAMS, AKRAM ; DOLATSHAHI, SHAHAB ; ABEDI, BEHNOOSH ; BABAEI, MASOUD ; ARSHI, SHAHNAM ; MAJIDPOUR, ALI</creatorcontrib><description>Background: In Iran, there is insufficient information on the efficacy of Helicobacter pylori eradication regimens shorter than 10 days. This study aims at assessing the efficacy of 4‐ and 7‐day H. pylori eradication regimens in a high‐incidence area of gastric cancer in Iran.
Methods: Subjects with an endoscopic diagnosis of gastritis, positive urease test, and a histological diagnosis of chronic gastritis were enrolled. Patients were randomly assigned to one of three groups: AOC7 (1000 mg amoxicillin, 20 mg omeprazole, and 500 mg clarithromycin twice daily for 7 days), FOT4 (200 mg furazolidone, 20 mg omeprazole, and 500 mg tetracycline twice daily for 4 days) and FOT7 (the same treatment as the FOT4 group but for 7 days). Sensitivity to these antibiotics was determined in all isolates recovered from culture. The efficacy of eradication was assessed 8 weeks after the end‐of‐treatment by the 14C‐urea breath test.
Results: One hundred and twenty‐eight patients were enrolled in the study. Culture was positive for 84 patients and none of these were resistant to amoxicillin, tetracycline or furazolidone, 1.2% were resistant to clarithromycin and 32.1% to metronidazole. Forty‐five, 41 and 42 patients were randomly allocated to the AOC7, FOT4, and FOT7 groups, respectively. The intention‐to‐treat eradication rates were 35.5, 17.1, and 23.8% for the AOC7, FOT4, and FOT7 groups, respectively.
Conclusion: Treatment regimens of 4 or 7 days are unacceptable for H. pylori infection in Iran, even in the presence of a favorable sensitivity profile.
© 2003 Blackwell Publishing Asia Pty Ltd</description><identifier>ISSN: 0815-9319</identifier><identifier>EISSN: 1440-1746</identifier><identifier>DOI: 10.1046/j.1440-1746.2003.02897.x</identifier><identifier>PMID: 12519218</identifier><language>eng</language><publisher>Melbourne, Australia: Blackwell Science Pty</publisher><subject>Aged ; Anti-Bacterial Agents - administration & dosage ; Antibacterial agents ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Bacterial diseases ; Bacterial diseases of the digestive system and abdomen ; Biological and medical sciences ; Drug Administration Schedule ; Drug Combinations ; Female ; Helicobacter Infections - drug therapy ; Helicobacter pylori ; Human bacterial diseases ; Humans ; Infectious diseases ; Iran ; Male ; Medical sciences ; Middle Aged ; Pharmacology. Drug treatments ; therapeutics ; Treatment Outcome ; Tropical medicine</subject><ispartof>Journal of gastroenterology and hepatology, 2003-01, Vol.18 (1), p.13-17</ispartof><rights>2003 INIST-CNRS</rights><rights>Copyright 2003 Blackwell Publishing Asia Pty Ltd</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4857-cc88afcb0b543263920924c6de4efb30509875ea493ea55d5a1ec0d58dcc42213</citedby><cites>FETCH-LOGICAL-c4857-cc88afcb0b543263920924c6de4efb30509875ea493ea55d5a1ec0d58dcc42213</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1046%2Fj.1440-1746.2003.02897.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1046%2Fj.1440-1746.2003.02897.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>315,786,790,4043,27956,27957,27958,50923,51032</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=14520238$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12519218$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>MALEKZADEH, REZA</creatorcontrib><creatorcontrib>MERAT, SHAHIN</creatorcontrib><creatorcontrib>DERAKHSHAN, MOHAMMAD-HASSAN</creatorcontrib><creatorcontrib>SIAVOSHI, FARIDEH</creatorcontrib><creatorcontrib>YAZDANBOD, ABBAS</creatorcontrib><creatorcontrib>MIKAELI, JAVAD</creatorcontrib><creatorcontrib>SOTOUDEMANESH, RASOUL</creatorcontrib><creatorcontrib>SOTOUDEH, MASOUD</creatorcontrib><creatorcontrib>FARAHVASH, MOHAMMAD-JAFAR</creatorcontrib><creatorcontrib>NASSERI-MOGHADDAM, SIAVOSH</creatorcontrib><creatorcontrib>POURSHAMS, AKRAM</creatorcontrib><creatorcontrib>DOLATSHAHI, SHAHAB</creatorcontrib><creatorcontrib>ABEDI, BEHNOOSH</creatorcontrib><creatorcontrib>BABAEI, MASOUD</creatorcontrib><creatorcontrib>ARSHI, SHAHNAM</creatorcontrib><creatorcontrib>MAJIDPOUR, ALI</creatorcontrib><title>Low Helicobacter pylori eradication rates with 4- and 7-day regimens in an Iranian population</title><title>Journal of gastroenterology and hepatology</title><addtitle>J Gastroenterol Hepatol</addtitle><description>Background: In Iran, there is insufficient information on the efficacy of Helicobacter pylori eradication regimens shorter than 10 days. This study aims at assessing the efficacy of 4‐ and 7‐day H. pylori eradication regimens in a high‐incidence area of gastric cancer in Iran.
