Loading…
Infection thresholds for two interacting pathogens in a wild animal population
We present a model for the dynamics of two interacting pathogen variants in a wild animal host population. Using the next-generation matrix approach we define the invasion threshold for one pathogen variant when the other is already established and at steady state. We then provide explicit criteria...
Saved in:
Published in: | Mathematical biosciences 2024-09, Vol.375, p.109258, Article 109258 |
---|---|
Main Author: | |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites |
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
cited_by | |
---|---|
cites | cdi_FETCH-LOGICAL-c212t-19a04bb1b544f2027704e4e116d382afcfa8668ecbb3811aac09398d59bc3a2a3 |
container_end_page | |
container_issue | |
container_start_page | 109258 |
container_title | Mathematical biosciences |
container_volume | 375 |
creator | Roberts, M.G. |
description | We present a model for the dynamics of two interacting pathogen variants in a wild animal host population. Using the next-generation matrix approach we define the invasion threshold for one pathogen variant when the other is already established and at steady state. We then provide explicit criteria for the special cases where: i) the two pathogen variants exclude each other; ii) one variant excludes the other; iii) the population dynamics of hosts infected with both variants are independent of the order of infection; iv) there is no interaction between the variants; and v) one variant enhances transmission of the other.
•A model for the interaction of two pathogen variants in an ecosystem.•A threshold quantity for the invasion by one pathogen variant when the other is present.•Explicit derivation of the threshold quantity for a selection of special cases.•An alternative quantity taking different values but with the same threshold. |
doi_str_mv | 10.1016/j.mbs.2024.109258 |
format | article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_3080633655</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0025556424001184</els_id><sourcerecordid>3080633655</sourcerecordid><originalsourceid>FETCH-LOGICAL-c212t-19a04bb1b544f2027704e4e116d382afcfa8668ecbb3811aac09398d59bc3a2a3</originalsourceid><addsrcrecordid>eNp9kMtOwzAQRS0EEqXwAey8ZJPiZ-KIFap4VKpgA2vLcSatq9QOdkrF3-MqrFmNZube0Z2D0C0lC0poeb9b7Ju0YISJ3NdMqjM0o6qqC065OEczQpgspCzFJbpKaUcIrSgtZ-ht5Tuwowsej9sIaRv6NuEuRDweA3Z-hGjy2m_wYMZt2IBPeYoNPrq-xca7venxEIZDb05HrtFFZ_oEN391jj6fnz6Wr8X6_WW1fFwXllE2FrQ2RDQNbaQQXQ5dVUSAgJyo5YqZznZGlaUC2zRcUWqMJTWvVSvrxnLDDJ-ju-nuEMPXAdKo9y5Z6HvjIRyS5kSRkvNSyiylk9TGkFKETg8xp44_mhJ9Yqd3OrPTJ3Z6Ypc9D5MH8g_fDqJO1oG30LqYaek2uH_cv1JLd44</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3080633655</pqid></control><display><type>article</type><title>Infection thresholds for two interacting pathogens in a wild animal population</title><source>ScienceDirect Freedom Collection 2022-2024</source><source>Backfile Package - Mathematics (Legacy) [YMT]</source><creator>Roberts, M.G.</creator><creatorcontrib>Roberts, M.G.</creatorcontrib><description>We present a model for the dynamics of two interacting pathogen variants in a wild animal host population. Using the next-generation matrix approach we define the invasion threshold for one pathogen variant when the other is already established and at steady state. We then provide explicit criteria for the special cases where: i) the two pathogen variants exclude each other; ii) one variant excludes the other; iii) the population dynamics of hosts infected with both variants are independent of the order of infection; iv) there is no interaction between the variants; and v) one variant enhances transmission of the other.
•A model for the interaction of two pathogen variants in an ecosystem.•A threshold quantity for the invasion by one pathogen variant when the other is present.•Explicit derivation of the threshold quantity for a selection of special cases.•An alternative quantity taking different values but with the same threshold.</description><identifier>ISSN: 0025-5564</identifier><identifier>ISSN: 1879-3134</identifier><identifier>EISSN: 1879-3134</identifier><identifier>DOI: 10.1016/j.mbs.2024.109258</identifier><language>eng</language><publisher>Elsevier Inc</publisher><subject>Basic reproduction number ; Ecology ; Epidemiology ; Interacting pathogen variants ; Invasion thresholds ; Next-generation matrix</subject><ispartof>Mathematical biosciences, 2024-09, Vol.375, p.109258, Article 109258</ispartof><rights>2024 The Author(s)</rights><rights>Copyright © 2024 The Author(s). Published by Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c212t-19a04bb1b544f2027704e4e116d382afcfa8668ecbb3811aac09398d59bc3a2a3</cites><orcidid>0000-0003-2693-5093</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0025556424001184$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>315,786,790,3583,27957,27958,46038</link.rule.ids></links><search><creatorcontrib>Roberts, M.G.</creatorcontrib><title>Infection thresholds for two interacting pathogens in a wild animal population</title><title>Mathematical biosciences</title><description>We present a model for the dynamics of two interacting pathogen variants in a wild animal host population. Using the next-generation matrix approach we define the invasion threshold for one pathogen variant when the other is already established and at steady state. We then provide explicit criteria for the special cases where: i) the two pathogen variants exclude each other; ii) one variant excludes the other; iii) the population dynamics of hosts infected with both variants are independent of the order of infection; iv) there is no interaction between the variants; and v) one variant enhances transmission of the other.
