DNA profiling in India: Addressing issues of sample preservation, databasing, marker selection, & statistical approaches

DNA technology is the gold standard with respect to the identification of individuals from biological evidence. The technology offers the convenience of a universally similar approach and methodology for analysis across the globe. However, the technology has not realised its full potential in India...

Full description

Saved in:
Bibliographic Details
Published in:Science & justice 2024-07, Vol.64 (4), p.389-396
Main Authors: Sahajpal, Vivek, Bhandari, Deepika
Format: Article
Language:English
Subjects:
Databases, Nucleic Acid
DNA - analysis
DNA database
DNA Fingerprinting - methods
DNA profiling
Forensic evidence
Forensic Genetics - methods
Genetic Markers
Humans
India
Sexual assault
Specimen Handling - methods
Statistical interpretation
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by
cites cdi_FETCH-LOGICAL-c241t-ae3430f5fe1b8a0064ba7b92321e5defdd129fb2dc674d8e7c216e6988cf5b0b3
container_end_page 396
container_issue 4
container_start_page 389
container_title Science & justice
container_volume 64
creator Sahajpal, Vivek
Bhandari, Deepika
description DNA technology is the gold standard with respect to the identification of individuals from biological evidence. The technology offers the convenience of a universally similar approach and methodology for analysis across the globe. However, the technology has not realised its full potential in India due to the lack of a DNA database and lacunae in sample collection and preservation from the scene of crime and victims (especially those of sexual assault). Further, statistical interpretation of DNA results is non-existent in the majority of cases. Though the latest technologies and developments in the field of DNA analysis are being adopted and implemented,very little has been enacted practically to improve optimise sample collection and preservation. This article discusses current casework scenarios that highlight the pitfalls and ambiguous areas in the field of DNA analysis, especially with respect DNA databases, sampling, andstatistical approaches to genetic data analysis. Possible solutions and mitigation measures are suggested.
doi_str_mv 10.1016/j.scijus.2024.05.003
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_3082628241</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1355030624000509</els_id><sourcerecordid>3082628241</sourcerecordid><originalsourceid>FETCH-LOGICAL-c241t-ae3430f5fe1b8a0064ba7b92321e5defdd129fb2dc674d8e7c216e6988cf5b0b3</originalsourceid><addsrcrecordid>eNp9kE1v1DAQhi0EoqXwDxDyCXFowvgzWQ5Iq_JVqYILnC3HHoOXbLJ4shX8e7ykcORky35mXr0PY08FtAKEfblrKeTdkVoJUrdgWgB1j52LvrON1kber3dlTAMK7Bl7RLQDMJ2w8JCdqQ1IY6w-Zz_ffNzyQ5lTHvP0leeJX08x-1d8G2NBoj-PREckPidOfn8YsfJIWG79kufpkke_-MGfyEu-9-U7Fk44Ylh_n3NaKkhLDn7k_lCzfPiG9Jg9SH4kfHJ3XrAv795-vvrQ3Hx6f321vWmC1GJpPCqtIJmEYug9gNWD74aNVFKgiZhiFHKTBhmD7XTssQtSWLSbvg_JDDCoC_Zi3VuDf9Qai9tnCjiOfsL5SE5BL63sa1hF9YqGMhMVTO5Qcm30ywlwJ-du51bn7uTcgXHVeR17dpdwHPYY_w39lVyB1yuAtedtxnLaglPAmEvV5OKc_5_wG-O6lnI</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3082628241</pqid></control><display><type>article</type><title>DNA profiling in India: Addressing issues of sample preservation, databasing, marker selection, &amp; statistical approaches</title><source>Elsevier</source><creator>Sahajpal, Vivek ; Bhandari, Deepika</creator><creatorcontrib>Sahajpal, Vivek ; Bhandari, Deepika</creatorcontrib><description>DNA technology is the gold standard with respect to the identification of individuals from biological evidence. The technology offers the convenience of a universally similar approach and methodology for analysis across the globe. However, the technology has not realised its full potential in India due to the lack of a DNA database and lacunae in sample collection and preservation from the scene of crime and victims (especially those of sexual assault). Further, statistical interpretation of DNA results is non-existent in the majority of cases. Though the latest technologies and developments in the field of DNA analysis are being adopted and implemented,very little has been enacted practically to improve optimise sample collection and preservation. This article discusses current casework scenarios that highlight the pitfalls and ambiguous areas in the field of DNA analysis, especially with respect DNA databases, sampling, andstatistical approaches to genetic data analysis. Possible solutions and mitigation measures are suggested.