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Biomechanical performance of the new BeadEx implant in the treatment of osteoporotic vertebral body compression fractures: Restoration and maintenance of height and stability
Vertebral compression fractures are counted among the most common complications of osteoporosis. For treatment, a new, alternative implant has been developed (BeadEx, Expandis, Hof HaCarmel, Israel). The aim of the present in vitro study was to evaluate whether this implant is able to restore the in...
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| Published in: | Clinical biomechanics (Bristol) 2006-08, Vol.21 (7), p.676-682 |
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| creator | Kettler, A. Schmoelz, W. Shezifi, Y. Ohana, N. Ben-Arye, A. Claes, L. Wilke, H.-J. |
| description | Vertebral compression fractures are counted among the most common complications of osteoporosis. For treatment, a new, alternative implant has been developed (BeadEx, Expandis, Hof HaCarmel, Israel). The aim of the present in vitro study was to evaluate whether this implant is able to restore the initial height and three-dimensional stability after fracture and whether it is able to maintain this height and stability during complex cyclic loading.
The BeadEx implant consists of small titanium rolls, which are pressed into the vertebral body through specially designed, hollow pedicle screws. The height and the three-dimensional flexibility of 18 bisegmental spine specimens (nine T12–L2, nine L3–L5) was measured, first, before and after creating a wedge compression fracture at the middle vertebral body (L1 resp. L4), second, after treatment of the fracture, and, third, during and after complex cyclic loading. The fractures were treated either with BeadEx plus internal fixator, BeadEx plus bone cement or vertebroplasty for comparison.
The height before fracture could almost be restored by BeadEx plus bone cement but not by BeadEx plus fixator and vertebroplasty. The total height loss after cyclic loading was smallest with BeadEx plus bone cement (in median −4.7
mm with respect to the intact specimens) but −6.2
mm with BeadEx plus fixator and −7.8
mm with vertebroplasty. The three-dimensional stability of the specimens was clearly higher if treated with BeadEx plus fixator than with BeadEx plus bone cement or vertebroplasty.
From a biomechanical point of view, BeadEx plus bone cement can be recommended as an alternative to vertebroplasty in the treatment of osteoporotic vertebral body fractures. BeadEx plus fixator can be recommended if additional stability is needed. |
| doi_str_mv | 10.1016/j.clinbiomech.2006.02.005 |
| format | article |
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The BeadEx implant consists of small titanium rolls, which are pressed into the vertebral body through specially designed, hollow pedicle screws. The height and the three-dimensional flexibility of 18 bisegmental spine specimens (nine T12–L2, nine L3–L5) was measured, first, before and after creating a wedge compression fracture at the middle vertebral body (L1 resp. L4), second, after treatment of the fracture, and, third, during and after complex cyclic loading. The fractures were treated either with BeadEx plus internal fixator, BeadEx plus bone cement or vertebroplasty for comparison.
The height before fracture could almost be restored by BeadEx plus bone cement but not by BeadEx plus fixator and vertebroplasty. The total height loss after cyclic loading was smallest with BeadEx plus bone cement (in median −4.7
mm with respect to the intact specimens) but −6.2
mm with BeadEx plus fixator and −7.8
mm with vertebroplasty. The three-dimensional stability of the specimens was clearly higher if treated with BeadEx plus fixator than with BeadEx plus bone cement or vertebroplasty.
