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Subband photoacoustic imaging for contrast improvement
Contrast in photoacoustic imaging is primarily determined by optical absorption. This paper proposes a subband imaging method to further enhance the image contrast. The method is based on media with different absorptions generating acoustic waves with different frequency contents. Generally, assumin...
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| Published in: | Optics express 2008-12, Vol.16 (25), p.20215-20226 |
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| Main Authors: | , , |
| Format: | Article |
| Language: | English |
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| cites | cdi_FETCH-LOGICAL-c393t-2f25c0ab9cf2bcff2f512643833334467529a6ada45b34e33a9b8098308d608c3 |
| container_end_page | 20226 |
| container_issue | 25 |
| container_start_page | 20215 |
| container_title | Optics express |
| container_volume | 16 |
| creator | Li, Pai-Chi Wei, Chen-Wei Sheu, Yae-lin |
| description | Contrast in photoacoustic imaging is primarily determined by optical absorption. This paper proposes a subband imaging method to further enhance the image contrast. The method is based on media with different absorptions generating acoustic waves with different frequency contents. Generally, assuming all other conditions remain the same, a high-absorption medium generates acoustic waves with higher frequency components, and hence the imaging contrast can be enhanced by appropriate selection of the spectral subbands. This study employed both finite-difference, time-domain-based simulations and phantom imaging. The numerical results show that the peak frequencies of the signals for objects with absorption coefficients of 1 and 100 cmM(-1) were 2.4 and 7.8 MHz, respectively. Imaging an agar-based phantom further demonstrated that the contrast between two objects with absorption coefficients of 5.01 and 41.75 cm(-1) can be improved by 4-10 dB when the frequency band was changed from 0-7 to 7-14 MHz. Finally, a method to further enhance the contrast based on optimal weighting is also presented. The proposed method is of particular interest in photoacoustic molecular imaging. |
| doi_str_mv | 10.1364/oe.16.020215 |
| format | article |
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This paper proposes a subband imaging method to further enhance the image contrast. The method is based on media with different absorptions generating acoustic waves with different frequency contents. Generally, assuming all other conditions remain the same, a high-absorption medium generates acoustic waves with higher frequency components, and hence the imaging contrast can be enhanced by appropriate selection of the spectral subbands. This study employed both finite-difference, time-domain-based simulations and phantom imaging. The numerical results show that the peak frequencies of the signals for objects with absorption coefficients of 1 and 100 cmM(-1) were 2.4 and 7.8 MHz, respectively. Imaging an agar-based phantom further demonstrated that the contrast between two objects with absorption coefficients of 5.01 and 41.75 cm(-1) can be improved by 4-10 dB when the frequency band was changed from 0-7 to 7-14 MHz. 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| ispartof | Optics express, 2008-12, Vol.16 (25), p.20215-20226 |
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| subjects | Algorithms Elasticity Imaging Techniques - instrumentation Elasticity Imaging Techniques - methods Image Enhancement - methods Image Interpretation, Computer-Assisted - methods Nephelometry and Turbidimetry - instrumentation Nephelometry and Turbidimetry - methods Reproducibility of Results Sensitivity and Specificity |
| title | Subband photoacoustic imaging for contrast improvement |
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