Loading…
Therapeutic effects of oral nutritional supplementation during hemodialysis
Therapeutic effects of oral nutritional supplementation during hemodialysis. Protein-calorie malnutrition is common in chronic hemodialysis (CHD) patients and correlates with morbidity and mortality in these patients. There are limited trials evaluating the efficacy of oral nutritional supplementati...
Saved in:
| Published in: | Kidney international 2002-09, Vol.62 (3), p.1054-1059 |
|---|---|
| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c565t-c34b267ce31c27731dbfc251d2d420a614710eb7be50385443f2544952cc36883 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c565t-c34b267ce31c27731dbfc251d2d420a614710eb7be50385443f2544952cc36883 |
| container_end_page | 1059 |
| container_issue | 3 |
| container_start_page | 1054 |
| container_title | Kidney international |
| container_volume | 62 |
| creator | Caglar, Kayser Fedje, Lori Dimmitt, Rita Hakim, Raymond M. Shyr, Yu Ikizler, T. Alp |
| description | Therapeutic effects of oral nutritional supplementation during hemodialysis.
Protein-calorie malnutrition is common in chronic hemodialysis (CHD) patients and correlates with morbidity and mortality in these patients. There are limited trials evaluating the efficacy of oral nutritional supplementation in malnourished CHD patients.
Eighty-five CHD patients with evidence of malnutrition were included in this prospective study. Patients were followed for a 3-month baseline period during which they received conventional nutrition counseling. This was followed by an intervention period, during which an oral nutritional supplement specifically formulated for CHD patients was given over a period of 6 months. An important element of this study was that the nutritional supplement was provided during dialysis to ensure compliance. Serial measurements of nutritional parameters including concentrations of serum albumin, prealbumin, transferrin as well as body mass index (BMI) and subjective global assessment (SGA) were obtained during the 9-month period.
The nutritional parameters did not change during the 3-month baseline period. Following administration of oral supplementation during hemodialysis, there were significant increases in concentrations of serum albumin (from 3.33 ± 0.32 g/dL at baseline, to 3.65 ± 0.26 g/dL at month 6, P < 0.0001) and serum prealbumin (from 26.1 ± 8.6 mg/dL at baseline, to 30.7 ± 7.4 mg/dL at month 6, P = 0.002). Mean SGA score increased 14% by the end of the study (P = 0.023). Although BMI and estimated dry weight increased also, these changes were not statistically significant. Serum transferrin did not change during the study period.
Oral nutritional supplementation given during hemodialysis improves nutritional markers in malnourished CHD patients. |
| doi_str_mv | 10.1046/j.1523-1755.2002.00530.x |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_72000021</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0085253815486430</els_id><sourcerecordid>72000021</sourcerecordid><originalsourceid>FETCH-LOGICAL-c565t-c34b267ce31c27731dbfc251d2d420a614710eb7be50385443f2544952cc36883</originalsourceid><addsrcrecordid>eNqFkctu1TAQQC0EoreFTwBFSGWXdPxKnCVUpSAqdVPWluNMqK-SONgxav8eh3vVSmzY-DVnRjPHhBQUKgqivthXVDJe0kbKigGwCkByqB5ekN1T4CXZAShZMsnVCTmNcQ_53nJ4TU4oo7VQLezI97t7DGbBtDpb4DCgXWPhh8IHMxZzWoNbnZ_zOaZlGXHCeTXbS9Gn4OafxT1OvndmfIwuviGvBjNGfHvcz8iPL1d3l1_Lm9vrb5efbkora7mWlouO1Y1FTi1rGk77brBM0p71goGpqWgoYNd0KIErKQQfWF5byazltVL8jHw81F2C_5Uwrnpy0eI4mhl9irrJSrIUmsEP_4B7n0KeJmpGgbIGmjpD6gDZ4GMMOOgluMmER01Bb7b1Xm9S9SZVb7b1X9v6Iae-P9ZP3YT9c-JRbwbOj4CJ1oxDMLN18ZnjSrSqFpl7d-Bms6aAT0CemtN26_HzIY5Z62-HQUfrcLbYu5B_TPfe_b_bP1L4prY</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>210127076</pqid></control><display><type>article</type><title>Therapeutic effects of oral nutritional supplementation during hemodialysis</title><source>BACON - Elsevier - GLOBAL_SCIENCEDIRECT-OPENACCESS</source><creator>Caglar, Kayser ; Fedje, Lori ; Dimmitt, Rita ; Hakim, Raymond M. ; Shyr, Yu ; Ikizler, T. Alp</creator><creatorcontrib>Caglar, Kayser ; Fedje, Lori ; Dimmitt, Rita ; Hakim, Raymond M. ; Shyr, Yu ; Ikizler, T. Alp</creatorcontrib><description>Therapeutic effects of oral nutritional supplementation during hemodialysis.