Methods: Subjects with an endoscopic diagnosis of gastritis, positive urease test, and a histological diagnosis of chronic gastritis were enrolled. Patients were randomly assigned to one of three groups: AOC7 (1000 mg amoxicillin, 20 mg omeprazole, and 500 mg clarithromycin twice daily for 7 days), FOT4 (200 mg furazolidone, 20 mg omeprazole, and 500 mg tetracycline twice daily for 4 days) and FOT7 (the same treatment as the FOT4 group but for 7 days). Sensitivity to these antibiotics was determined in all isolates recovered from culture. The efficacy of eradication was assessed 8 weeks after the end‐of‐treatment by the 14C‐urea breath test.
Results: One hundred and twenty‐eight patients were enrolled in the study. Culture was positive for 84 patients and none of these were resistant to amoxicillin, tetracycline or furazolidone, 1.2% were resistant to clarithromycin and 32.1% to metronidazole. Forty‐five, 41 and 42 patients were randomly allocated to the AOC7, FOT4, and FOT7 groups, respectively. The intention‐to‐treat eradication rates were 35.5, 17.1, and 23.8% for the AOC7, FOT4, and FOT7 groups, respectively.
Conclusion: Treatment regimens of 4 or 7 days are unacceptable for H. pylori infection in Iran, even in the presence of a favorable sensitivity profile.
© 2003 Blackwell Publishing Asia Pty Ltd</description><subject>Aged</subject><subject>Anti-Bacterial Agents - administration & dosage</subject><subject>Antibacterial agents</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Bacterial diseases</subject><subject>Bacterial diseases of the digestive system and abdomen</subject><subject>Biological and medical sciences</subject><subject>Drug Administration Schedule</subject><subject>Drug Combinations</subject><subject>Female</subject><subject>Helicobacter Infections - drug therapy</subject><subject>Helicobacter pylori</subject><subject>Human bacterial diseases</subject><subject>Humans</subject><subject>Infectious diseases</subject><subject>Iran</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pharmacology. Drug treatments</subject><subject>therapeutics</subject><subject>Treatment Outcome</subject><subject>Tropical medicine</subject><issn>0815-9319</issn><issn>1440-1746</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><recordid>eNqNkE1v0zAYgC0EYmXwF5AvcEv2-iuODxzQBO2mAkKAOCHLcd6AS5pkdqq2_55krbYrp9eyn8e2HkIog5yBLK42OZMSMqZlkXMAkQMvjc4PT8ji4eApWUDJVGYEMxfkRUobAJCg1XNywbhihrNyQX6t-z1dYRt8Xzk_YqTDse1joBhdHbwbQ9_R6EZMdB_GP1Rm1HU11VntjjTi77DFLtHQTbv0JrouTHPoh117b74kzxrXJnx1npfkx8cP369X2frL8ub6_TrzslQ6874sXeMrqJQUvBCGg-HSFzVKbCoBCkypFTppBDqlauUYeqhVWXsvOWfikrw93TvE_m6HabTbkDy2reuw3yWruZHcgJ7A8gT62KcUsbFDDFsXj5aBndPajZ0L2rmgndPa-7T2MKmvz2_sqi3Wj-K55QS8OQMuedc2Uw0f0iMnFQcuZu7diduHFo___QF7u1zNq8nPTn5IIx4efBf_2kILrezPz0v76dvqK-jC2LX4BzOzoxA</recordid><startdate>200301</startdate><enddate>200301</enddate><creator>MALEKZADEH, REZA</creator><creator>MERAT, SHAHIN</creator><creator>DERAKHSHAN, MOHAMMAD-HASSAN</creator><creator>SIAVOSHI, FARIDEH</creator><creator>YAZDANBOD, ABBAS</creator><creator>MIKAELI, JAVAD</creator><creator>SOTOUDEMANESH, RASOUL</creator><creator>SOTOUDEH, MASOUD</creator><creator>FARAHVASH, MOHAMMAD-JAFAR</creator><creator>NASSERI-MOGHADDAM, SIAVOSH</creator><creator>POURSHAMS, AKRAM</creator><creator>DOLATSHAHI, SHAHAB</creator><creator>ABEDI, BEHNOOSH</creator><creator>BABAEI, MASOUD</creator><creator>ARSHI, SHAHNAM</creator><creator>MAJIDPOUR, ALI</creator><general>Blackwell