From a biomechanical point of view, BeadEx plus bone cement can be recommended as an alternative to vertebroplasty in the treatment of osteoporotic vertebral body fractures. BeadEx plus fixator can be recommended if additional stability is needed.</description><identifier>ISSN: 0268-0033</identifier><identifier>EISSN: 1879-1271</identifier><identifier>DOI: 10.1016/j.clinbiomech.2006.02.005</identifier><identifier>PMID: 16567025</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Biomechanical Phenomena - methods ; Biomechanics ; Bone Plates ; Bone Screws ; Cadaver ; Cyclic loading ; Equipment Failure Analysis ; Fracture ; Fractures, Compression - etiology ; Fractures, Compression - physiopathology ; Fractures, Compression - surgery ; Fractures, Spontaneous - etiology ; Fractures, Spontaneous - physiopathology ; Fractures, Spontaneous - surgery ; Humans ; In Vitro Techniques ; Joint Instability - etiology ; Joint Instability - physiopathology ; Joint Instability - prevention & control ; Joint Prosthesis ; Lumbar Vertebrae - physiopathology ; Lumbar Vertebrae - surgery ; Osteoporosis - complications ; Osteoporosis - physiopathology ; Osteoporosis - surgery ; Prosthesis Design ; Range of Motion, Articular ; Recovery of Function ; Spinal Fractures - complications ; Spinal Fractures - physiopathology ; Spinal Fractures - surgery ; Spinal Fusion - instrumentation ; Spinal Fusion - methods ; Spine ; Surgical treatment ; Thoracic Vertebrae - physiopathology ; Thoracic Vertebrae - surgery ; Treatment Outcome</subject><ispartof>Clinical biomechanics (Bristol), 2006-08, Vol.21 (7), p.676-682</ispartof><rights>2006 Elsevier Ltd</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c406t-789286bce13a4b6828af455598b8f9333cfd60d34c6de67e133142305c54b5853</citedby><cites>FETCH-LOGICAL-c406t-789286bce13a4b6828af455598b8f9333cfd60d34c6de67e133142305c54b5853</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,786,790,27957,27958</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16567025$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kettler, A.</creatorcontrib><creatorcontrib>Schmoelz, W.</creatorcontrib><creatorcontrib>Shezifi, Y.</creatorcontrib><creatorcontrib>Ohana, N.</creatorcontrib><creatorcontrib>Ben-Arye, A.</creatorcontrib><creatorcontrib>Claes, L.</creatorcontrib><creatorcontrib>Wilke, H.-J.</creatorcontrib><title>Biomechanical performance of the new BeadEx implant in the treatment of osteoporotic vertebral body compression fractures: Restoration and maintenance of height and stability</title><title>Clinical biomechanics (Bristol)</title><addtitle>Clin Biomech (Bristol, Avon)</addtitle><description>Vertebral compression fractures are counted among the most common complications of osteoporosis. For treatment, a new, alternative implant has been developed (BeadEx, Expandis, Hof HaCarmel, Israel). The aim of the present in vitro study was to evaluate whether this implant is able to restore the initial height and three-dimensional stability after fracture and whether it is able to maintain this height and stability during complex cyclic loading.
The BeadEx implant consists of small titanium rolls, which are pressed into the vertebral body through specially designed, hollow pedicle screws. The height and the three-dimensional flexibility of 18 bisegmental spine specimens (nine T12–L2, nine L3–L5) was measured, first, before and after creating a wedge compression fracture at the middle vertebral body (L1 resp. L4), second, after treatment of the fracture, and, third, during and after complex cyclic loading. The fractures were treated either with BeadEx plus internal fixator, BeadEx plus bone cement or vertebroplasty for comparison.
The height before fracture could almost be restored by BeadEx plus bone cement but not by BeadEx plus fixator and vertebroplasty. The total height loss after cyclic loading was smallest with BeadEx plus bone cement (in median −4.7
mm with respect to the intact specimens) but −6.2
mm with BeadEx plus fixator and −7.8
mm with vertebroplasty. The three-dimensional stability of the specimens was clearly higher if treated with BeadEx plus fixator than with BeadEx plus bone cement or vertebroplasty.