Protein-calorie malnutrition is common in chronic hemodialysis (CHD) patients and correlates with morbidity and mortality in these patients. There are limited trials evaluating the efficacy of oral nutritional supplementation in malnourished CHD patients.
Eighty-five CHD patients with evidence of malnutrition were included in this prospective study. Patients were followed for a 3-month baseline period during which they received conventional nutrition counseling. This was followed by an intervention period, during which an oral nutritional supplement specifically formulated for CHD patients was given over a period of 6 months. An important element of this study was that the nutritional supplement was provided during dialysis to ensure compliance. Serial measurements of nutritional parameters including concentrations of serum albumin, prealbumin, transferrin as well as body mass index (BMI) and subjective global assessment (SGA) were obtained during the 9-month period.
The nutritional parameters did not change during the 3-month baseline period. Following administration of oral supplementation during hemodialysis, there were significant increases in concentrations of serum albumin (from 3.33 ± 0.32 g/dL at baseline, to 3.65 ± 0.26 g/dL at month 6, P < 0.0001) and serum prealbumin (from 26.1 ± 8.6 mg/dL at baseline, to 30.7 ± 7.4 mg/dL at month 6, P = 0.002). Mean SGA score increased 14% by the end of the study (P = 0.023). Although BMI and estimated dry weight increased also, these changes were not statistically significant. Serum transferrin did not change during the study period.
Oral nutritional supplementation given during hemodialysis improves nutritional markers in malnourished CHD patients.</description><identifier>ISSN: 0085-2538</identifier><identifier>EISSN: 1523-1755</identifier><identifier>DOI: 10.1046/j.1523-1755.2002.00530.x</identifier><identifier>PMID: 12164890</identifier><identifier>CODEN: KDYIA5</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Biological and medical sciences ; chronic hemodialysis ; diet ESRD ; Dietary Supplements ; Emergency and intensive care: renal failure. Dialysis management ; Female ; Humans ; Intensive care medicine ; Kidney Failure, Chronic - complications ; Kidney Failure, Chronic - therapy ; Male ; Medical sciences ; Middle Aged ; Prospective Studies ; protein calorie malnutrition ; Protein-Energy Malnutrition - diet therapy ; Protein-Energy Malnutrition - etiology ; Renal Dialysis ; Serum Albumin ; serum prealbumin ; subjective global assessment</subject><ispartof>Kidney international, 2002-09, Vol.62 (3), p.1054-1059</ispartof><rights>2002 International Society of Nephrology</rights><rights>2002 INIST-CNRS</rights><rights>Copyright Nature Publishing Group Sep 2002</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c565t-c34b267ce31c27731dbfc251d2d420a614710eb7be50385443f2544952cc36883</citedby><cites>FETCH-LOGICAL-c565t-c34b267ce31c27731dbfc251d2d420a614710eb7be50385443f2544952cc36883</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,786,790,27957,27958</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=13849864$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12164890$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Caglar, Kayser</creatorcontrib><creatorcontrib>Fedje, Lori</creatorcontrib><creatorcontrib>Dimmitt, Rita</creatorcontrib><creatorcontrib>Hakim, Raymond M.</creatorcontrib><creatorcontrib>Shyr, Yu</creatorcontrib><creatorcontrib>Ikizler, T. Alp</creatorcontrib><title>Therapeutic effects of oral nutritional supplementation during hemodialysis</title><title>Kidney international</title><addtitle>Kidney Int</addtitle><description>Therapeutic effects of oral nutritional supplementation during hemodialysis.
Protein-calorie malnutrition is common in chronic hemodialysis (CHD) patients and correlates with morbidity and mortality in these patients. There are limited trials evaluating the efficacy of oral nutritional supplementation in malnourished CHD patients.
Eighty-five CHD patients with evidence of malnutrition were included in this prospective study. Patients were followed for a 3-month baseline period during which they received conventional nutrition counseling. This was followed by an intervention period, during which an oral nutritional supplement specifically formulated for CHD patients was given over a period of 6 months. An important element of this study was that the nutritional supplement was provided during dialysis to ensure compliance. Serial measurements of nutritional parameters including concentrations of serum albumin, prealbumin, transferrin as well as body mass index (BMI) and subjective global assessment (SGA) were obtained during the 9-month period.
