Calcium absorption in postmenopausal Chinese women: a randomized crossover intervention study

The Ca intake and food sources of Chinese postmenopausal women are quite different from those of their Western counterparts. But, little information on Ca metabolism is available in Chinese populations. We determined true fractional calcium absorption (TFCA), true Ca absorption ( = TFCA × Ca intake,...

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Bibliographic Details
Published in:British journal of nutrition 2007, Vol.97 (1), p.160-166
Main Authors: Chen, Yu-ming, Teucher, Birgit, Tang, Xin-yi, Dainty, Jack R., Lee, Kenneth K. C., Woo, Jean L. F., Ho, Suzanne C.
Format: Article
Language:English
Subjects:
Absorption
Acids
adults
Agriculture
Biological and medical sciences
Biomarkers - blood
Calcium
Calcium - metabolism
Calcium - urine
Calcium absorption
Calcium Isotopes - administration & dosage
Calcium Isotopes - analysis
Calcium Isotopes - metabolism
Calcium, Dietary - administration & dosage
Calcium, Dietary - metabolism
China
Chinese
Collagen Type I - blood
Cross-Over Studies
Diet
Dietary calcium
Dietary intake
dietary minerals
dietary nutrient sources
elderly
Excretion
Feeding. Feeding behavior
Female
Food intake
Food sources
Fractures
Fruit juices
Fundamental and applied biological sciences. Psychology
Humans
intestinal absorption
Intestinal Absorption - physiology
Isotopes
Linear Models
menopause
Metabolism
Middle Aged
Milk
nutrient intake
nutrient uptake
nutritional intervention
Parathyroid Hormone - blood
Peptides - blood
Polyethylene
Post-menopause
Postmenopausal women
Postmenopause - metabolism
Regression Analysis
Regression models
Stable isotopes
True fractional absorption
Urine
Vertebrates: anatomy and physiology, studies on body, several organs or systems
women
Womens health
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Summary:The Ca intake and food sources of Chinese postmenopausal women are quite different from those of their Western counterparts. But, little information on Ca metabolism is available in Chinese populations. We determined true fractional calcium absorption (TFCA), true Ca absorption ( = TFCA × Ca intake, Va), urinary Ca excretion (Vu) and the difference between Va and Vu (Va − u), in response to three dietary Ca intake levels. Twenty-one healthy postmenopausal Chinese women aged 49–64 years were recruited for this randomized crossover trial from a general community, Guangzhou, China. Subjects were randomly assigned to receive 0, 500 and 1000 mg Ca/d for 5 weeks separated by 2-week washout periods. TFCA using Ca stable isotopes, total urinary Ca excretion and Ca intake were determined after 4 weeks of adaptation. Mean values for total Ca intake (Vi) of the three phases were 391 (sd 197), 880 (sd 130) and 1382 (sd 160) mg/d. On usual diet, TFCA, Vu, Va and Va − u were 0·57 (sd 0·12), 175 (sd 59) mg/d, 216 (sd 98) mg/d and 41 (sd 99) mg/d, respectively. With the supplementations of 500 and 1000 mg Ca/d, TFCA significantly decreased to 0·52 (sd 0·12) and 0·43 (sd 0·13) (P 
ISSN:0007-1145
1475-2662
DOI:10.1017/S0007114507210141