From a biomechanical point of view, BeadEx plus bone cement can be recommended as an alternative to vertebroplasty in the treatment of osteoporotic vertebral body fractures. BeadEx plus fixator can be recommended if additional stability is needed.</description><subject>Biomechanical Phenomena - methods</subject><subject>Biomechanics</subject><subject>Bone Plates</subject><subject>Bone Screws</subject><subject>Cadaver</subject><subject>Cyclic loading</subject><subject>Equipment Failure Analysis</subject><subject>Fracture</subject><subject>Fractures, Compression - etiology</subject><subject>Fractures, Compression - physiopathology</subject><subject>Fractures, Compression - surgery</subject><subject>Fractures, Spontaneous - etiology</subject><subject>Fractures, Spontaneous - physiopathology</subject><subject>Fractures, Spontaneous - surgery</subject><subject>Humans</subject><subject>In Vitro Techniques</subject><subject>Joint Instability - etiology</subject><subject>Joint Instability - physiopathology</subject><subject>Joint Instability - prevention & control</subject><subject>Joint Prosthesis</subject><subject>Lumbar Vertebrae - physiopathology</subject><subject>Lumbar Vertebrae - surgery</subject><subject>Osteoporosis - complications</subject><subject>Osteoporosis - physiopathology</subject><subject>Osteoporosis - surgery</subject><subject>Prosthesis Design</subject><subject>Range of Motion, Articular</subject><subject>Recovery of Function</subject><subject>Spinal Fractures - complications</subject><subject>Spinal Fractures - physiopathology</subject><subject>Spinal Fractures - surgery</subject><subject>Spinal Fusion - instrumentation</subject><subject>Spinal Fusion - methods</subject><subject>Spine</subject><subject>Surgical treatment</subject><subject>Thoracic Vertebrae - physiopathology</subject><subject>Thoracic Vertebrae - surgery</subject><subject>Treatment Outcome</subject><issn>0268-0033</issn><issn>1879-1271</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><recordid>eNqNkcGO0zAQhi0EYrsLr4DMhVvD2I4dhxtbLSzSSkgIzpbjTKirJA62u9CX4hlxt0Vwg5PlmW_-356fkJcMKgZMvd5VbvRz58OEbltxAFUBrwDkI7JiumnXjDfsMVkBV3oNIMQFuUxpBwA1l81TcsGUVA1wuSI_r08qdvbOjnTBOIQ42dkhDQPNW6QzfqfXaPubH9RPy2jnTP380MkRbZ6wFAoaUsawhBiyd_QeY8YuFsEu9AfqwrRETMmHmQ7Rurwvtzf0E6Ycos3Hsp17Olk_Z5x_m2_Rf93mh07KtvOjz4dn5Mlgx4TPz-cV-fLu5vPmdn338f2Hzdu7tatB5XWjW65V55AJW3dKc22HWkrZ6k4PrRDCDb2CXtRO9aiagglWcwHSybqTWoor8uqku8TwbV_eaSafHI7l-xj2ySitQHPO_gmyhtfQNqKA7Ql0MaQUcTBL9JONB8PAHFM1O_NXquaYqgFuSqpl9sXZZN9N2P-ZPMdYgM0JwLKTe4_RJOex7LH3EV02ffD_YfMLxhu9QQ</recordid><startdate>20060801</startdate><enddate>20060801</enddate><creator>Kettler, A.</creator><creator>Schmoelz, W.</creator><creator>Shezifi, Y.</creator><creator>Ohana, N.</creator><creator>Ben-Arye, A.</creator><creator>Claes, L.</creator><creator>Wilke, H.-J.</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>7TS</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20060801</creationdate><title>Biomechanical performance of the new BeadEx implant in the treatment of osteoporotic vertebral body compression fractures: Restoration and maintenance of height and stability</title><author>Kettler, A. ; Schmoelz, W. ; Shezifi, Y. ; Ohana, N. ; Ben-Arye, A. ; Claes, L. ; Wilke, H.-J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c406t-789286bce13a4b6828af455598b8f9333cfd60d34c6de67e133142305c54b5853</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Biomechanical Phenomena - methods</topic><topic>Biomechanics</topic><topic>Bone Plates</topic><topic>Bone Screws</topic><topic>Cadaver</topic><topic>Cyclic loading</topic><topic>Equipment Failure Analysis</topic><topic>Fracture</topic><topic>Fractures, Compression - etiology</topic><topic>Fractures, Compression - physiopathology</topic><topic>Fractures, Compression - surgery</topic><topic>Fractures, Spontaneous - etiology</topic><topic>Fractures, Spontaneous - physiopathology</topic><topic>Fractures, Spontaneous - surgery</topic><topic>Humans</topic><topic>In Vitro Techniques</topic><topic>Joint Instability - etiology</topic><topic>Joint Instability - physiopathology</topic><topic>Joint Instability - prevention & control</topic><topic>Joint Prosthesis</topic><topic>Lumbar Vertebrae - physiopathology</topic><topic>Lumbar Vertebrae - surgery</topic><topic>Osteoporosis - complications</topic><topic>Osteoporosis - physiopathology</topic><topic>Osteoporosis - surgery</topic><topic>Prosthesis Design</topic><topic>Range of Motion, Articular</topic><topic>Recovery of Function</topic><topic>Spinal Fractures - complications</topic><topic>Spinal Fractures - physiopathology</topic><topic>Spinal Fractures - surgery</topic><topic>Spinal Fusion - instrumentation</topic><topic>Spinal Fusion - methods</topic><topic>Spine</topic><topic>Surgical treatment</topic><topic>Thoracic Vertebrae - physiopathology</topic><topic>Thoracic Vertebrae - surgery</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kettler, A.</creatorcontrib><creatorcontrib>Schmoelz, W.</creatorcontrib><creatorcontrib>Shezifi, Y.</creatorcontrib><creatorcontrib>Ohana, N.</creatorcontrib><creatorcontrib>Ben-Arye, A.