Science Pty</general><general>Blackwell Science</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200301</creationdate><title>Low Helicobacter pylori eradication rates with 4- and 7-day regimens in an Iranian population</title><author>MALEKZADEH, REZA ; MERAT, SHAHIN ; DERAKHSHAN, MOHAMMAD-HASSAN ; SIAVOSHI, FARIDEH ; YAZDANBOD, ABBAS ; MIKAELI, JAVAD ; SOTOUDEMANESH, RASOUL ; SOTOUDEH, MASOUD ; FARAHVASH, MOHAMMAD-JAFAR ; NASSERI-MOGHADDAM, SIAVOSH ; POURSHAMS, AKRAM ; DOLATSHAHI, SHAHAB ; ABEDI, BEHNOOSH ; BABAEI, MASOUD ; ARSHI, SHAHNAM ; MAJIDPOUR, ALI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4857-cc88afcb0b543263920924c6de4efb30509875ea493ea55d5a1ec0d58dcc42213</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Aged</topic><topic>Anti-Bacterial Agents - administration & dosage</topic><topic>Antibacterial agents</topic><topic>Antibiotics. Antiinfectious agents. Antiparasitic agents</topic><topic>Bacterial diseases</topic><topic>Bacterial diseases of the digestive system and abdomen</topic><topic>Biological and medical sciences</topic><topic>Drug Administration Schedule</topic><topic>Drug Combinations</topic><topic>Female</topic><topic>Helicobacter Infections - drug therapy</topic><topic>Helicobacter pylori</topic><topic>Human bacterial diseases</topic><topic>Humans</topic><topic>Infectious diseases</topic><topic>Iran</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Pharmacology. Drug treatments</topic><topic>therapeutics</topic><topic>Treatment Outcome</topic><topic>Tropical medicine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>MALEKZADEH, REZA</creatorcontrib><creatorcontrib>MERAT, SHAHIN</creatorcontrib><creatorcontrib>DERAKHSHAN, MOHAMMAD-HASSAN</creatorcontrib><creatorcontrib>SIAVOSHI, FARIDEH</creatorcontrib><creatorcontrib>YAZDANBOD, ABBAS</creatorcontrib><creatorcontrib>MIKAELI, JAVAD</creatorcontrib><creatorcontrib>SOTOUDEMANESH, RASOUL</creatorcontrib><creatorcontrib>SOTOUDEH, MASOUD</creatorcontrib><creatorcontrib>FARAHVASH, MOHAMMAD-JAFAR</creatorcontrib><creatorcontrib>NASSERI-MOGHADDAM, SIAVOSH</creatorcontrib><creatorcontrib>POURSHAMS, AKRAM</creatorcontrib><creatorcontrib>DOLATSHAHI, SHAHAB</creatorcontrib><creatorcontrib>ABEDI, BEHNOOSH</creatorcontrib><creatorcontrib>BABAEI, MASOUD</creatorcontrib><creatorcontrib>ARSHI, SHAHNAM</creatorcontrib><creatorcontrib>MAJIDPOUR, ALI</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of gastroenterology and hepatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>MALEKZADEH, REZA</au><au>MERAT, SHAHIN</au><au>DERAKHSHAN, MOHAMMAD-HASSAN</au><au>SIAVOSHI, FARIDEH</au><au>YAZDANBOD, ABBAS</au><au>MIKAELI, JAVAD</au><au>SOTOUDEMANESH, RASOUL</au><au>SOTOUDEH, MASOUD</au><au>FARAHVASH, MOHAMMAD-JAFAR</au><au>NASSERI-MOGHADDAM, SIAVOSH</au><au>POURSHAMS, AKRAM</au><au>DOLATSHAHI, SHAHAB</au><au>ABEDI, BEHNOOSH</au><au>BABAEI, MASOUD</au><au>ARSHI, SHAHNAM</au><au>MAJIDPOUR, ALI</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Low Helicobacter pylori eradication rates with 