The nutritional parameters did not change during the 3-month baseline period. Following administration of oral supplementation during hemodialysis, there were significant increases in concentrations of serum albumin (from 3.33 ± 0.32 g/dL at baseline, to 3.65 ± 0.26 g/dL at month 6, P < 0.0001) and serum prealbumin (from 26.1 ± 8.6 mg/dL at baseline, to 30.7 ± 7.4 mg/dL at month 6, P = 0.002). Mean SGA score increased 14% by the end of the study (P = 0.023). Although BMI and estimated dry weight increased also, these changes were not statistically significant. Serum transferrin did not change during the study period.
Oral nutritional supplementation given during hemodialysis improves nutritional markers in malnourished CHD patients.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>chronic hemodialysis</subject><subject>diet ESRD</subject><subject>Dietary Supplements</subject><subject>Emergency and intensive care: renal failure. Dialysis management</subject><subject>Female</subject><subject>Humans</subject><subject>Intensive care medicine</subject><subject>Kidney Failure, Chronic - complications</subject><subject>Kidney Failure, Chronic - therapy</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Prospective Studies</subject><subject>protein calorie malnutrition</subject><subject>Protein-Energy Malnutrition - diet therapy</subject><subject>Protein-Energy Malnutrition - etiology</subject><subject>Renal Dialysis</subject><subject>Serum Albumin</subject><subject>serum prealbumin</subject><subject>subjective global assessment</subject><issn>0085-2538</issn><issn>1523-1755</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><recordid>eNqFkctu1TAQQC0EoreFTwBFSGWXdPxKnCVUpSAqdVPWluNMqK-SONgxav8eh3vVSmzY-DVnRjPHhBQUKgqivthXVDJe0kbKigGwCkByqB5ekN1T4CXZAShZMsnVCTmNcQ_53nJ4TU4oo7VQLezI97t7DGbBtDpb4DCgXWPhh8IHMxZzWoNbnZ_zOaZlGXHCeTXbS9Gn4OafxT1OvndmfIwuviGvBjNGfHvcz8iPL1d3l1_Lm9vrb5efbkora7mWlouO1Y1FTi1rGk77brBM0p71goGpqWgoYNd0KIErKQQfWF5byazltVL8jHw81F2C_5Uwrnpy0eI4mhl9irrJSrIUmsEP_4B7n0KeJmpGgbIGmjpD6gDZ4GMMOOgluMmER01Bb7b1Xm9S9SZVb7b1X9v6Iae-P9ZP3YT9c-JRbwbOj4CJ1oxDMLN18ZnjSrSqFpl7d-Bms6aAT0CemtN26_HzIY5Z62-HQUfrcLbYu5B_TPfe_b_bP1L4prY</recordid><startdate>20020901</startdate><enddate>20020901</enddate><creator>Caglar, Kayser</creator><creator>Fedje, Lori</creator><creator>Dimmitt, Rita</creator><creator>Hakim, Raymond M.</creator><creator>Shyr, Yu</creator><creator>Ikizler, T. Alp</creator><general>Elsevier Inc</general><general>Nature Publishing</general><general>Elsevier Limited</general><scope>6I.</scope><scope>AAFTH</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20020901</creationdate><title>Therapeutic effects of oral nutritional supplementation during hemodialysis</title><author>Caglar, Kayser ; Fedje, Lori ; Dimmitt, Rita ; Hakim, Raymond M. ; Shyr, Yu ; Ikizler, T. Alp</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c565t-c34b267ce31c27731dbfc251d2d420a614710eb7be50385443f2544952cc36883</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Biological and medical sciences</topic><topic>chronic hemodialysis</topic><topic>diet ESRD</topic><topic>Dietary Supplements</topic><topic>Emergency and intensive care: renal failure. Dialysis management</topic><topic>Female</topic><topic>Humans</topic><topic>Intensive care medicine</topic><topic>Kidney Failure, Chronic - complications</topic><topic>Kidney Failure, Chronic - therapy</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Prospective Studies</topic><topic>protein calorie malnutrition</topic><topic>Protein-Energy Malnutrition - diet therapy</topic><topic>Protein-Energy Malnutrition - etiology</topic><topic>Renal Dialysis</topic><topic>Serum Albumin</topic><topic>serum prealbumin</topic><topic>subjective global assessment</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Caglar, Kayser</creatorcontrib><creatorcontrib>Fedje, Lori</creatorcontrib><creatorcontrib>Dimmitt, Rita</creatorcontrib><creatorcontrib>Hakim, Raymond M.</creatorcontrib><creatorcontrib>Shyr, Yu</creatorcontrib><creatorcontrib>Ikizler, T. Alp</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Proquest Nursing & Allied Health Source</collection><collection>Proquest Health & Medical Complete</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Kidney international</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Caglar, Kayser</au><au>Fedje, Lori</au><au>Dimmitt, Rita</au><au>Hakim, Raymond M.</au><au>Shyr, Yu</au><au>Ikizler, T. Alp</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Therapeutic effects of oral nutritional supplementation during hemodialysis</atitle><jtitle>Kidney international</jtitle><addtitle>Kidney Int</addtitle><date>2002-09-01</date><risdate>2002</risdate><volume>62</volume><issue>3</issue><spage>1054</spage><epage>1059</epage><pages>1054-1059</pages><issn>0085-2538</issn><eissn>1523-1755</eissn><coden>KDYIA5</coden><notes>ObjectType-Article-2</notes><notes>SourceType-Scholarly Journals-1</notes><notes>ObjectType-Feature-1</notes><notes>content type line 23</notes><abstract>Therapeutic effects of oral nutritional supplementation during hemodialysis.
