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Perinatal outcomes after successful and failed trials of labor after cesarean delivery

Objective To compare maternal and neonatal outcomes after successful and failed trials of labor after cesarean in women at term, excluding uterine ruptures, and to examine predictors of successful and failed trials of labor. Study Design Matched maternal and neonatal data from 1993-1999 in women wit...

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Published in:American journal of obstetrics and gynecology 2007-06, Vol.196 (6), p.583.e1-583.e5
Main Authors: El-Sayed, Yasser Y., MD, Watkins, Melanie M., MD, Fix, Megan, MD, Druzin, Maurice L., MD, Pullen, Kristin M., MD, Caughey, Aaron B., MD, PhD
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container_title American journal of obstetrics and gynecology
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description Objective To compare maternal and neonatal outcomes after successful and failed trials of labor after cesarean in women at term, excluding uterine ruptures, and to examine predictors of successful and failed trials of labor. Study Design Matched maternal and neonatal data from 1993-1999 in women with singleton term pregnancies with prior cesarean undergoing trial of labor were reviewed. Women with uterine rupture were excluded. Maternal and neonatal outcomes were analyzed for successful and failed trials. Predictors of success and failure were examined. Results 1284 women and their neonates were available for analysis. 1094 (85.2%) had a vaginal birth and 190 (14.8%) underwent repeat cesarean. Failed trials of labor were associated with higher incidence of choriamnionitis (25.8% vs. 5.5%, P
doi_str_mv 10.1016/j.ajog.2007.03.013
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Study Design Matched maternal and neonatal data from 1993-1999 in women with singleton term pregnancies with prior cesarean undergoing trial of labor were reviewed. Women with uterine rupture were excluded. Maternal and neonatal outcomes were analyzed for successful and failed trials. Predictors of success and failure were examined. Results 1284 women and their neonates were available for analysis. 1094 (85.2%) had a vaginal birth and 190 (14.8%) underwent repeat cesarean. Failed trials of labor were associated with higher incidence of choriamnionitis (25.8% vs. 5.5%, P &lt;.001), postpartum hemorrhage (35.8% vs. 15.8%, P &lt;.001), hysterectomy (1% vs. 0%, P =.022), neonatal jaundice (17.4% vs.10.2%, P =.004) and composite major neonatal morbidities (6.3% vs. 2.8%, P =.014). Conclusion Failed trial of labor in women at term with prior cesarean is associated with increased maternal and neonatal morbidities.</description><identifier>ISSN: 0002-9378</identifier><identifier>EISSN: 1097-6868</identifier><identifier>DOI: 10.1016/j.ajog.2007.03.013</identifier><identifier>PMID: 17547905</identifier><language>eng</language><publisher>United States: Mosby, Inc</publisher><subject>Acidosis - epidemiology ; Adult ; Anesthesia, Epidural ; Anesthesia, Obstetrical ; Birth Injuries - epidemiology ; Birth Weight ; California - epidemiology ; Cerebral Hemorrhage - epidemiology ; Cesarean Section - statistics &amp; numerical data ; Chorioamnionitis - epidemiology ; Cohort Studies ; Continental Population Groups ; Female ; Humans ; Hysterectomy - statistics &amp; numerical data ; Infant, Newborn ; Jaundice, Neonatal - epidemiology ; Multivariate Analysis ; Obstetrics and Gynecology ; perinatal outcomes ; Pneumonia - epidemiology ; Postpartum Hemorrhage - epidemiology ; Pregnancy ; Respiratory Distress Syndrome, Newborn - epidemiology ; Retrospective Studies ; Sepsis - epidemiology ; Trial of Labor ; Umbilical Cord - chemistry ; Vaginal Birth after Cesarean - statistics &amp; numerical data ; VBAC</subject><ispartof>American journal of obstetrics and gynecology, 2007-06, Vol.196 (6), p.583.e1-583.e5</ispartof><rights>Mosby, Inc.