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Appearance of skin lesions in cattle populations vaccinated against lumpy skin disease: Statutory challenge
Abstract The ultimate goal of a vaccine is to protect vaccinated animals against re-exposure to the same pathogen and provide sterile immunity. However, a cutaneous clinical manifestation appeared, following re-exposure of cattle that had been vaccinated with the RM65 strain, to LSDV infection durin...
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| Published in: | Vaccine 2009-03, Vol.27 (10), p.1500-1503 |
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| creator | Brenner, J Bellaiche, M Gross, E Elad, D Oved, Z Haimovitz, M Wasserman, A Friedgut, O Stram, Y Bumbarov, V Yadin, H |
| description | Abstract The ultimate goal of a vaccine is to protect vaccinated animals against re-exposure to the same pathogen and provide sterile immunity. However, a cutaneous clinical manifestation appeared, following re-exposure of cattle that had been vaccinated with the RM65 strain, to LSDV infection during an epidemic in 2006–2007. Four thousand six hundred and seven vaccinated cows entered the study after being re-exposed to LSDV infection. Of them, 513 (11%) presented lumps, and there was a marked difference between the proportions of dairy and feedlot animals that were affected: 146 out of 3517 and 367 out of 1090 (6.6 and 33.7%, respectively). This data suggests that the potency of the vaccine need to be re-assessed for beef cattle. |
| doi_str_mv | 10.1016/j.vaccine.2009.01.020 |
| format | article |
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However, a cutaneous clinical manifestation appeared, following re-exposure of cattle that had been vaccinated with the RM65 strain, to LSDV infection during an epidemic in 2006–2007. Four thousand six hundred and seven vaccinated cows entered the study after being re-exposed to LSDV infection. Of them, 513 (11%) presented lumps, and there was a marked difference between the proportions of dairy and feedlot animals that were affected: 146 out of 3517 and 367 out of 1090 (6.6 and 33.7%, respectively). This data suggests that the potency of the vaccine need to be re-assessed for beef cattle.</description><identifier>ISSN: 0264-410X</identifier><identifier>EISSN: 1873-2518</identifier><identifier>DOI: 10.1016/j.vaccine.2009.01.020</identifier><identifier>PMID: 19186204</identifier><identifier>CODEN: VACCDE</identifier><language>eng</language><publisher>Kidlington: Elsevier Ltd</publisher><subject>Allergy and Immunology ; Animals ; Applied microbiology ; Beef ; Biological and medical sciences ; Cattle ; Disease ; Drug dosages ; Factory farming ; Female ; Fundamental and applied biological sciences. Psychology ; Genome, Viral ; Genomes ; Infections ; Israel ; Laboratories ; Lumpy skin disease ; Lumpy Skin Disease - immunology ; Lumpy Skin Disease - prevention & control ; Lumpy Skin Disease - virology ; Lumpy skin disease virus - genetics ; Lumpy skin disease virus - immunology ; Lumpy skin disease virus - isolation & purification ; Male ; Microbiology ; Re-exposure ; Sheep ; Skin - immunology ; Skin - virology ; Skin diseases ; Vaccination ; Vaccines ; Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) ; Vaccines, Attenuated - adverse effects ; Veterinary medicine ; Viral Vaccines - adverse effects</subject><ispartof>Vaccine, 2009-03, Vol.27 (10), p.1500-1503</ispartof><rights>Elsevier Ltd</rights><rights>2009 Elsevier Ltd</rights><rights>2009 INIST-CNRS</rights><rights>Copyright Elsevier Limited Mar 4, 2009</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c507t-65a91c51735d122d525ec42cf99a69c2239718e4e05c3df13078a0b2ac32c9f63</citedby><cites>FETCH-LOGICAL-c507t-65a91c51735d122d525ec42cf99a69c2239718e4e05c3df13078a0b2ac32c9f63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,786,790,27957,27958</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=21289252$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19186204$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Brenner, J</creatorcontrib><creatorcontrib>Bellaiche, M</creatorcontrib><creatorcontrib>Gross, E</creatorcontrib><creatorcontrib>Elad, D</creatorcontrib><creatorcontrib>Oved, Z</creatorcontrib><creatorcontrib>Haimovitz, M</creatorcontrib><creatorcontrib>Wasserman, A</creatorcontrib><creatorcontrib>Friedgut, O</creatorcontrib><creatorcontrib>Stram, Y</creatorcontrib><creatorcontrib>Bumbarov, V</creatorcontrib><creatorcontrib>Yadin, H</creatorcontrib><title>Appearance of skin lesions in cattle populations vaccinated against lumpy skin disease: Statutory challenge</title><title>Vaccine</title><addtitle>Vaccine</addtitle><description>Abstract The ultimate goal of a vaccine is to protect vaccinated animals against re-exposure to the same pathogen and provide sterile immunity. However, a cutaneous clinical manifestation appeared, following re-exposure of cattle that had been vaccinated with the RM65 strain, to LSDV infection during an epidemic in 2006–2007. Four thousand six hundred and seven vaccinated cows entered the study after being re-exposed to LSDV infection. Of them, 513 (11%) presented lumps, and there was a marked difference between the proportions of dairy and feedlot animals that were affected: 146 out of 3517 and 367 out of 1090 (6.6 and 33.7%, respectively). This data suggests that the potency of the vaccine need to be re-assessed for beef cattle.