Protein-calorie malnutrition is common in chronic hemodialysis (CHD) patients and correlates with morbidity and mortality in these patients. There are limited trials evaluating the efficacy of oral nutritional supplementation in malnourished CHD patients.
Eighty-five CHD patients with evidence of malnutrition were included in this prospective study. Patients were followed for a 3-month baseline period during which they received conventional nutrition counseling. This was followed by an intervention period, during which an oral nutritional supplement specifically formulated for CHD patients was given over a period of 6 months. An important element of this study was that the nutritional supplement was provided during dialysis to ensure compliance. Serial measurements of nutritional parameters including concentrations of serum albumin, prealbumin, transferrin as well as body mass index (BMI) and subjective global assessment (SGA) were obtained during the 9-month period.
The nutritional parameters did not change during the 3-month baseline period. Following administration of oral supplementation during hemodialysis, there were significant increases in concentrations of serum albumin (from 3.33 ± 0.32 g/dL at baseline, to 3.65 ± 0.26 g/dL at month 6, P < 0.0001) and serum prealbumin (from 26.1 ± 8.6 mg/dL at baseline, to 30.7 ± 7.4 mg/dL at month 6, P = 0.002). Mean SGA score increased 14% by the end of the study (P = 0.023). Although BMI and estimated dry weight increased also, these changes were not statistically significant. Serum transferrin did not change during the study period.
Oral nutritional supplementation given during hemodialysis improves nutritional markers in malnourished CHD patients.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>12164890</pmid><doi>10.1046/j.1523-1755.2002.00530.x</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0085-2538 |
| ispartof | Kidney international, 2002-09, Vol.62 (3), p.1054-1059 |
| issn | 0085-2538 1523-1755 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_72000021 |
| source | BACON - Elsevier - GLOBAL_SCIENCEDIRECT-OPENACCESS |
| subjects | Adult Aged Aged, 80 and over Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences chronic hemodialysis diet ESRD Dietary Supplements Emergency and intensive care: renal failure. Dialysis management Female Humans Intensive care medicine Kidney Failure, Chronic - complications Kidney Failure, Chronic - therapy Male Medical sciences Middle Aged Prospective Studies protein calorie malnutrition Protein-Energy Malnutrition - diet therapy Protein-Energy Malnutrition - etiology Renal Dialysis Serum Albumin serum prealbumin subjective global assessment |
| title | Therapeutic effects of oral nutritional supplementation during hemodialysis |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-09-23T05%3A21%3A15IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Therapeutic%20effects%20of%20oral%20nutritional%20supplementation%20during%20hemodialysis&rft.jtitle=Kidney%20international&rft.au=Caglar,%20Kayser&rft.date=2002-09-01&rft.volume=62&rft.issue=3&rft.spage=1054&rft.epage=1059&rft.pages=1054-1059&rft.issn=0085-2538&rft.eissn=1523-1755&rft.coden=KDYIA5&rft_id=info:doi/10.1046/j.1523-1755.2002.00530.x&rft_dat=%3Cproquest_cross%3E72000021%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c565t-c34b267ce31c27731dbfc251d2d420a614710eb7be50385443f2544952cc36883%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=210127076&rft_id=info:pmid/12164890&rfr_iscdi=true |