</rights><rights>2007 Mosby, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c409t-9f92274aba8553cb64e66dc6c0278904b9b84c3feba6682f79bf08a3efe38c013</citedby><cites>FETCH-LOGICAL-c409t-9f92274aba8553cb64e66dc6c0278904b9b84c3feba6682f79bf08a3efe38c013</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,786,790,27957,27958</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17547905$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>El-Sayed, Yasser Y., MD</creatorcontrib><creatorcontrib>Watkins, Melanie M., MD</creatorcontrib><creatorcontrib>Fix, Megan, MD</creatorcontrib><creatorcontrib>Druzin, Maurice L., MD</creatorcontrib><creatorcontrib>Pullen, Kristin M., MD</creatorcontrib><creatorcontrib>Caughey, Aaron B., MD, PhD</creatorcontrib><title>Perinatal outcomes after successful and failed trials of labor after cesarean delivery</title><title>American journal of obstetrics and gynecology</title><addtitle>Am J Obstet Gynecol</addtitle><description>Objective To compare maternal and neonatal outcomes after successful and failed trials of labor after cesarean in women at term, excluding uterine ruptures, and to examine predictors of successful and failed trials of labor. Study Design Matched maternal and neonatal data from 1993-1999 in women with singleton term pregnancies with prior cesarean undergoing trial of labor were reviewed. Women with uterine rupture were excluded. Maternal and neonatal outcomes were analyzed for successful and failed trials. Predictors of success and failure were examined. Results 1284 women and their neonates were available for analysis. 1094 (85.2%) had a vaginal birth and 190 (14.8%) underwent repeat cesarean. Failed trials of labor were associated with higher incidence of choriamnionitis (25.8% vs. 5.5%, P &lt;.001), postpartum hemorrhage (35.8% vs. 15.8%, P &lt;.001), hysterectomy (1% vs. 0%, P =.022), neonatal jaundice (17.4% vs.10.2%, P =.004) and composite major neonatal morbidities (6.3% vs. 2.8%, P =.014). Conclusion Failed trial of labor in women at term with prior cesarean is associated with increased maternal and neonatal morbidities.</description><subject>Acidosis - epidemiology</subject><subject>Adult</subject><subject>Anesthesia, Epidural</subject><subject>Anesthesia, Obstetrical</subject><subject>Birth Injuries - epidemiology</subject><subject>Birth Weight</subject><subject>California - epidemiology</subject><subject>Cerebral Hemorrhage - epidemiology</subject><subject>Cesarean Section - statistics &amp; numerical data</subject><subject>Chorioamnionitis - epidemiology</subject><subject>Cohort Studies</subject><subject>Continental Population Groups</subject><subject>Female</subject><subject>Humans</subject><subject>Hysterectomy - statistics &amp; numerical data</subject><subject>Infant, Newborn</subject><subject>Jaundice, Neonatal - epidemiology</subject><subject>Multivariate Analysis</subject><subject>Obstetrics and Gynecology</subject><subject>perinatal outcomes</subject><subject>Pneumonia - epidemiology</subject><subject>Postpartum Hemorrhage - epidemiology</subject><subject>Pregnancy</subject><subject>Respiratory Distress Syndrome, Newborn - epidemiology</subject><subject>Retrospective Studies</subject><subject>Sepsis - epidemiology</subject><subject>Trial of Labor</subject><subject>Umbilical Cord - chemistry</subject><subject>Vaginal Birth after Cesarean - statistics &amp; numerical data</subject><subject>VBAC</subject><issn>0002-9378</issn><issn>1097-6868</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><recordid>eNp9kV2L1TAQhoMo7nH1D3ghufKudZK0-QARZPELFhT8uA1pOpHUnGZN2oXz7205BwQvvBoGnveFeYaQ5wxaBky-mlo35Z8tB1AtiBaYeEAODIxqpJb6ITkAAG-MUPqKPKl12ldu-GNyxVTfKQP9gfz4giXObnGJ5nXx-YiVurBgoXX1HmsNa6JuHmlwMeFIlxJdqjQHmtyQy4XdQFfQzXTEFO-xnJ6SR2Hj8NllXpPv7999u_nY3H7-8Onm7W3jOzBLY4LhXHVucLrvhR9kh1KOXnrgShvoBjPozouAg5NS86DMEEA7gQGF9tvB1-Tlufeu5N8r1sUeY_WYkpsxr9Uq6KWSIDeQn0Ffcq0Fg70r8ejKyTKwu0072d2m3W1aEHYr30IvLu3rcMTxb-SibwNenwHcbryPWGz1EWePYyzoFzvm-P_-N__EfYpz9C79whPWKa9l3uxZZiu3YL_uD9zfCQpAgGDiDwULm6Y</recordid><startdate>20070601</startdate><enddate>20070601</enddate><creator>El-Sayed, Yasser Y., MD</creator><creator>Watkins, Melanie M., MD</creator><creator>Fix, Megan, MD</creator><creator>Druzin, Maurice L., MD</creator><creator>Pullen, Kristin M., MD</creator><creator>Caughey, Aaron B., MD, PhD</creator><general>Mosby, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20070601</creationdate><title>Perinatal outcomes after successful and failed trials of labor after cesarean delivery</title><author>El-Sayed, Yasser Y., MD ; Watkins, Melanie M., MD ; Fix, Megan, MD ; Druzin, Maurice L., MD ; Pullen, Kristin M., MD ; Caughey, Aaron B., MD, PhD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c409t-9f92274aba8553cb64e66dc6c0278904b9b84c3feba6682f79bf08a3efe38c013</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Acidosis - epidemiology</topic><topic>Adult</topic><topic>Anesthesia, Epidural</topic><topic>Anesthesia, Obstetrical</topic><topic>Birth Injuries - epidemiology</topic><topic>Birth