</description><identifier>ISSN: 1355-0306</identifier><identifier>ISSN: 1876-4452</identifier><identifier>EISSN: 1876-4452</identifier><identifier>DOI: 10.1016/j.scijus.2024.05.003</identifier><identifier>PMID: 39025564</identifier><language>eng</language><publisher>England: Elsevier B.V</publisher><subject>Databases, Nucleic Acid ; DNA - analysis ; DNA database ; DNA Fingerprinting - methods ; DNA profiling ; Forensic evidence ; Forensic Genetics - methods ; Genetic Markers ; Humans ; India ; Sexual assault ; Specimen Handling - methods ; Statistical interpretation</subject><ispartof>Science &amp; justice, 2024-07, Vol.64 (4), p.389-396</ispartof><rights>2024 The Chartered Society of Forensic Sciences</rights><rights>Copyright © 2024 The Chartered Society of Forensic Sciences. Published by Elsevier B.V. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c241t-ae3430f5fe1b8a0064ba7b92321e5defdd129fb2dc674d8e7c216e6988cf5b0b3</cites><orcidid>0000-0002-1276-3262</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,783,787,27937,27938</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39025564$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sahajpal, Vivek</creatorcontrib><creatorcontrib>Bhandari, Deepika</creatorcontrib><title>DNA profiling in India: Addressing issues of sample preservation, databasing, marker selection, &amp; statistical approaches</title><title>Science &amp; justice</title><addtitle>Sci Justice</addtitle><description>DNA technology is the gold standard with respect to the identification of individuals from biological evidence. The technology offers the convenience of a universally similar approach and methodology for analysis across the globe. However, the technology has not realised its full potential in India due to the lack of a DNA database and lacunae in sample collection and preservation from the scene of crime and victims (especially those of sexual assault). Further, statistical interpretation of DNA results is non-existent in the majority of cases. Though the latest technologies and developments in the field of DNA analysis are being adopted and implemented,very little has been enacted practically to improve optimise sample collection and preservation. This article discusses current casework scenarios that highlight the pitfalls and ambiguous areas in the field of DNA analysis, especially with respect DNA databases, sampling, andstatistical approaches to genetic data analysis. Possible solutions and mitigation measures are suggested.</description><subject>Databases, Nucleic Acid</subject><subject>DNA - analysis</subject><subject>DNA database</subject><subject>DNA Fingerprinting - methods</subject><subject>DNA profiling</subject><subject>Forensic evidence</subject><subject>Forensic Genetics - methods</subject><subject>Genetic Markers</subject><subject>Humans</subject><subject>India</subject><subject>Sexual assault</subject><subject>Specimen Handling - methods</subject><subject>Statistical interpretation</subject><issn>1355-0306</issn><issn>1876-4452</issn><issn>1876-4452</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNp9kE1v1DAQhi0EoqXwDxDyCXFowvgzWQ5Iq_JVqYILnC3HHoOXbLJ4shX8e7ykcORky35mXr0PY08FtAKEfblrKeTdkVoJUrdgWgB1j52LvrON1kber3dlTAMK7Bl7RLQDMJ2w8JCdqQ1IY6w-Zz_ffNzyQ5lTHvP0leeJX08x-1d8G2NBoj-PREckPidOfn8YsfJIWG79kufpkke_-MGfyEu-9-U7Fk44Ylh_n3NaKkhLDn7k_lCzfPiG9Jg9SH4kfHJ3XrAv795-vvrQ3Hx6f321vWmC1GJpPCqtIJmEYug9gNWD74aNVFKgiZhiFHKTBhmD7XTssQtSWLSbvg_JDDCoC_Zi3VuDf9Qai9tnCjiOfsL5SE5BL63sa1hF9YqGMhMVTO5Qcm30ywlwJ-du51bn7uTcgXHVeR17dpdwHPYY_w39lVyB1yuAtedtxnLaglPAmEvV5OKc_5_wG-O6lnI</recordid><startdate>202407</startdate><enddate>202407</enddate><creator>Sahajpal, Vivek</creator><creator>Bhandari, Deepika</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-1276-3262</orcidid></search><sort><creationdate>202407</creationdate><title>DNA