</description><subject>Allergy and Immunology</subject><subject>Animals</subject><subject>Applied microbiology</subject><subject>Beef</subject><subject>Biological and medical sciences</subject><subject>Cattle</subject><subject>Disease</subject><subject>Drug dosages</subject><subject>Factory farming</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Genome, Viral</subject><subject>Genomes</subject><subject>Infections</subject><subject>Israel</subject><subject>Laboratories</subject><subject>Lumpy skin disease</subject><subject>Lumpy Skin Disease - immunology</subject><subject>Lumpy Skin Disease - prevention & control</subject><subject>Lumpy Skin Disease - virology</subject><subject>Lumpy skin disease virus - genetics</subject><subject>Lumpy skin disease virus - immunology</subject><subject>Lumpy skin disease virus - isolation & purification</subject><subject>Male</subject><subject>Microbiology</subject><subject>Re-exposure</subject><subject>Sheep</subject><subject>Skin - immunology</subject><subject>Skin - virology</subject><subject>Skin diseases</subject><subject>Vaccination</subject><subject>Vaccines</subject><subject>Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)</subject><subject>Vaccines, Attenuated - adverse effects</subject><subject>Veterinary medicine</subject><subject>Viral Vaccines - adverse effects</subject><issn>0264-410X</issn><issn>1873-2518</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><recordid>eNqFkk9v1DAQxS0EokvhI4AiIbglzNixN-YAqir-SZU4FCRulutMine9SRo7lfbbkzQRlXrpyZb1e29m_Iax1wgFAqoPu-LWOudbKjiALgAL4PCEbbDaipxLrJ6yDXBV5iXCnxP2IsYdAEiB-jk7QY2V4lBu2P6s78kOtnWUdU0W977NAkXftTGbrs6mFCjru34MNt29LmVtojqz19a3MWVhPPTHRVv7SDbSx-wy2TSmbjhm7q8NgdpresmeNTZEerWep-z31y-_zr_nFz-__Tg_u8idhG3KlbQancStkDVyXksuyZXcNVpbpR3nQm-xopJAOlE3KGBbWbji1gnudKPEKXu_-PZDdzNSTObgo6MQbEvdGI1SWkHJ4VFwQrTSyCfw7QNw141DOw1hUGFVCQF3dnKh3NDFOFBj-sEf7HA0CGYOzezMGpqZQzOAZtG9Wd3HqwPV96o1pQl4twI2OhuaOS4f_3MceaW5nNv8vHA0_e6tp8FE52mKtvYDuWTqzj_ayqcHDi741k9F93SkeD-1idyAuZw3bF4w0PNyVVr8A-sHzIk</recordid><startdate>20090304</startdate><enddate>20090304</enddate><creator>Brenner, J</creator><creator>Bellaiche, M</creator><creator>Gross, E</creator><creator>Elad, D</creator><creator>Oved, Z</creator><creator>Haimovitz, M</creator><creator>Wasserman, A</creator><creator>Friedgut, O</creator><creator>Stram, Y</creator><creator>Bumbarov, V</creator><creator>Yadin, H</creator><general>Elsevier Ltd</general><general>Elsevier</general><general>Elsevier Limited</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7RV</scope><scope>7T2</scope><scope>7T5</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88C</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0R</scope><scope>M0S</scope><scope>M0T</scope><scope>M1P</scope><scope>M2O</scope><scope>M7N</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20090304</creationdate><title>Appearance of skin lesions in cattle populations vaccinated against lumpy skin disease: Statutory challenge</title><author>Brenner, J ; Bellaiche, M ; Gross, E ; Elad, D ; Oved, Z ; Haimovitz, M ; Wasserman, A ; Friedgut, O ; Stram, Y ; Bumbarov, V ; Yadin, H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c507t-65a91c51735d122d525ec42cf99a69c2239718e4e05c3df13078a0b2ac32c9f63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Allergy and Immunology</topic><topic>Animals</topic><topic>Applied microbiology</topic><topic>Beef</topic><topic>Biological and medical sciences</topic><topic>Cattle</topic><topic>Disease</topic><topic>Drug dosages</topic><topic>Factory farming</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. 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However, a cutaneous clinical manifestation appeared, following re-exposure of cattle that had been vaccinated with the RM65 strain, to LSDV infection during an epidemic in 2006–2007. Four thousand six hundred and seven vaccinated cows entered the study after being re-exposed to LSDV infection. Of them, 513 (11%) presented lumps, and there was a marked difference between the proportions of dairy and feedlot animals that were affected: 146 out of 3517 and 367 out of 1090 (6.6 and 33.7%, respectively). This data suggests that the potency of the vaccine need to be re-assessed for beef cattle.</abstract><cop>Kidlington</cop><pub>Elsevier Ltd</pub><pmid>19186204</pmid><doi>10.1016/j.vaccine.2009.01.020</doi><tpages>4</tpages></addata></record> |
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| source | ScienceDirect Journals |
| subjects | Allergy and Immunology Animals Applied microbiology Beef Biological and medical sciences Cattle Disease Drug dosages Factory farming Female Fundamental and applied biological sciences. Psychology Genome, Viral Genomes Infections Israel Laboratories Lumpy skin disease Lumpy Skin Disease - immunology Lumpy Skin Disease - prevention & control Lumpy Skin Disease - virology Lumpy skin disease virus - genetics Lumpy skin disease virus - immunology Lumpy skin disease virus - isolation & purification Male Microbiology Re-exposure Sheep Skin - immunology Skin - virology Skin diseases Vaccination Vaccines Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Vaccines, Attenuated - adverse effects Veterinary medicine Viral Vaccines - adverse effects |
| title | Appearance of skin lesions in cattle populations vaccinated against lumpy skin disease: Statutory challenge |
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