4- and 7-day regimens in an Iranian population</atitle><jtitle>Journal of gastroenterology and hepatology</jtitle><addtitle>J Gastroenterol Hepatol</addtitle><date>2003-01</date><risdate>2003</risdate><volume>18</volume><issue>1</issue><spage>13</spage><epage>17</epage><pages>13-17</pages><issn>0815-9319</issn><eissn>1440-1746</eissn><notes>istex:8FE26934D50A65B5AF1B3C1DD354663E417EFA2C</notes><notes>ArticleID:JGH2897</notes><notes>ark:/67375/WNG-MSHQ0769-L</notes><notes>ObjectType-Article-2</notes><notes>SourceType-Scholarly Journals-1</notes><notes>ObjectType-Feature-1</notes><notes>ObjectType-News-3</notes><notes>content type line 23</notes><abstract>Background: In Iran, there is insufficient information on the efficacy of Helicobacter pylori eradication regimens shorter than 10 days. This study aims at assessing the efficacy of 4‐ and 7‐day H. pylori eradication regimens in a high‐incidence area of gastric cancer in Iran.
Methods: Subjects with an endoscopic diagnosis of gastritis, positive urease test, and a histological diagnosis of chronic gastritis were enrolled. Patients were randomly assigned to one of three groups: AOC7 (1000 mg amoxicillin, 20 mg omeprazole, and 500 mg clarithromycin twice daily for 7 days), FOT4 (200 mg furazolidone, 20 mg omeprazole, and 500 mg tetracycline twice daily for 4 days) and FOT7 (the same treatment as the FOT4 group but for 7 days). Sensitivity to these antibiotics was determined in all isolates recovered from culture. The efficacy of eradication was assessed 8 weeks after the end‐of‐treatment by the 14C‐urea breath test.
Results: One hundred and twenty‐eight patients were enrolled in the study. Culture was positive for 84 patients and none of these were resistant to amoxicillin, tetracycline or furazolidone, 1.2% were resistant to clarithromycin and 32.1% to metronidazole. Forty‐five, 41 and 42 patients were randomly allocated to the AOC7, FOT4, and FOT7 groups, respectively. The intention‐to‐treat eradication rates were 35.5, 17.1, and 23.8% for the AOC7, FOT4, and FOT7 groups, respectively.
Conclusion: Treatment regimens of 4 or 7 days are unacceptable for H. pylori infection in Iran, even in the presence of a favorable sensitivity profile.
© 2003 Blackwell Publishing Asia Pty Ltd</abstract><cop>Melbourne, Australia</cop><pub>Blackwell Science Pty</pub><pmid>12519218</pmid><doi>10.1046/j.1440-1746.2003.02897.x</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Journal of gastroenterology and hepatology, 2003-01, Vol.18 (1), p.13-17 |
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| subjects | Aged Anti-Bacterial Agents - administration & dosage Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Bacterial diseases Bacterial diseases of the digestive system and abdomen Biological and medical sciences Drug Administration Schedule Drug Combinations Female Helicobacter Infections - drug therapy Helicobacter pylori Human bacterial diseases Humans Infectious diseases Iran Male Medical sciences Middle Aged Pharmacology. Drug treatments therapeutics Treatment Outcome Tropical medicine |
| title | Low Helicobacter pylori eradication rates with 4- and 7-day regimens in an Iranian population |
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