profiling in India: Addressing issues of sample preservation, databasing, marker selection, &amp; statistical approaches</title><author>Sahajpal, Vivek ; Bhandari, Deepika</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c241t-ae3430f5fe1b8a0064ba7b92321e5defdd129fb2dc674d8e7c216e6988cf5b0b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Databases, Nucleic Acid</topic><topic>DNA - analysis</topic><topic>DNA database</topic><topic>DNA Fingerprinting - methods</topic><topic>DNA profiling</topic><topic>Forensic evidence</topic><topic>Forensic Genetics - methods</topic><topic>Genetic Markers</topic><topic>Humans</topic><topic>India</topic><topic>Sexual assault</topic><topic>Specimen Handling - methods</topic><topic>Statistical interpretation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sahajpal, Vivek</creatorcontrib><creatorcontrib>Bhandari, Deepika</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Science &amp; justice</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sahajpal, Vivek</au><au>Bhandari, Deepika</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>DNA profiling in India: Addressing issues of sample preservation, databasing, marker selection, &amp; statistical approaches</atitle><jtitle>Science &amp; justice</jtitle><addtitle>Sci Justice</addtitle><date>2024-07</date><risdate>2024</risdate><volume>64</volume><issue>4</issue><spage>389</spage><epage>396</epage><pages>389-396</pages><issn>1355-0306</issn><issn>1876-4452</issn><eissn>1876-4452</eissn><abstract>DNA technology is the gold standard with respect to the identification of individuals from biological evidence. The technology offers the convenience of a universally similar approach and methodology for analysis across the globe. However, the technology has not realised its full potential in India due to the lack of a DNA database and lacunae in sample collection and preservation from the scene of crime and victims (especially those of sexual assault). Further, statistical interpretation of DNA results is non-existent in the majority of cases. Though the latest technologies and developments in the field of DNA analysis are being adopted and implemented,very little has been enacted practically to improve optimise sample collection and preservation. This article discusses current casework scenarios that highlight the pitfalls and ambiguous areas in the field of DNA analysis, especially with respect DNA databases, sampling, andstatistical approaches to genetic data analysis. Possible solutions and mitigation measures are suggested.</abstract><cop>England</cop><pub>Elsevier B.V</pub><pmid>39025564</pmid><doi>10.1016/j.scijus.2024.05.003</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0002-1276-3262</orcidid></addata></record>
fulltext fulltext
identifier ISSN: 1355-0306
ispartof Science & justice, 2024-07, Vol.64 (4), p.389-396
issn 1355-0306
1876-4452
1876-4452
language eng
recordid cdi_proquest_miscellaneous_3082628241
source Elsevier
subjects Databases, Nucleic Acid
DNA - analysis
DNA database
DNA Fingerprinting - methods
DNA profiling
Forensic evidence
Forensic Genetics - methods
Genetic Markers
Humans
India
Sexual assault
Specimen Handling - methods
Statistical interpretation
title DNA profiling in India: Addressing issues of sample preservation, databasing, marker selection, & statistical approaches
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-11-11T09%3A45%3A20IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=DNA%20profiling%20in%20India:%20Addressing%20issues%20of%20sample%20preservation,%20databasing,%20marker%20selection,%20&%20statistical%20approaches&rft.jtitle=Science%20&%20justice&rft.au=Sahajpal,%20Vivek&rft.date=2024-07&rft.volume=64&rft.issue=4&rft.spage=389&rft.epage=396&rft.pages=389-396&rft.issn=1355-0306&rft.eissn=1876-4452&rft_id=info:doi/10.1016/j.scijus.2024.05.003&rft_dat=%3Cproquest_cross%3E3082628241%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c241t-ae3430f5fe1b8a0064ba7b92321e5defdd129fb2dc674d8e7c216e6988cf5b0b3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=3082628241&rft_id=info:pmid/39025564&rfr_iscdi=true