•A model for the interaction of two pathogen variants in an ecosystem.•A threshold quantity for the invasion by one pathogen variant when the other is present.•Explicit derivation of the threshold quantity for a selection of special cases.•An alternative quantity taking different values but with the same threshold.</description><subject>Basic reproduction number</subject><subject>Ecology</subject><subject>Epidemiology</subject><subject>Interacting pathogen variants</subject><subject>Invasion thresholds</subject><subject>Next-generation matrix</subject><issn>0025-5564</issn><issn>1879-3134</issn><issn>1879-3134</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNp9kMtOwzAQRS0EEqXwAey8ZJPiZ-KIFap4VKpgA2vLcSatq9QOdkrF3-MqrFmNZube0Z2D0C0lC0poeb9b7Ju0YISJ3NdMqjM0o6qqC065OEczQpgspCzFJbpKaUcIrSgtZ-ht5Tuwowsej9sIaRv6NuEuRDweA3Z-hGjy2m_wYMZt2IBPeYoNPrq-xca7venxEIZDb05HrtFFZ_oEN391jj6fnz6Wr8X6_WW1fFwXllE2FrQ2RDQNbaQQXQ5dVUSAgJyo5YqZznZGlaUC2zRcUWqMJTWvVSvrxnLDDJ-ju-nuEMPXAdKo9y5Z6HvjIRyS5kSRkvNSyiylk9TGkFKETg8xp44_mhJ9Yqd3OrPTJ3Z6Ypc9D5MH8g_fDqJO1oG30LqYaek2uH_cv1JLd44</recordid><startdate>202409</startdate><enddate>202409</enddate><creator>Roberts, M.G.</creator><general>Elsevier Inc</general><scope>6I.</scope><scope>AAFTH</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-2693-5093</orcidid></search><sort><creationdate>202409</creationdate><title>Infection thresholds for two interacting pathogens in a wild animal population</title><author>Roberts, M.G.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c212t-19a04bb1b544f2027704e4e116d382afcfa8668ecbb3811aac09398d59bc3a2a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Basic reproduction number</topic><topic>Ecology</topic><topic>Epidemiology</topic><topic>Interacting pathogen variants</topic><topic>Invasion thresholds</topic><topic>Next-generation matrix</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Roberts, M.G.</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Mathematical biosciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Roberts, M.G.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Infection thresholds for two interacting pathogens in a wild animal population</atitle><jtitle>Mathematical biosciences</jtitle><date>2024-09</date><risdate>2024</risdate><volume>375</volume><spage>109258</spage><pages>109258-</pages><artnum>109258</artnum><issn>0025-5564</issn><issn>1879-3134</issn><eissn>1879-3134</eissn><notes>ObjectType-Article-1</notes><notes>SourceType-Scholarly Journals-1</notes><notes>ObjectType-Feature-2</notes><notes>content type line 23</notes><abstract>We present a model for the dynamics of two interacting pathogen variants in a wild animal host population. Using the next-generation matrix approach we define the invasion threshold for one pathogen variant when the other is already established and at steady state. We then provide explicit criteria for the special cases where: i) the two pathogen variants exclude each other; ii) one variant excludes the other; iii) the population dynamics of hosts infected with both variants are independent of the order of infection; iv) there is no interaction between the variants; and v) one variant enhances transmission of the other.
•A model for the interaction of two pathogen variants in an ecosystem.•A threshold quantity for the invasion by one pathogen variant when the other is present.•Explicit derivation of the threshold quantity for a selection of special cases.•An alternative quantity taking different values but with the same threshold.</abstract><pub>Elsevier Inc</pub><doi>10.1016/j.mbs.2024.109258</doi><orcidid>https://orcid.org/0000-0003-2693-5093</orcidid><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0025-5564 |
ispartof | Mathematical biosciences, 2024-09, Vol.375, p.109258, Article 109258 |
issn | 0025-5564 1879-3134 1879-3134 |
language | eng |
recordid | cdi_proquest_miscellaneous_3080633655 |
source | ScienceDirect Freedom Collection 2022-2024; Backfile Package - Mathematics (Legacy) [YMT] |
subjects | Basic reproduction number Ecology Epidemiology Interacting pathogen variants Invasion thresholds Next-generation matrix |
title | Infection thresholds for two interacting pathogens in a wild animal population |
url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-09-23T01%3A31%3A20IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Infection%20thresholds%20for%20two%20interacting%20pathogens%20in%20a%20wild%20animal%20population&rft.jtitle=Mathematical%20biosciences&rft.au=Roberts,%20M.G.&rft.date=2024-09&rft.volume=375&rft.spage=109258&rft.pages=109258-&rft.artnum=109258&rft.issn=0025-5564&rft.eissn=1879-3134&rft_id=info:doi/10.1016/j.mbs.2024.109258&rft_dat=%3Cproquest_cross%3E3080633655%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c212t-19a04bb1b544f2027704e4e116d382afcfa8668ecbb3811aac09398d59bc3a2a3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=3080633655&rft_id=info:pmid/&rfr_iscdi=true |