</creatorcontrib><creatorcontrib>Claes, L.</creatorcontrib><creatorcontrib>Wilke, H.-J.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Physical Education Index</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical biomechanics (Bristol)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kettler, A.</au><au>Schmoelz, W.</au><au>Shezifi, Y.</au><au>Ohana, N.</au><au>Ben-Arye, A.</au><au>Claes, L.</au><au>Wilke, H.-J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Biomechanical performance of the new BeadEx implant in the treatment of osteoporotic vertebral body compression fractures: Restoration and maintenance of height and stability</atitle><jtitle>Clinical biomechanics (Bristol)</jtitle><addtitle>Clin Biomech (Bristol, Avon)</addtitle><date>2006-08-01</date><risdate>2006</risdate><volume>21</volume><issue>7</issue><spage>676</spage><epage>682</epage><pages>676-682</pages><issn>0268-0033</issn><eissn>1879-1271</eissn><notes>ObjectType-Article-2</notes><notes>SourceType-Scholarly Journals-1</notes><notes>ObjectType-Feature-1</notes><notes>content type line 23</notes><notes>ObjectType-Article-1</notes><notes>ObjectType-Feature-2</notes><abstract>Vertebral compression fractures are counted among the most common complications of osteoporosis. For treatment, a new, alternative implant has been developed (BeadEx, Expandis, Hof HaCarmel, Israel). The aim of the present in vitro study was to evaluate whether this implant is able to restore the initial height and three-dimensional stability after fracture and whether it is able to maintain this height and stability during complex cyclic loading.
The BeadEx implant consists of small titanium rolls, which are pressed into the vertebral body through specially designed, hollow pedicle screws. The height and the three-dimensional flexibility of 18 bisegmental spine specimens (nine T12–L2, nine L3–L5) was measured, first, before and after creating a wedge compression fracture at the middle vertebral body (L1 resp. L4), second, after treatment of the fracture, and, third, during and after complex cyclic loading. The fractures were treated either with BeadEx plus internal fixator, BeadEx plus bone cement or vertebroplasty for comparison.
The height before fracture could almost be restored by BeadEx plus bone cement but not by BeadEx plus fixator and vertebroplasty. The total height loss after cyclic loading was smallest with BeadEx plus bone cement (in median −4.7
mm with respect to the intact specimens) but −6.2
mm with BeadEx plus fixator and −7.8
mm with vertebroplasty. The three-dimensional stability of the specimens was clearly higher if treated with BeadEx plus fixator than with BeadEx plus bone cement or vertebroplasty.
From a biomechanical point of view, BeadEx plus bone cement can be recommended as an alternative to vertebroplasty in the treatment of osteoporotic vertebral body fractures. BeadEx plus fixator can be recommended if additional stability is needed.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>16567025</pmid><doi>10.1016/j.clinbiomech.2006.02.005</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
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| ispartof | Clinical biomechanics (Bristol), 2006-08, Vol.21 (7), p.676-682 |
| issn | 0268-0033 1879-1271 |
| language | eng |
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| source | ScienceDirect Journals |
| subjects | Biomechanical Phenomena - methods Biomechanics Bone Plates Bone Screws Cadaver Cyclic loading Equipment Failure Analysis Fracture Fractures, Compression - etiology Fractures, Compression - physiopathology Fractures, Compression - surgery Fractures, Spontaneous - etiology Fractures, Spontaneous - physiopathology Fractures, Spontaneous - surgery Humans In Vitro Techniques Joint Instability - etiology Joint Instability - physiopathology Joint Instability - prevention & control Joint Prosthesis Lumbar Vertebrae - physiopathology Lumbar Vertebrae - surgery Osteoporosis - complications Osteoporosis - physiopathology Osteoporosis - surgery Prosthesis Design Range of Motion, Articular Recovery of Function Spinal Fractures - complications Spinal Fractures - physiopathology Spinal Fractures - surgery Spinal Fusion - instrumentation Spinal Fusion - methods Spine Surgical treatment Thoracic Vertebrae - physiopathology Thoracic Vertebrae - surgery Treatment Outcome |
| title | Biomechanical performance of the new BeadEx implant in the treatment of osteoporotic vertebral body compression fractures: Restoration and maintenance of height and stability |
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