Weight</topic><topic>California - epidemiology</topic><topic>Cerebral Hemorrhage - epidemiology</topic><topic>Cesarean Section - statistics &amp; numerical data</topic><topic>Chorioamnionitis - epidemiology</topic><topic>Cohort Studies</topic><topic>Continental Population Groups</topic><topic>Female</topic><topic>Humans</topic><topic>Hysterectomy - statistics &amp; numerical data</topic><topic>Infant, Newborn</topic><topic>Jaundice, Neonatal - epidemiology</topic><topic>Multivariate Analysis</topic><topic>Obstetrics and Gynecology</topic><topic>perinatal outcomes</topic><topic>Pneumonia - epidemiology</topic><topic>Postpartum Hemorrhage - epidemiology</topic><topic>Pregnancy</topic><topic>Respiratory Distress Syndrome, Newborn - epidemiology</topic><topic>Retrospective Studies</topic><topic>Sepsis - epidemiology</topic><topic>Trial of Labor</topic><topic>Umbilical Cord - chemistry</topic><topic>Vaginal Birth after Cesarean - statistics &amp; numerical data</topic><topic>VBAC</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>El-Sayed, Yasser Y., MD</creatorcontrib><creatorcontrib>Watkins, Melanie M., MD</creatorcontrib><creatorcontrib>Fix, Megan, MD</creatorcontrib><creatorcontrib>Druzin, Maurice L., MD</creatorcontrib><creatorcontrib>Pullen, Kristin M., MD</creatorcontrib><creatorcontrib>Caughey, Aaron B., MD, PhD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of obstetrics and gynecology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>El-Sayed, Yasser Y., MD</au><au>Watkins, Melanie M., MD</au><au>Fix, Megan, MD</au><au>Druzin, Maurice L., MD</au><au>Pullen, Kristin M., MD</au><au>Caughey, Aaron B., MD, PhD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Perinatal outcomes after successful and failed trials of labor after cesarean delivery</atitle><jtitle>American journal of obstetrics and gynecology</jtitle><addtitle>Am J Obstet Gynecol</addtitle><date>2007-06-01</date><risdate>2007</risdate><volume>196</volume><issue>6</issue><spage>583.e1</spage><epage>583.e5</epage><pages>583.e1-583.e5</pages><issn>0002-9378</issn><eissn>1097-6868</eissn><notes>ObjectType-Article-1</notes><notes>SourceType-Scholarly Journals-1</notes><notes>ObjectType-Feature-2</notes><notes>content type line 23</notes><abstract>Objective To compare maternal and neonatal outcomes after successful and failed trials of labor after cesarean in women at term, excluding uterine ruptures, and to examine predictors of successful and failed trials of labor. Study Design Matched maternal and neonatal data from 1993-1999 in women with singleton term pregnancies with prior cesarean undergoing trial of labor were reviewed. Women with uterine rupture were excluded. Maternal and neonatal outcomes were analyzed for successful and failed trials. Predictors of success and failure were examined. Results 1284 women and their neonates were available for analysis. 1094 (85.2%) had a vaginal birth and 190 (14.8%) underwent repeat cesarean. Failed trials of labor were associated with higher incidence of choriamnionitis (25.8% vs. 5.5%, P &lt;.001), postpartum hemorrhage (35.8% vs. 15.8%, P &lt;.001), hysterectomy (1% vs. 0%, P =.022), neonatal jaundice (17.4% vs.10.2%, P =.004) and composite major neonatal morbidities (6.3% vs. 2.8%, P =.014). Conclusion Failed trial of labor in women at term with prior cesarean is associated with increased maternal and neonatal morbidities.</abstract><cop>United States</cop><pub>Mosby, Inc</pub><pmid>17547905</pmid><doi>10.1016/j.ajog.2007.03.013</doi></addata></record>
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subjects Acidosis - epidemiology
Adult
Anesthesia, Epidural
Anesthesia, Obstetrical
Birth Injuries - epidemiology
Birth Weight
California - epidemiology
Cerebral Hemorrhage - epidemiology
Cesarean Section - statistics & numerical data
Chorioamnionitis - epidemiology
Cohort Studies
Continental Population Groups
Female
Humans
Hysterectomy - statistics & numerical data
Infant, Newborn
Jaundice, Neonatal - epidemiology
Multivariate Analysis
Obstetrics and Gynecology
perinatal outcomes
Pneumonia - epidemiology
Postpartum Hemorrhage - epidemiology
Pregnancy
Respiratory Distress Syndrome, Newborn - epidemiology
Retrospective Studies
Sepsis - epidemiology
Trial of Labor
Umbilical Cord - chemistry
Vaginal Birth after Cesarean - statistics & numerical data
VBAC
title Perinatal outcomes after successful and failed trials of labor after cesarean delivery
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